482 research outputs found

    PMS58 Burden of Disease in Patients with Diagnosed Rheumatoid Arthritis in Brazil: Results from 2011 National Health and Wellness Survey (NHWS)

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    Use of mulching to curb late blight epidemics on potatoes in ParanĂĄ, Brazil.

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    Potato late blight – PLB is the most destructive foliar fungal disease for the crop in Southern Brazil. Organic farmers are in the urge to find ways to minimize losses due to the disease. Thus, the main objective of this study was to evaluate the effect of mulching on potato crop on late blight epidemic reduction using soil mulching. Two experiments were installed for the spring planting, at Lapa, PR. Treatments were with mulching (60 t/ha fresh weight, plant cover composition was mainly of ryegrass, oats, mixed with wild radish) and no mulching. Cultivars Ágata (susceptible) and BRS Ana (moderately resistant) were used in each experiment. Randomized complete blocks with 4 reps was the experimental design. PLB severity was weekly assessed visually on plots to estimate the area under late blight progress curves (AULBPC) for ANOVA. Plot size was of 6 ten-meter long rows, 0.8 m apart. Harvest was done at the 4 internal rows. There was a significant reduction of the AULBPC for the mulching treatment for both cultivars tested. Mulching also influenced positively commercial yield. There was a significant reduction in weed incidence for the mulching treatment as well. These experiments are under way for the Fall season planting

    Electronic structure and ferroelectricity in SrBi2Ta2O9

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    The electronic structure of SrBi2Ta2O9 is investigated from first-principles, within the local density approximation, using the full-potential linearized augmented plane wave (LAPW) method. The results show that, besides the large Ta(5d)-O(2p) hybridization which is a common feature of the ferroelectric perovskites, there is an important hybridization between bismuth and oxygen states. The underlying static potential for the ferroelectric distortion and the primary source for ferroelectricity is investigated by a lattice-dynamics study using the Frozen Phonon approach.Comment: 17 pages, 7 figures. Phys. Rev. B, in pres

    Preparation and ferroelectric properties of (124)-oriented SrBi4Ti4O15 ferroelectric thin film on (110)-oriented LaNiO3 electrode

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    A (124)-oriented SrBi4Ti4O15 (SBTi) ferroelectric thin film with high volume fraction of {\alpha}SBTi(124)=97% was obtained using a metal organic decomposition process on SiO2/Si substrate coated by (110)-oriented LaNiO3 (LNO) thin film. The remanent polarization and coercive field for (124)-oriented SBTi film are 12.1 {\mu}C/cm2 and 74 kV/cm, respectively. No evident fatigue of (124)-oriented SBTi thin film can be observed after 1{\times}10e9 switching cycles. Besides, the (124)-oriented SBTi film can be uniformly polarized over large areas using a piezoelectric-mode atomic force microscope. Considering that the annealing temperature was 650{\deg}C and the thickness of each deposited layer was merely 30 nm, a long-range epitaxial relationship between SBTi(124) and LNO(110) facets was proposed. The epitaxial relationship was demonstrated based on the crystal structures of SBTi and LNO.Comment: 11 pages, 4 figures, published in Journal of Materials Science: Materials in Electronics (JMSE), 19 (2008), 1031-103

    The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

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    Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the literature, especially studies including the whole spectrum of NAFLD lesions. We aimed to evaluate the association between gut dysbiosis and severe NAFLD lesions, that is, nonalcoholic steatohepatitis (NASH) and fibrosis, in a well-characterized population of adult NAFLD. Fifty-seven patients with biopsy-proven NAFLD were enrolled. Taxonomic composition of gut microbiota was determined using 16S ribosomal RNA gene sequencing of stool samples. Thirty patients had F0/F1 fibrosis stage at liver biopsy (10 with NASH), and 27 patients had significant F≄2 fibrosis (25 with NASH). Bacteroides abundance was significantly increased in NASH and F≄2 patients, whereas Prevotella abundance was decreased. Ruminococcus abundance was significantly higher in F≄2 patients. By multivariate analysis, Bacteroides abundance was independently associated with NASH and Ruminococcus with F≄2 fibrosis. Stratification according to the abundance of these two bacteria generated three patient subgroups with increasing severity of NAFLD lesions. Based on imputed metagenomic profiles, Kyoto Encyclopedia of Genes and Genomes pathways significantly related to NASH and fibrosis F≄2 were mostly related to carbohydrate, lipid, and amino acid metabolism. CONCLUSION: NAFLD severity associates with gut dysbiosis and a shift in metabolic function of the gut microbiota. We identified Bacteroides as independently associated with NASH and Ruminococcus with significant fibrosis. Thus, gut microbiota analysis adds information to classical predictors of NAFLD severity and suggests novel metabolic targets for pre-/probiotics therapies

    Seasonal drought limits tree species across the Neotropics

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    Within the tropics, the species richness of tree communities is strongly and positively associated with precipitation. Previous research has suggested that this macroecological pattern is driven by the negative effect of water-stress on the physiological processes of most tree species. This process implies that the range limits of taxa are defined by their ability to occur under dry conditions, and thus in terms of species distributions it predicts a nested pattern of taxa distribution from wet to dry areas. However, this ‘dry-tolerance’ hypothesis has yet to be adequately tested at large spatial and taxonomic scales. Here, using a dataset of 531 inventory plots of closed canopy forest distributed across the Western Neotropics we investigated how precipitation, evaluated both as mean annual precipitation and as the maximum climatological water deficit, influences the distribution of tropical tree species, genera and families. We find that the distributions of tree taxa are indeed nested along precipitation gradients in the western Neotropics. Taxa tolerant to seasonal drought are disproportionally widespread across the precipitation gradient, with most reaching even the wettest climates sampled; however, most taxa analysed are restricted to wet areas. Our results suggest that the ‘dry tolerance’ hypothesis has broad applicability in the world's most species-rich forests. In addition, the large number of species restricted to wetter conditions strongly indicates that an increased frequency of drought could severely threaten biodiversity in this region. Overall, this study establishes a baseline for exploring how tropical forest tree composition may change in response to current and future environmental changes in this region
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