Local item density modulates adaptation of learned contextual cues

In everyday scenes, searched-for targets do not appear in isolation, but are embedded within configurations of non-target or distractor items. If the position of the target relative to the distractors is invariant, such spatial contingencies are implicitly learned and come to guide visual scanning ("contextual cueing"). However, the effectiveness of contextual cueing depends heavily on the consistency between bottom-up perceptual input and context memory: following configural learning, re-locating targets to an unexpected location within an unchanged distractor context completely abolishes contextual cueing, and gains deriving from the invariant context recover only very slowly with increasing exposure to the changed displays. The current study induces variations of the local target context, i.e., item density, to investigate the relation between this factor and contextual adaptation. The results showed that learned contextual cues can be adapted quickly if the target is re-positioned to a sparse ..

Affective Modulation of Working Memory Maintenance

The present study investigated the impact of task-irrelevant emotional images on the retention of information in spatial working memory (WM). Two experiments employed a delayed matching to-sample task where participants had to maintain the locations of four briefly presented squares. After a short retention interval, a probe item appeared and participants were required to indicate whether the probe position matched one of the previously occupied square positions. During the retention interval, task-irrelevant negative, positive, or neutral emotional pictures were presented. The results revealed a dissociation between negative and positive affect on the participants’ ability to hold spatial locations in WM. While negative affective pictures reduced WM capacity, positive pictures increased WM capacity relative to the neutral images. Moreover, the specific valence and arousal of a given emotional picture was also related to WM performance: While higher valence enhanced WM capacity, higher levels of arousal in turn reduced WM capacity. Together, our findings suggest that emotions up- or down-regulate attention to items in WM and thus modulate the short-term storage of visual information in memory

App-based learning for kindergarten children at home (Learning4Kids): study protocol for cohort 1 and the kindergarten assessments

Children's literacy and mathematical competencies are a critical platform for their successful functioning as individuals in society. However, many children, in particular those with low socio-economic status (SES) backgrounds who may not receive the home support needed to develop to their full potential, are at risk of not reaching sufficient competence levels. The overall aim of this project is to develop innovative computer tablet applications (`apps') and test whether the apps support parents in the provision of high-quality home learning environments (HLEs) and impact positively on the short- and long-term development of children's competencies

Opposite Dynamics of GABA and Glutamate Levels in the Occipital Cortex during Visual Processing

Magnetic resonance spectroscopy (MRS) measures the two most common inhibitory and excitatory neurotransmitters, GABA and glutamate, in the human brain. However, the role of MRS-derived GABA and glutamate signals in relation to system-level neural signaling and behavior is not fully understood. In this study, we investigated levels of GABA and glutamate in the visual cortex of healthy human participants (both genders) in three functional states with increasing visual input. Compared with a baseline state of eyes closed, GABA levels decreased after opening the eyes in darkness and Glx levels remained stable during eyes open but increased with visual stimulation. In relevant states, GABA and Glx correlated with amplitude of fMRI signal fluctuations. Furthermore, visual discriminatory performance correlated with the level of GABA, but not Glx. Our study suggests that differences in brain states can be detected through the contrasting dynamics of GABA and Glx, which has implications in interpreting MRS measurements.Othe