135 research outputs found
Potassium-modulated physiological performance of mango plants infected by Ceratocystis fimbriata
Pleomorphic Adenoma of External Auditory Canal: Case Report of First Endoscopic Resection and Literature Review
Ceruminous pleomorphic adenoma is a very rare, mostly benign tumor originating from the ceruminal glands in the external auditory canal. Histologically, it is a mixed tumor with epithelial and stromal parts of different proportions, and is recognized today by the World Health Organization (WHO) as a ceruminous adenoma. Similar to the pleomorphic adenoma of salivary glands, recurrence or malignant degeneration with cellular atypia and metastasis can occur on rare occasions. Here, we describe an 87-year old female patient with a growing spherical mass in the right external auditory canal. After exclusive endoscopic tumor resection, a ceruminous pleomorphic adenoma was histologically diagnosed. Due to the absence of nuclear pleomorphism, no increased mitotic rate, no perineural invasion and no fusion transcripts of the MYB or MYBL1 gene loci, an adenoid cystic carcinoma could be excluded. The postoperative course was without any evidence of complications. A literature review identified 44 articles with 49 patients that were considered. Hearing loss and ear sensations were the most commonly reported symptoms. Most cases underwent an excision via an endaural or retroauricular approach. Recurrences were described in four patients, three of which had a malignant transformation.
Keywords: Pleomorphic adenoma; ceruminal gland tumor; ceruminous adenoma; endoscopic ear surgery; external auditory canal
Long-term efficacy assessment of current treatment options for epistaxis in HHT.
PURPOSE
Hereditary hemorrhagic telangiectasia (HHT) is a vascular disorder that presents with recurrent, intractable epistaxis. The aim of this study was to retrospectively analyze the efficacy of various treatment options for epistaxis in patients with HHT, over a period of 18 years, and to correlate these findings with available evidence in the literature.
METHODS
Records of patients with HHT, treated for epistaxis between 2000 and 2018 were analyzed. Treatment procedures carried out and their efficacy were extracted and analyzed.
RESULTS
Forty-three records were evaluated. All patients were given nasal humidifying ointments, 93% required acute treatment with bipolar electrocautery, and 60% underwent atraumatic nasal packing. Recurrent cases were treated medically with tranexamic acid (26%), oestrogen (19%), and bevacizumab (2%). Laser photocoagulation was done in selected cases (40%) and if unsuccessful, septal dermoplasty was performed (2.3%). Endovascular embolization was reserved for life-threatening emergencies (7%).
CONCLUSION
Epistaxis in HHT is not curable, but can be managed by employing a comprehensive stepwise approach. An algorithm for effective and comprehensive management has been presented
Seks in reclame: kan het vrouwen nog wat schelen? Onderzoek naar de attitudes van vrouwen wat betreft de seksuele objectificatie van vrouwelijke modellen in reclame, en het effect daarvan op algemene koopintenties en bedrijfsimago
Bis (2,4,6-Tribromophenyl) Phosphorochloridate: A New Type of Condensing Reagent in Oligonucleotide Synthesis
Oximidobenzotetronic acid ? a sensitive spot test reagent for iron(II), cobalt(II) and copper(II)
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