80 research outputs found
Missing value imputation in multi-environment trials: Reconsidering the Krzanowski method
Development of a novel diagnostic system for a telepsychiatric application: a pilot validation study
Metabolic changes in concussed American football players during the acute and chronic post-injury phases
<p>Abstract</p> <p>Background</p> <p>Despite negative neuroimaging findings many athletes display neurophysiological alterations and post-concussion symptoms that may be attributable to neurometabolic alterations.</p> <p>Methods</p> <p>The present study investigated the effects of sports concussion on brain metabolism using <sup>1</sup>H-MR Spectroscopy by comparing a group of 10 non-concussed athletes with a group of 10 concussed athletes of the same age (mean: 22.5 years) and education (mean: 16 years) within both the acute and chronic post-injury phases. All athletes were scanned 1-6 days post-concussion and again 6-months later in a 3T Siemens MRI.</p> <p>Results</p> <p>Concussed athletes demonstrated neurometabolic impairment in prefrontal and motor (M1) cortices in the acute phase where NAA:Cr levels remained depressed relative to controls. There was some recovery observed in the chronic phase where Glu:Cr levels returned to those of control athletes; however, there was a pathological increase of m-I:Cr levels in M1 that was only present in the chronic phase.</p> <p>Conclusions</p> <p>These results confirm cortical neurometabolic changes in the acute post-concussion phase as well as recovery and continued metabolic abnormalities in the chronic phase. The results indicate that complex pathophysiological processes differ depending on the post-injury phase and the neurometabolite in question.</p
A 5-Minute Cognitive Assessment for Safe Remote Use in Patients With COVID-19: Clinical Case Series
Paradoxical complete and spontaneous resolution of depression, psychosis, and suicidal ideation following a traumatic brain injury
Rating of pre-injury symptoms over time in patients with mild traumatic brain injury: the good-old-days bias revisited
The utility of the Sports Concussion Assessment Tool in hospitalized traumatic brain injury patients
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