43 research outputs found

    Combustion behavior profiling of single pulverized coal particles in a drop tube furnace through high-speed imaging and image analysis

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    Experimental investigations into the combustion behaviors of single pulverized coal particles are carried out based on high-speed imaging and image processing techniques. A high-speed video camera is employed to acquire the images of coal particles during their residence time in a visual drop tube furnace. Computer algorithms are developed to determine the characteristic parameters of the particles from the images extracted from the videos obtained. The parameters are used to quantify the combustion behaviorsof the burning particle in terms of its size, shape, surface roughness, rotation frequency and luminosity. Two sets of samples of the same coal with different particle sizes are studied using the techniques developed. Experimental results show that the coal with different particle sizes exhibits distinctly different combustion behaviors. In particular, for the large coal particle (150–212 lm), the combustion of volatiles and char takes place sequentially with clear fragmentation at the early stage of the char combustion.For the small coal particle (106–150 lm), however, the combustion of volatiles and char occurs simultaneouslywith no clear fragmentation. The size of the two burning particles shows a decreasing trend withperiodic variation attributed to the rapid rotations of the particles. The small particle rotates at a frequencyof around 30 Hz, in comparison to 20 Hz for the large particle due to a greater combustion rate.The luminous intensity of the large particle shows two peaks, which is attributed to the sequential combustionof volatiles and char. The luminous intensity of the small particle illustrates a monotonously decreasing trend, suggesting again a simultaneous devolatilization/volatile and char combustion

    A framework for analyzing institutional gaps in natural resource governance

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    In this paper we present the Inter-Institutional Gap(IIG) Framework as a novel approach to conceptualizing the often-overlooked interconnectivity of different rule-levels between formal and informal institutions in a resource system. This framework goes beyond the existing concepts of legal pluralism, institutional void, structural hole, and cultural mismatch, each of which offer valuable insights to particular gaps between formal and informal institutions, but do not sufficiently address the interaction at every rule level (i.e. constitutional choice, collective choice and operational choice rules). In order to demonstrate the potential of our framework for better understanding the underlying causes of inter-institutional gaps, we apply it to four case studies that encompass diverse geographical locations, governance scales, and social-ecological systems. Results reveal inter-institutional gaps can be created when there are unintended, unforeseen or hidden gaps between different rule hierarchies in two or more simultaneously operating institutions. More specifically we observe that: i) inter-institutional gaps are co-existing, therefore if a certain gap is identified, other gaps may be expected; ii) certain gaps may reveal latent gaps; and iii) intermediaries may be key to addressing inter-institutional gaps. In many cases, sustainable natural resource management and regulation cannot be achieved without directly addressing the inter-institutional gaps that exist between formal and informal institutions operating in the same resource system. The Framework facilitates analysis and understanding of multi-level governance structures in pursuit of addressing complex natural resource management issues

    Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als

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    Amyotrophic Lateral Sclerosis (ALS), is a fatal neurodegenerative disorder, with TDP-43 inclusions as a major pathological hallmark. Using a Drosophila model of TDP-43 proteinopathy we found significant alterations in glucose metabolism including increased pyruvate, suggesting that modulating glycolysis may be neuroprotective. Indeed, a high sugar diet improves locomotor and lifespan defects caused by TDP-43 proteinopathy in motor neurons or glia, but not muscle, suggesting that metabolic dysregulation occurs in the nervous system. Overexpressing human glucose transporter GLUT-3 in motor neurons mitigates TDP-43 dependent defects in synaptic vesicle recycling and improves locomotion. Furthermore, PFK mRNA, a key indicator of glycolysis, is upregulated in flies and patient derived iPSC motor neurons with TDP-43 pathology. Surprisingly, PFK overexpression rescues TDP-43 induced locomotor deficits. These findings from multiple ALS models show that mechanistically, glycolysis is upregulated in degenerating motor neurons as a compensatory mechanism and suggest that increased glucose availability is protective

    Characterising pulverised fuel ignition in a visual drop tube furnace by use of a high-speed imaging technique

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    This study investigates the ignition characteristics of pulverised coal, biomass and co-firing by use of a visual drop tube furnace (VDTF) and a high speed imaging technique. Three coals (anthracite, a bituminous coal and a lignite), four biomasses (Pine, Eucalyptus, Olive Residue and Miscanthus) and various biomass-coal mixtures were tested. With each coal, biomass or their mixture, a distinct flame was established within the VDTF through the continuous feeding of the fuel under the environment of air and at a furnace temperature of 800 °C. To observe the ignition point, a Phantom v12.1 high-speed camera was used to capture the videos of fuel combustion at 500 frames per second (FPS). A technique was developed using MATLAB's image analysis tool to automate the ignition point detection. The results of the image processing were used to statistically analyse and determine the changes to the ignition behaviour with different fuels and co-firing ratios. The results obtained with the tested coals have shown that the distance to ignition increases as the coal volatile matter content decreases, whereas the opposite trend was found for the biomass fuels. Further, the addition of biomass to the anthracite significantly reduces the distance to ignition but a much less pronounced effect on the ignition was found when biomass was co-fired with the bituminous coal or lignite. The synergistic effect on the ignition of biomass-anthracite mixture is mainly attributed to the high volatile content and the potential effects of catalysis from the alkali metals present in the biomass. The results of this study have shown that the VDTF testing coupled with the image analysis technique allows for an effective and simple method of characterising ignition behaviours of pulverised coal, biomass and their mixtures

    Aspects of sustainability in the destination branding process: a bottom-up approach

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    The concept of sustainability is based on the premise that the inhabitants of a destination should be involved in the way that destination is managed and promoted. At the same time, the literature of place branding emphasizes the important role of local stakeholders in the creation of a true and reliable place brand. In fact, the process of developing a destination brand begins with the aim of shaping the identity of a destination; what the destination stands for. The sustainable dimensions of the destination branding process are explored, while focus groups and structured questionnaires are used to evaluate the usefulness of projection techniques in the process of building a brand identity. It seems that the use of the personification technique could work as an effective destination positioning exercise and as an alternative proposal to the outdated clichés used in tourism promotion

    Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

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    Amyotrophic Lateral Sclerosis (ALS), is a fatal neurodegenerative disorder, with TDP-43 inclusions as a major pathological hallmark. Using a Drosophila model of TDP-43 proteinopathy we found significant alterations in glucose metabolism including increased pyruvate, suggesting that modulating glycolysis may be neuroprotective. Indeed, a high sugar diet improves locomotor and lifespan defects caused by TDP-43 proteinopathy in motor neurons or glia, but not muscle, suggesting that metabolic dysregulation occurs in the nervous system. Overexpressing human glucose transporter GLUT-3 in motor neurons mitigates TDP-43 dependent defects in synaptic vesicle recycling and improves locomotion. Furthermore, PFK mRNA, a key indicator of glycolysis, is upregulated in flies and patient derived iPSC motor neurons with TDP-43 pathology. Surprisingly, PFK overexpression rescues TDP-43 induced locomotor deficits. These findings from multiple ALS models show that mechanistically, glycolysis is upregulated in degenerating motor neurons as a compensatory mechanism and suggest that increased glucose availability is protective.National Institutes of Health [T32GM008659, NS091299]; Howard Hughes Medical Institute; University of Arizona; Arnold and Mabel Beckman Foundation; Association pour la Recherche sur la Sclerose Laterale Amyotrophique et autres Maladies du Motoneurone; Target ALS; Barrow Neurological Foundation; Muscular Dystrophy Association [418515]Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

    Quantity does not always mean quality: the importance of qualitative social science in conservation research

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    Qualitative methods are important in gaining a deep understanding of complex problems and poorly researched areas. They can be particularly useful to help explain underlying conservation problems, as in Rust et al. (2016). However, the significance in choosing and justifying appropriate methodological frameworks in conservation studies should be given more attention to ensure data are collected and analysed appropriately. We thank Potgieter et al. (2017) for their critical analysis of Rust et al. (2016), but they appear unaware of when, why and how such methods should be used. We clarify the methods described in Rust et al. (2016) and explain sampling strategies in qualitative studies. To improve familiarity with qualitative methods among natural scientists we recommend expanded training in social sciences and collaborating with social scientists. Given the scale of human impacts on the environment, this type of nuanced analytical skill is critical for moving conservation forward

    Box C/D RNA-Guided 2′-O Methylations and the Intron of tRNATrp Are Not Essential for the Viability of Haloferax volcanii▿

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    Deleting the box C/D RNA-containing intron in the Haloferax volcanii tRNATrp gene abolishes RNA-guided 2′-O methylations of C34 and U39 residues of tRNATrp. However, this deletion does not affect growth under standard conditions

    PET reconstruction artifact can be minimized by using sinogram correction and filtered back-projection technique

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    Filtered Back-Projection (FBP) has become an outdated image reconstruction technique in new-generation positron emission tomography (PET)/computed tomography (CT) scanners. Iterative reconstruction used in all new-generation PET scanners is a much improved reconstruction technique. Though a well-calibrated PET system can only be used for clinical imaging in few situations like ours, when compromised PET scanner with one PET module bypassed was used for PET acquisition, FBP with sinogram correction proved to be a better reconstruction technique to minimize streak artifact present in the image reconstructed by the iterative technique
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