Planning benefits realization in a collaborative university-industry R&D funded program

This paper presents a benefits management (BM) approach adopted during the planning of a collaborative university-industry R&D funded program, named IC-HMI Program, in order to pursue benefits realization. The BM approach embraced four main phases: 'Identify expected benefits' 'Plan benefits realization' 'Pursue benefits realization' and 'Transfer and ensure benefits realization' each one comprising key activities that should be performed with a clear set of outputs to be generated. Particular focus is given to the benefits identification, and to the development of a Benefit Breakdown Structure (BBS), assuming the key role of such a formatting technique to target project benefits. It is the first and critical step in the BM process. Based on a review of literature, and the three research methods adopted during the IC-HMI case study analysis: a set of 33 benefits were identified, which can be used by professionals and academics as a checklist for benefits identification of their own initiatives. Additionally, the BBS implemented in IC-HMI program to qualify and better understand each benefit and its intrinsic properties, can be used to facilitate planning and benefits realization.FCT - Fundació Catalana de Trasplantament(SFRH/BPD/111033/2015

An extension of the improving and embedding project management practice framework: Case study analysis

Purpose: The purpose of this paper is to develop and test an extension of a previously conceived framework for improving and embedding project management (PM) practice in organisations. The framework identifies the most useful project management improvement initiatives (PMIIs) and the key factors for embedding PM practice. However, professionals need guidance on how to operationalise such framework in their organisations, therefore a method for applying the framework is developed. Design/methodology/approach: The method being proposed for applying the framework is demonstrated and tested with a large University–Industry consortium case study. During the case study analysis three research methods were applied: participant observation, document analysis and focus groups. Findings: In what concerns both the PMIIs and key embedding factors in the framework, the proposed method comprises their acknowledgement, scoring, relevance analysis, selection and planning. The detailed report on how the framework was applied in the particular case study also sheds light on how University–Industry consortiums can make use of PM to become more successful. Research limitations/implications: The research was performed using only one case study which limits the generalisability of its findings. Practical implications: Detailed guidance is provided for applying the framework’s both constructs, “improving” and “embedding”, through a set of clear steps. Originality/value: The paper shows the explanatory power of the framework for improving and embedding PM practice in a case study, demonstrating that the method for its application is practical and suitable.FCT - Fundació Catalana de Trasplantament(SFRH/BPD/111033/2015

Applying a method for measuring the performance of university-industry R&D collaborations: case study analysis

Collaborations between university and industry are possibly the most important strategic instrument used to increase the efficiency and effectiveness of industrial investments in Research and Development (R&D), and have been increasing, which assigns even more importance to the need for measuring their performance. Therefore, a method to measure university-industry R&D collaborations, named MPUIC, developed based on Design Science Research methodology (DSRM), was applied and validated through a case study. This paper firstly describes some improvements made to the previously developed MPUIC method before its application to a large program between the University of Minho and Bosch Car Multimedia (Portugal). The MPUIC method adopted a weighted scoring approach, and is composed by 31 performance indicators, distributed through the program management life cycle. Secondly, the performance measurement of the case study program is conducted, resulting in a score of 4.4 in a scale of 1 to 5, where 5 indicates "very high" performance. Finally, a questionnaire was administered to evaluate the developed method and, from the 31 performance indicators that compose the method, 29 were evaluated as having a level of relevance above 3 in a scale of 1 to 5 and, from these, 19 were evaluated as having a level of relevance equal to or above 4.This research is sponsored by the Fundação para a Ciência e a Tecnologia FCT (SFRH/BPD/111033/2015), and by the Portugal Incentive System for Research and Technological Development. Project in co-promotion nº 039479/2018 (FoF 2018-2021

Value of project management in university–industry R&D collaborations

Purpose: University–industry projects provide special challenges in understanding and expressing the values required of project management (PM) in delivering stakeholder benefits. This paper presents a framework for understanding, identifying and managing the values of PM in major university–industry R&D projects. Design/methodology/approach: The value framework identifies for each of the key stakeholders, the key PM values that may require to be managed and are largely derived from research literature. Empirical research then explores, prioritises and selects key PM values that need to be managed for a specific project. A large case study is used involving one university and one industry collaborating on a multi-million Euro initiative over six years. Empirical research was conducted by researchers who observed at close quarters, the challenges and successes of managing the competing values of key stakeholders. Findings: The value framework takes a stakeholders' perspective by identifying the respective PM values for each of six stakeholders: university–industry consortium, university, industry, R&D external entities, funding entity and society. Research limitations/implications: The research was performed using only one case study which limits the generalisability of its findings; however, the findings are presented as a decision support aid for project consortia in developing values for their own collaboration. Practical implications: Guidance and decision support are provided to multi-stakeholder research consortia when selecting values that need to be managed for achieving tangible and intangible project benefits. Originality/value: The paper demonstrates a proposed framework for designing and managing the value of PM in large multi-stakeholder university–industry R&D projects.INCT-EN - Instituto Nacional de Ciência e Tecnologia para Excitotoxicidade e Neuroproteção(SFRH/BPD/111033/2015

Cryptorchidism in Children with Zika-Related Microcephaly.

The genitourinary tract was recently identified as a potential site of complications related to the congenital Zika syndrome (CZS). We provide the first report of a series of cryptorchidism cases in 3-year-old children with Zika-related microcephaly who underwent consultations between October 2018 and April 2019 as part of the follow-up of the children cohort of the Microcephaly Epidemic Research Group, Pernambuco, Brazil. Of the 22 males examined, eight (36.4%) presented with cryptorchidism. Among 14 undescended testis cases, 11 (78.6%) could be palpated in the inguinal region. Seven of the eight children had severe microcephaly. Conventional risk factors for cryptorchidism were relatively infrequent in these children. We hypothesize that cryptorchidism is an additional manifestation of CZS present in children with severe microcephaly. As in our cases, for most of the children, the testes were located in the inguinal region, and the possible mechanisms for cryptorchidism were gubernaculum disturbance or cremasteric abnormality

Key initiatives to successfully manage collaborative university-industry R&D: IC-HMI case study

This paper describes the results of a qualitative study to identify the key management initiatives in a successful university-industry (UI) collaborative funded program between the University of Minho (UMinho) and Bosch Car Multimedia Portugal (Bosch), named IC-HMI. The IC-HMI program embraced an overall investment of 54.7 M€ and involved around 500 people throughout the Program's duration (2015-2018). While the literature provides some advice on managing programs and projects, the specific context of UI R&D collaboration is being scarcely reported, demanding a strong research effort to produce effective guidelines. The IC-HMI is considered a successful program for several reasons, as evidenced by the decision of UMinho and Bosch partners to develop a subsequent R&D collaborative program from 2018 to 2021, doubling its investment. The success attained with the IC-HMI program could be somehow explained by key management initiatives adopted, such as the: creation of Program and Project Management Office, definition and communication of a Governance Model, creation of Project Charters, promotion of Alignment Stakeholders Workshops, Project Progress Meetings and creation of Project Transition Plans, among other key initiatives reported in this paper.This research is sponsored by the Fundação para a Ciência e a Tecnologia FCT (SFRH/BPD/111033/2015), and by the Portugal Incentive System for R&D. Project in co-promotion nº 039479/2018 (FoF 2018-2021)

From program strategic planning to program initiation: lessons learned from a collaborative university-industry R&D case study

This paper aims to contribute to knowledge by presenting the lessons learned resultant from a large case study composed by three collaborative University-Industry RD funded programs between the University of Minho (UMinho) and Bosch Car Multimedia Portugal (Bosch). The three programs selected amount to a total investment of above €109 million, over the period between 2013 and 2021, involving more than one thousand University researchers and Industry collaborators. The lessons learned are limited to the time span from Program Strategic Planning, where new project ideas/innovation opportunities are identified and developed for the preparation of the 'Funding Application', to Program Initiation, where the program effectively initiates after the negotiation of the 'Funding Contract'. The collection, analysis and implementation of lessons learned allowed the development of a structured process to guide University-Industry partners on the path to transform some newly identified project ideas into the initiation of a large RD funded program. The proposed process is currently adopted by the governance structure of Bosch and UMinho partnership and other UMinho partnerships with Industry.This work has been supported by FCT – Fundação para a Ciência e Tecnologia within the Project Scope: UID/CEC/00319/2019, by the Research Grant: SFRH/BPD/111033/2015, and by the Portugal Incentive System for Research and Technological Development. Project in co-promotion nº 039334/2018

The frequency and clinical presentation of Zika virus coinfections: a systematic review.

BACKGROUND: There is limited knowledge on the influence of concurrent coinfections on the clinical presentation of Zika virus (ZIKV) disease. METHODS: To better understand the types, frequencies and clinical manifestations of ZIKV coinfections, we did a systematic review of four databases (PubMed, Embase, Web of Science, LILACS) without restrictions for studies on ZIKV coinfections confirmed by nucleic acid (quantitative real-time-PCR) testing of ZIKV and coinfecting pathogens. The review aimed to identify cohort, cross-sectional, case series and case report studies that described frequencies and/or clinical signs and symptoms of ZIKV coinfections. Conference abstracts, reviews, commentaries and studies with imprecise pathogen diagnoses and/or no clinical evaluations were excluded. RESULTS: The search identified 34 articles from 10 countries, comprising 2 cohort, 10 cross-sectional, 8 case series and 14 case report studies. Coinfections were most frequently reported to have occurred with other arthropod-borne viruses (arboviruses); out of the 213 coinfections described, ZIKV infections co-occurred with chikungunya in 115 cases, with dengue in 68 cases and with both viruses in 19 cases. Other coinfecting agents included human immunodeficiency, Epstein-Barr, human herpes and Mayaro viruses, Leptospira spp, Toxoplasma gondii and Schistosoma mansoni. ZIKV-coinfected cases primarily presented with mild clinical features, typical of ZIKV monoinfection; however, 9% of cases in cohort and cross-sectional studies were reported to experience complications. CONCLUSION: Based on the evidence collated in this review, coinfections do not appear to strongly influence the clinical manifestations of uncomplicated ZIKV infections. Further research is needed to confirm whether risk of severe complications is altered when ZIKV infection co-occurs with other infections. PROSPERO REGISTRATION NUMBER: CRD42018111023

A conceptual social media tool for supporting collaborative university-industry R&D programs

This paper aims to help professionals and academics involved in collaborative university-industry RD programs and projects, by presenting a conceptual social media tool that can be used to improve communication and collaboration between internal stakeholders. The social media tool conceptualization was developed based on a case study research strategy. The case selected was a large publicly funded RD collaborative program that covers 30 RD projects carried out by a university and an industry partner. During the case study analysis three research methods were applied: participant observation, document analysis, and focus groups. The social media tool is conceptualized in seven functional building blocks: identity, relationships, sharing, presence conversations, reputation and groups. For each building block, its main objectives and requirements are detailed, within this particular context of collaborative university-industry RD programs and projects.This research is sponsored by the Fundação para a Ciência e a Tecnologia FCT (SFRH/BPD/111033/2015), and by the Portugal Incentive System for Research and Technological Development. Project in co-promotion nº 36265/2013 (Project HMIExcel - 2013-2015)