Microbiome: a new era in normal and pathological changes skin studies

The paper contains review of studies on microbiota and cutaneous microbiome using modern techniques of methagenomic analysis. The existing data on microflora of normal skin and among the patients with acne, seborrhoeic dermatitis, rosacea atopic dermatitis are consequently analyzed. The interaction between microbiome and innate/adaptive immunity is presented The perspectives of knowledge on microbiome both in dermatology and cosmetology are pointed out

Dermocosmetics: beneficial adjuncts in the treatment of acne vulgaris

Introduction: Dermocosmetics are increasingly being recognized as an integral part of acne management. Dermocosmetics may minimize the side effects of acne medications, provide synergistic effects by improving the efficacy of other treatments, and limit exposure to environmental factors such as ultraviolet radiation. We aimed to provide an overview of the active ingredients and different types of preparations used in dermocosmetics for acne, and highlight supporting evidence for their use in clinical practice. Methods: A literature search for selected key words was performed using PubMed. Additional papers were identified based on author expertize. Results and discussion: The different types of active ingredients in dermocosmetics for acne can be classified as: sebum-controlling, antimicrobial, anti-inflammatory, anti-oxidant and/or keratolytic. Such agents may modulate the pathogenic pathways in acne. Dermocosmetics can be formulated as emulsions/creams, cleansers or camouflaging make-up. Dermocosmetics are useful treatment adjuncts for acne and have been shown to improve the clinical signs of acne, reduce transepidermal water loss and modify sebum production. Dermocosmetics have also been associated with reducing side effects of pharmacological treatments, high levels of patient satisfaction and increased adherence to treatment regimens. Together this evidence supports the use of dermocosmetics in clinical practice

Взаимосвязь клинических и психологических характеристик женщин, обращающихся за косметологической помощью

Background. Patients seeking cosmetic help, most commonly, haven`t only defects in appearance, in particular, facial skin, but also experience certain psychological problems in this regard. On the other hand, the reaction to the performed cosmetic correction of the mentioned defects depends, including on the patients psychological characteristics. The study of the correlation between clinical and psychological characteristics should contribute to the individualization of the cosmetological correction process and optimization of the patient life quality. Aims. To establish the correlation between age, clinical and psychological characteristics of women with cosmetic problems of the facial skin. Materials and methods. Using the methods of psychological diagnostics, we examined 110 women who received cosmetic assistance. Semi-quantitative method was used to assess the cosmetic problem intensity, the duration of its existence and the effect of the correction performed. Clinical and psychological research was carried out using the author's structured interview, which questions were aimed at fixing both the formal social positions of the patients and the characteristics of the system of significant relationships. Psychometric research was carried out using standardized questionnaires in order to identify a wide range of personality characteristics. In the course of statistical processing of the results, a frequency analysis of the gradations of nominative and rank signs was carried out using Pearson's 2, as well as a correlation analysis of clinical and psychological characteristics using the Spearman -test. Results. The author traced the statistical correlation between the degree of manifestation of the cosmetic problem and its influence on the psychological state of patients, as well as between the degree of their satisfaction with its solution and a number of personal characteristics and attitudes. Conclusions. The assumption was confirmed that the effect of treatment is determined not only by clinical factors and the possibilities of modern cosmetology, but also by psychological factors, among which the motivational orientation and activity of the individual, which form the basis of patient compliance, are of decisive importance.Обоснование. Пациенты, обращающиеся за косметологической помощью, как правило, не только имеют дефекты внешности, в частности, кожи лица, но и испытывают в связи с этим определенные психологические проблемы. С другой стороны, реакция на проведенную косметологическую коррекцию упомянутых дефектов зависит в том числе и от психологических характеристик пациенток. Изучение взаимосвязи клинических и психологических характеристик должно способствовать индивидуализации процесса косметологической коррекции и оптимизации качества жизни пациенток. Цель исследования. Установить взаимосвязь между возрастом, клиническими и психологическими характеристиками женщин с косметологическими проблемами кожи лица. Методы. С помощью методов психологической диагностики обследовано 110 женщин, получивших косметологическую помощь. Полуколичественным методом оценивали степень выраженности косметологической проблемы, длительность ее существования и эффект от проведенной коррекции. Клинико-психологическое исследование проводили с помощью авторского структурированного интервью, вопросы которого были направлены на фиксацию как формальных социальных позиций пациенток, так и характеристик системы значимых отношений. Психометрическое исследование проводили с использованием стандартизованных опросников с целью выявления широкого спектра характеристик личности. При статистической обработке результатов проведены частотный анализ градаций номинативных и ранговых признаков с помощью 2 Пирсона, а также корреляционный анализ клинических и психологических характеристик с использованием -критерия Спирмена. Результаты. Прослежена статистическая взаимосвязь между степенью выраженности косметологической проблемы и ее влиянием на психологическое состояние пациенток, а также между степенью их удовлетворенности ее решением и рядом личностных характеристик и жизненных установок. Заключение. Подтверждено предположение о том, что эффект лечения определяется не только клиническими факторами и возможностями современной косметологии, но и психологическими факторами, среди которых решающее значение имеют мотивационная направленность и активность личности, составляющие основу комплаентности пациента

Guidelines for treatment of atopic dermatitis (atopic eczema) from American Academy of Dermatology, European Academy of Dermatology and Venereology and Russian Society of Dermatovenereologists and Cosmetologisis. Expert’s opinion

Atopic dermatitis (AD) is a common skin condition treated by dermatologists all over the world. Guidelines for management and treatment of AD have appeared in Europe, USA and Russia recently. the paper contains comparison of European, American and Russian guidelines. Definition of AD, epidemiology, pathophysiology of the disease, clinical features, diagnostic criteria, and risk factors are consistently matched. the analysis demonstrated that guidelines do not contain serious contradictions and principal differences thus stressing their supplementation of each other