Análisis del contenido multimedia del vídeo “El Amazonas Arde” de PlayGround, Lima, 2020

En la presente investigación se planteó el siguiente problema ¿Cuáles son las características del contenido multimedia en el vídeo ‘El Amazonas arde’ de PlayGround, 2020? Y se determinó como objetivo, analizar el contenido multimedia en el vídeo ‘El Amazonas arde’ de PlayGround, Lima, 2020. El proceso metodológico se apoyó en el enfoque cualitativo, de tipo aplicada y diseño estudio de caso. Asimismo, se sustenta en la Teoría de la Comunicación Digital Interactiva de Carlos Scolari, haciendo uso de una guía de observación para analizar el contenido que se difundió en el vídeo mencionado. El instrumento utilizado es la ficha de observación y fue validado por tres expertos en la materia, obtenido como resultado un 91% de validez en V Aiken. En los resultados se halló un uso correcto de la integración de elementos multimedia, desde los textos, imagen y sonido, así como subcategorías que profundizan este estudio. Finalmente, se concluyó que el contenido difundido por el medio de comunicación digital PlayGround, es útil para nuevas formas de consumir información en jóvenes

The Role of Demographic History and Selection in Shaping Genetic Diversity of the Galápagos Penguin (Spheniscus mendiculus)

Although many studies have documented the effects of demographic bottlenecks on the genetic diversity of natural populations, there is conflicting evidence of the roles that genetic drift and selection may play in driving changes in genetic variation at adaptive loci. We analyzed genetic variation at microsatellite and mitochondrial loci in conjunction with an adaptive MHC class II locus in the Galápagos penguin (Spheniscus mendiculus), a species that has undergone serial demographic bottlenecks associated with El Niño events through its evolutionary history. We compared levels of variation in the Galápagos penguin to those of its congener, the Magellanic penguin (Spheniscus magellanicus), which has consistently maintained a large population size and thus was used as a non-bottlenecked control. The comparison of neutral and adaptive markers in these two demographically distinct species allowed assessment of the potential role of balancing selection in maintaining levels of MHC variation during bottleneck events. Our analysis suggests that the lack of genetic diversity at both neutral and adaptive loci in the Galápagos penguin likely resulted from its restricted range, relatively low abundance, and history of demographic bottlenecks. The Galápagos penguin revealed two MHC alleles, one mitochondrial haplotype, and six alleles across five microsatellite loci, which represents only a small fraction of the diversity detected in Magellanic penguins. Despite the decreased genetic diversity in the Galápagos penguin, results revealed signals of balancing selection at the MHC, which suggest that selection can mitigate some of the effects of genetic drift during bottleneck events. Although Galápagos penguin populations have persisted for a long time, increased frequency of El Niño events due to global climate change, as well as the low diversity exhibited at immunological loci, may put this species at further risk of extinction

Desafíos del Aprendizaje Profundo en la Visión por Computador

Computer Vision is a field of study within Artificial Intelligence that focuses on developing computational techniques to perceive the world through visual data, such as video or images. Deep Learning has proven to be efficient in visual data analysis and interpretation. Nevertheless, it faces countless challenges given its application in several Computer Vision tasks. This panel brings together Deep Learning experts, who will share information about Deep Learning applications and challenges to overcome in their research fields regarding Computer Vision.La Visión por Computador es un área de estudio en la Inteligencia Artificial que se enfoca en el desarrollo de técnicas computacionales para percibir el mundo a través de entradas visuales, como videos o imágenes. El Aprendizaje Profundo ha demostrado ser una técnica eficiente para el análisis e interpretación de datos visuales. Sin embargo, afronta inúmeros desafíos según su aplicación en las diferentes tareas de la Visión por Computador. Este panel reúne un grupo de expertos en Aprendizaje Profundo, quienes ofrecerán información sobre su aplicación y desafíos a ser superados en sus respectivas áreas de investigación con relación a la Visión por Computador

Desafíos del aprendizaje profundo en la visión por computador

La visión por computador es un área de estudio en la inteligencia artificial que se enfoca en el desarrollo de técnicas computacionales para percibir el mundo a través de entradas visuales, como videos o imágenes. El aprendizaje profundo ha demostrado ser una técnica eficiente para el análisis e interpretación de datos visuales. Sin embargo, afronta innumerables desafíos según su aplicación en las diferentes tareas de la visión por computador. Este panel reúne un grupo de expertos en aprendizaje profundo, quienes ofrecerán información sobre su aplicación y los desafíos en sus respectivas áreas de investigación con relación a la visión por computador

Fibrinogen-to-Albumin Ratio and Blood Urea Nitrogen-to-Albumin Ratio in COVID-19 Patients: A Systematic Review and Meta-Analysis

Fibrinogen-to-albumin ratio (FAR) and blood urea nitrogen-to-albumin ratio (BAR) are inflammatory biomarkers that have been associated with clinical outcomes of multiple diseases. The objective of this study is to evaluate the association of these biomarkers with the severity and mortality of COVID-19 patients. A systematic search was performed in five databases. Observational studies that reported the association between FAR and BAR values with the severity and mortality of COVID-19 patients were included. Random-effects models were used for meta-analyses, and effects were expressed as Odds Ratio (OR) and their 95% confidence intervals (CI). Publication bias was assessed using the Begg test, while the quality assessment was assessed using the Newcastle Ottawa Scale. A total of 21 studies (n = 7949) were included. High FAR values were associated with a higher risk of severity (OR: 2.41; 95% CI 1.41–4.12; p < 0.001) and mortality (OR: 2.05; 95% CI 1.66–2.54; p < 0.001). High BAR values were associated with higher risk of mortality (OR: 4.63; 95% CI 2.11–10.15; p < 0.001). However, no statistically significant association was found between BAR values and the risk of severity (OR: 1.16; 95% CI 0.83–1.63; p = 0.38). High FAR and BAR values were associated with poor clinical outcomes.Revisión por pare

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Proteasas extracelulares producidas por bacterias marinas aisladas de aguas contaminadas con efluentes pesqueros

Un total de 26 cepas de bacterias marinas con actividad proteolítica fueron aisladas de agua de mar contaminadas con efluentes pesqueros; las mismas que se evaluaron en base al crecimiento y formación de halos de actividad en Agar Marino suplementados con caseína al 1%, pH 8,0 e incubados a 25 ºC por 72 h. Cinco cepas, seleccionadas por presentar los mejores halos de actividad fueron evaluadas a su vez por su crecimiento y producción de proteasas a diferentes concentraciones de NaCl, rangos de temperatura y pH; siendo consideradas finalmente como bacterias halotolerantes, psicrotróficas y alcalófilas moderadas. Estas cepas también fueron evaluadas por su actividad proteolítica específica sobre la caseína, siendo la cepa CM48 (Pseudomonas sp.) la que presentó la mejor actividad específica (17,38 U/mg) a las 72 horas, y seguidas por las cepas CM45 (Alcaligenes sp.) (12,09 U/mg) y tres cepas de Aeromonas sp. (CM43, CM44 y CM46) con valores de 12,02; 10,07 y 10,10 U/mg respectivamente

Gestión De La Innovación Tecnológica-II168-201900

El curso de especialidad de la carrera de Ingeniería Industrial dirigido a alumnos del octavo ciclo de carácter teórico ¿ práctico revisa analiza y aplica los conceptos y herramientas básicas para organizar y dirigir los recursos de la organización así como construir redes de colaboración internas y externas con otras entidades con el objetivo de aumentar la capacidad de generación de soluciones innovadoras que permitan obtener nuevos productos procesos y servicios o mejorar significativamente los ya existente

The role of demographic history and selection in shaping genetic diversity of the Galápagos penguin (Spheniscus mendiculus).

Although many studies have documented the effects of demographic bottlenecks on the genetic diversity of natural populations, there is conflicting evidence of the roles that genetic drift and selection may play in driving changes in genetic variation at adaptive loci. We analyzed genetic variation at microsatellite and mitochondrial loci in conjunction with an adaptive MHC class II locus in the Galápagos penguin (Spheniscus mendiculus), a species that has undergone serial demographic bottlenecks associated with El Niño events through its evolutionary history. We compared levels of variation in the Galápagos penguin to those of its congener, the Magellanic penguin (Spheniscus magellanicus), which has consistently maintained a large population size and thus was used as a non-bottlenecked control. The comparison of neutral and adaptive markers in these two demographically distinct species allowed assessment of the potential role of balancing selection in maintaining levels of MHC variation during bottleneck events. Our analysis suggests that the lack of genetic diversity at both neutral and adaptive loci in the Galápagos penguin likely resulted from its restricted range, relatively low abundance, and history of demographic bottlenecks. The Galápagos penguin revealed two MHC alleles, one mitochondrial haplotype, and six alleles across five microsatellite loci, which represents only a small fraction of the diversity detected in Magellanic penguins. Despite the decreased genetic diversity in the Galápagos penguin, results revealed signals of balancing selection at the MHC, which suggest that selection can mitigate some of the effects of genetic drift during bottleneck events. Although Galápagos penguin populations have persisted for a long time, increased frequency of El Niño events due to global climate change, as well as the low diversity exhibited at immunological loci, may put this species at further risk of extinction