135 research outputs found

    Transgender Bathroom Rights

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    After winning the right to same-sex marriage in all 50 states in June, 2015, the LGBT community is once again battling in court for its rights, this time for the right of transgender people to use bathrooms and locker rooms that match their gender identity. In its “Dear Colleague Letter on Transgender Students,” the Federal Government has recently interpreted federal law as requiring that transgender students be permitted to use bathroom and locker rooms that correspond with their gender identity in schools receiving federal funding. In two separate lawsuits, 20 states have challenged the legitimacy of this interpretation. This Article examines the current court battles over transgender bathroom and locker room rights and discusses possible outcomes of the most contentious legal issues in dispute. These issues include: the procedures used by the Federal Government in issuing its interpretation; the substantial legitimacy of the interpretation; and the Constitutional authority of the Federal Government to issue its interpretation. The Article concludes that courts should uphold the Federal Government’s recent interpretation of federal civil rights law because the Federal Government’s interpretation is a reasonable interpretation, lawfully issued, that mirrors the best medical and psychiatric practices for the protection and inclusion of a vulnerable group

    Understanding the Culture Care Practices of Rural Immigrant Mexican Women

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    The purpose of this ethnonursing study was to understand the culture care meanings, expressions, patterns and practices of immigrant Mexican women who live in a rural community in Ohio. Leininger\u27s Culture Care Diversity and Universality Theory was utilized as an organizing framework in studying the domain of inquiry. Interviews were conducted with twenty-four general informants and twelve key informants all of whom were immigrant Mexican women. Exhaustive analysis of audio-taped interviews revealed nine data categories and five patterns from which three main themes emerged. Respecting and supporting cultural identity, self-determination, self-reliance and the role of mothers were discovered as significant culture care values of informants. These findings also detailed what immigrant Mexican women value and expect from nurses in the professional caring relationship. A pictorial model was developed to illustrate the interrelationships of these findings and culturally congruent care. Implications and recommendations for nursing theory, practice, education, administration, and research are offered with directions for future nursing research

    Dossier on Govan Young: Exploring children’s historical consciousness through film and archaeology

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    Govan Young (2017) is a 30-minute documentary in which schoolchildren from Glasgow learn of the area’s important but largely unknown medieval history. This dossier brings together four essays that reflect on the film from various academic perspectives – film studies, archaeology and education – to explore how schoolchildren might learn about the past, and develop a historical consciousness, by participating in film-making projects. The dossier also reflects on how educators can learn from those whom they are supposedly teaching, thereby highlighting that experimental pedagogical projects often bring unexpected learning outcomes into being. Consequently, educators must resist the pressures to predict the outcomes of projects, and must strive to keep the future open-ended

    Feminist Perspectives on Bostock v. Clay County, Georgia

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    This jointly-authored essay is a conversation about the Supreme Court’s recent and groundbreaking decision (Bostock v. Clayton County) that held that discrimination based on sexual orientation or gender identity is discrimination based on sex, and therefore prohibited by Title VII of the Civil Rights Act of 1964. While many scholars are writing about this case, we are doing something unique. We are analyzing this decision from feminist perspectives. We are the editors and four of the authors of a book recently published by Cambridge University Press: Feminist Judgments: Rewritten Employment Discrimination Opinions. This book contains fifteen Supreme Court and Courts of Appeals employment discrimination cases that have been rewritten using feminist perspectives, along with commentaries for each of the rewritten opinions. Two of those rewritten opinions are Courts of Appeals cases involving gender identity (Etsitty v. Utah Transit Authority) and sexual orientation (Hively v. Ivy Tech Community College). Because the book was already in production when Bostock was decided, we were unable to incorporate this momentous case into our book. And yet, given our experiences rewriting and editing opinions from feminist perspectives, we have something to say about Bostock and its significance for LGBTQ+ employment cases and employment discrimination law more broadly. Accordingly, we wrote this essay, which has three goals: first, to introduce our book; second, to analyze the Bostock case and its effect on employment discrimination law as it relates to sexual orientation and gender identity; and third, to discuss more broadly the effect of Bostock on employment discrimination jurisprudence through a feminist lens. Throughout the essay, we are attempting to answer the question of whether Bostock is a feminist opinion. Our answers are varied and even uncertain; but ultimately, we conclude that even though we, as feminists, might have written it differently, the LGBTQ+ community deserves to celebrate this momentous victory

    Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae)

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    <p>Abstract</p> <p>Background</p> <p>Cryptophytes are an enigmatic group of unicellular eukaryotes with plastids derived by secondary (i.e., eukaryote-eukaryote) endosymbiosis. Cryptophytes are unusual in that they possess four genomes–a host cell-derived nuclear and mitochondrial genome and an endosymbiont-derived plastid and 'nucleomorph' genome. The evolutionary origins of the host and endosymbiont components of cryptophyte algae are at present poorly understood. Thus far, a single complete mitochondrial genome sequence has been determined for the cryptophyte <it>Rhodomonas salina</it>. Here, the second complete mitochondrial genome of the cryptophyte alga <it>Hemiselmis andersenii </it>CCMP644 is presented.</p> <p>Results</p> <p>The <it>H. andersenii </it>mtDNA is 60,553 bp in size and encodes 30 structural RNAs and 36 protein-coding genes, all located on the same strand. A prominent feature of the genome is the presence of a ~20 Kbp long intergenic region comprised of numerous tandem and dispersed repeat units of between 22–336 bp. Adjacent to these repeats are 27 copies of palindromic sequences predicted to form stable DNA stem-loop structures. One such stem-loop is located near a GC-rich and GC-poor region and may have a regulatory function in replication or transcription. The <it>H. andersenii </it>mtDNA shares a number of features in common with the genome of the cryptophyte <it>Rhodomonas salina</it>, including general architecture, gene content, and the presence of a large repeat region. However, the <it>H. andersenii </it>mtDNA is devoid of inverted repeats and introns, which are present in <it>R. salina</it>. Comparative analyses of the suite of tRNAs encoded in the two genomes reveal that the <it>H. andersenii </it>mtDNA has lost or converted its original <it>trnK(uuu) </it>gene and possesses a <it>trnS</it>-derived '<it>trnK(uuu)</it>', which appears unable to produce a functional tRNA. Mitochondrial protein coding gene phylogenies strongly support a variety of previously established eukaryotic groups, but fail to resolve the relationships among higher-order eukaryotic lineages.</p> <p>Conclusion</p> <p>Comparison of the <it>H. andersenii </it>and <it>R. salina </it>mitochondrial genomes reveals a number of cryptophyte-specific genomic features, most notably the presence of a large repeat-rich intergenic region. However, unlike <it>R. salina</it>, the <it>H. andersenii </it>mtDNA does not possess introns and lacks a Lys-tRNA, which is presumably imported from the cytosol.</p

    Pulmonary non-tuberculous mycobacteria in colonisation and disease in The Gambia

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    The clinical relevance of pulmonary non-tuberculous mycobacteria (PNTM) in The Gambia is unknown. The aim of this study was to estimate the prevalence of non-tuberculous mycobacteria (NTM) in colonisation, and the burden of clinically relevant pulmonary NTM (PNTM) disease in The Gambia. This was a cross-sectional study of the prevalence of NTM in participants aged ≥ 15 years, in a nationwide tuberculosis (TB) prevalence survey between December 2011 and January 2013. We enrolled 903 participants with suspected NTM and NTM cultures were confirmed by 16S rRNA gene sequencing analyses. We applied the American Thoracic Society/Infectious Disease Society of America (ATS/IDSA) diagnostic criteria to determine clinical relevance of NTM. A total of 575 participants had acid-fast bacilli (AFB) positive Mycobacterial Growth Indicator Tube (MGIT) cultures and 229 (39.8%) were NTM. M. avium complex was by far the most isolated NTM (71.0%), followed by M. fortuitum (9.5%) and M. nonchromogenicum (2.9%). Older participants (> 24 years old) were four times more likely to have NTM in their sputa. Only 20.5% (9/44) NTM cases met the ATS/IDSA criteria for NTM disease. This study provides important data on the prevalence of NTM in pulmonary samples of suspected TB cases with AFB positive cultures from a nationally representative population in The Gambia. Enhanced PNTM surveillance is recommended to better understand the contribution of NTM to pulmonary disease

    Pulmonary non-tuberculous mycobacteria in colonisation and disease in The Gambia

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    The clinical relevance of pulmonary non-tuberculous mycobacteria (PNTM) in The Gambia is unknown. The aim of this study was to estimate the prevalence of non-tuberculous mycobacteria (NTM) in colonisation, and the burden of clinically relevant pulmonary NTM (PNTM) disease in The Gambia. This was a cross-sectional study of the prevalence of NTM in participants aged ≥ 15 years, in a nationwide tuberculosis (TB) prevalence survey between December 2011 and January 2013. We enrolled 903 participants with suspected NTM and NTM cultures were confirmed by 16S rRNA gene sequencing analyses. We applied the American Thoracic Society/Infectious Disease Society of America (ATS/IDSA) diagnostic criteria to determine clinical relevance of NTM. A total of 575 participants had acid-fast bacilli (AFB) positive Mycobacterial Growth Indicator Tube (MGIT) cultures and 229 (39.8%) were NTM. M. avium complex was by far the most isolated NTM (71.0%), followed by M. fortuitum (9.5%) and M. nonchromogenicum (2.9%). Older participants (> 24 years old) were four times more likely to have NTM in their sputa. Only 20.5% (9/44) NTM cases met the ATS/IDSA criteria for NTM disease. This study provides important data on the prevalence of NTM in pulmonary samples of suspected TB cases with AFB positive cultures from a nationally representative population in The Gambia. Enhanced PNTM surveillance is recommended to better understand the contribution of NTM to pulmonary disease

    Pediatric Bacterial Meningitis Surveillance in Niger: Increased Importance of Neisseria meningitidis Serogroup C, and a Decrease in Streptococcus pneumoniae Following 13-Valent Pneumococcal Conjugate Vaccine Introduction.

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    BACKGROUND: Meningitis is endemic in Niger. Haemophilus influenzae type b (Hib) vaccine and the 13-valent pneumococcal conjugate vaccine (PCV13) were introduced in 2008 and 2014, respectively. Vaccination campaign against Neisseria meningitidis serogroup A was carried out in 2010-2011. We evaluated changes in pathogen distribution using data from hospital-based surveillance in Niger from 2010 through 2016. METHODS: Cerebrospinal fluid (CSF) specimens from children <5 years old with suspected meningitis were tested to detect vaccine-preventable bacterial pathogens. Confirmatory identification and serotyping/grouping of Streptococcus pneumoniae, N. meningitidis, and H. influenzae were done. Antimicrobial susceptibility testing and whole genome sequencing were performed on S. pneumoniae isolates. RESULTS: The surveillance included 2580 patients with suspected meningitis, of whom 80.8% (2085/2580) had CSF collected. Bacterial meningitis was confirmed in 273 patients: 48% (131/273) was N. meningitidis, 45% (123/273) S. pneumoniae, and 7% (19/273) H. influenzae. Streptococcus pneumoniae meningitis decreased from 34 in 2014, to 16 in 2016. PCV13 serotypes made up 88% (7/8) of S. pneumoniae meningitis prevaccination and 20% (5/20) postvaccination. Neisseria meningitidis serogroup C (NmC) was responsible for 59% (10/17) of serogrouped N. meningitidis meningitis. Hib caused 67% (2/3) of the H. influenzae meningitis isolates serotyped. Penicillin resistance was found in 16% (4/25) of S. pneumoniae isolates. Sequence type 217 was the most common lineage among S. pneumoniae isolates. CONCLUSIONS: Neisseria meningitidis and S. pneumoniae remain important causes of meningitis in children in Niger. The decline in the numbers of S. pneumoniae meningitis post-PCV13 is encouraging and should continue to be monitored. NmC is the predominant serogroup causing N. meningitidis meningitis
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