17 research outputs found
Repeated, protein-encoding heterochromatic genes cause inactivation of a juxtaposed euchromatic gene
AbstractEuchromatic genes are often silenced by rearrangements that place them within or near heterochromatin, a phenomenon known as position effect variegation (PEV). However, little is known about molecular structure of cis-acting heterochromatic fragments responsible for PEV. Here we report that heterochromatic cluster containing Stellate repeats, that encode putative regulatory subunit of protein kinase CK2 cause PEV of a reporter white `mini-gene'. It is the first example of an euchromatic gene being silenced because of the proximity to the natural, well-defined heterochromatic repeat cluster
Expression of two microRNAs, ame-mir-276 and -1000, in the adult honeybee (Apis mellifera) brain
Association of P-mobile element activity and DNA methylation pattern changes in conditions of Drosophila Melanogaster prolonged irradiation
Seepage through earth dam with clay core and toe drain: the Casagrande–Numerov analytical legacy revisited
Computational prediction of microRNA genes in silkworm genome
MicroRNAs (miRNAs) constitute a novel, extensive class of small RNAs (~21 nucleotides), and play important gene-regulation roles during growth and development in various organisms. Here we conducted a homology search to identify homologs of previously validated miRNAs from silkworm genome. We identified 24 potential miRNA genes, and gave each of them a name according to the common criteria. Interestingly, we found that a great number of newly identified miRNAs were conserved in silkworm and Drosophila, and family alignment revealed that miRNA families might possess single nucleotide polymorphisms. miRNA gene clusters and possible functions of complement miRNA pairs are discussed