The processing of color preference in the brain

Decades of research has established that humans have preferences for some colors (e.g., blue) and a dislike of others (e.g., dark chartreuse), with preference varying systematically with variation in hue (e.g., Hurlbert & Owen, 2015). Here, we used functional MRI to investigate why humans have likes and dislikes for simple patches of color, and to understand the neural basis of preference, aesthetics and value judgements more generally. We looked for correlations of a behavioural measure of color preference with the blood oxygen level-dependent (BOLD) response when participants performed an irrelevant orientation judgement task on colored squares. A whole brain analysis found a significant correlation between BOLD activity and color preference in the posterior midline cortex (PMC), centred on the precuneus but extending into the adjacent posterior cingulate and cuneus. These results demonstrate that brain activity is modulated by color preference, even when such preferences are irrelevant to the ongoing task the participants are engaged. They also suggest that color preferences automatically influence our processing of the visual world. Interestingly, the effect in the PMC overlaps with regions identified in neuroimaging studies of preference and value judgements of other types of stimuli. Therefore, our findings extends this literature to show that the PMC is related to automatic encoding of subjective value even for basic visual features such as color

Adaptation to variance generalizes across visual domains

Processing the vast amount of visual information available from the world ought to pose a significant challenge to the brain. One of the ways in which the brain appears to encode the structure inherent in the world is through summary statistical representations (e.g., mean size, color etc.). This study investigates whether variance perception can be adapted for color, and then whether the variance adaptation aftereffects generalize from color to another visual domain. In a series of four experiments, we find aftereffects reflecting adaptation to the variance of hues in an ensemble—such that prolonged exposure to a highly variable ensemble of hues makes subsequent ensembles appear less variable in hue. We also found that this effect partially generalized to the perception of orientation variance—adaptation to highly variable color ensembles made subsequent ensembles also appear less variable in orientation. This is a novel demonstration of adaptation aftereffects reflecting processing of visual ensemble information across domains. The results could imply a neural mechanism encoding visual variance that is not selective to the domain from which the variance signal is derived. This mechanism may form the basis for cross-domain visual comparisons, and may play a role in predictive coding, enabling the brain to calibrate to the complexity of the visual environment

Red, yellow, green and blue are not particularly colorful

Colorfulness and saturation have been neglected in research on color appearance and color naming. Perceptual particularities, such as cross-cultural stability, “focality”, “uniqueness”, “salience” and “prominence” have been observed for red, yellow, green, and blue, when those colors were more saturated than other colors in the stimulus samples. The present study tests whether high saturation is a particular property of red, yellow, green and blue, which would explain those observations. First, we carefully determined the category prototypes and unique hues for red, yellow, green, and blue. Using different approaches in two experiments, we assessed discriminable saturation as the number of just-noticeable differences away from the adaptation point (i.e. neutral gray). Results show that some hues can reach much higher levels of maximal saturation than others. However, typical and unique red, yellow, green, and blue are not particularly colorful. Many other, intermediate colors have a larger range of discriminable saturation than these colors. These findings suggest that prior claims of perceptual salience of category prototypes and unique hues actually reflect biases in stimulus sets rather than perceptual properties. Additional analyses show that consistent prototype choices across fundamentally different languages are strongly related to the variation of discriminable saturation in the stimulus sets. Our findings also undermine the idea that every color can be produced by a mixture of unique hues. Finally, the measurements in this study provide a large amount of data on saturation across hues, which allows for reevaluating existing estimates of saturation in future studies

Impact on Hospital Profitability Due to COVID Safety Guidelines

Introduction: The pandemic of COVID 19 presented a unique challenge to hospitals and healthcare systems that they have been struggling to function in. Operating costs had increased with new protocols, planning, operating space, supplies, and staffing. This coupled with the loss of revenue has led to approximately 10% - 20% salary reductions, furloughs, and loss of benefits such as PTO and vacation days to employees. Hospital’s cash reserves are being depleted due to increased operations costs and reduced revenue. Government funding, such as the CARES Act provided by the sanction of the Department of Health and Human Services Office, will only help keep the doors open and not create profitability for the hospitals. Efficiency and cost restructuring have been deemed necessary during the financial crisis brought upon by the COVID 19 pandemic. Purpose: The purpose of this research was to identify the financial components impacting the hospital system’s profitability with new protocols that have been implemented since combating issues related to COVID 19. Methodology: The intended methodology for this qualitative study is a semi-structured interview with managerial employees of healthcare organizations and a literature review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) diagram. Results: The economic impact on hospitals has led to drastic reductions in the profitability of hospitals by eliminating elective surgeries for months, changing the traditional workforce models, and disrupting the supply chain of essential medical equipment and medication. Discussion/Conclusion: The research demonstrated that suspension of elective surgeries, dramatic modifications to the workforce, and disruption to the supply chain have immensely impacted hospitals and their ability to generate profitability

Simulation of the Sampling Distribution of the Mean Can Mislead

Although the use of simulation to teach the sampling distribution of the mean is meant to provide students with sound conceptual understanding, it may lead them astray. We discuss a misunderstanding that can be introduced or reinforced when students who intuitively understand that “bigger samples are better” conduct a simulation to explore the effect of sample size on the properties of the sampling distribution of the mean. From observing the patterns in a typical series of simulated sampling distributions constructed with increasing sample sizes, students reasonably—but incorrectly—conclude that, as the sample size, n, increases, the mean of the (exact) sampling distribution tends to get closer to the population mean and its variance tends to get closer to 2 / , where 2 is the population variance. We show that the patterns students observe are a consequence of the fact that both the variability in the mean and the variability in the variance of simulated sampling distributions constructed from the means of N random samples are inversely related, not only to N, but also to the size of each sample, n. Further, asking students to increase the number of repetitions, N, in the simulation does not change the patterns

Electrophysiological correlates and psychoacoustic characteristics of hearing-motion synaesthesia

People with hearing-motion synaesthesia experience sounds from moving or changing (e.g. flickering) visual stimuli. This phenomenon may be one of the most common forms of synaesthesia but it has rarely been studied and there are no studies of its neural basis. We screened for this in a sample of 200+ individuals, and estimated a prevalence of 4.2%. We also document its characteristics: it tends to be induced by physically moving stimuli (more so than static stimuli which imply motion or trigger illusory motion); and the psychoacoustic features are simple (e.g. “whooshing”) with some systematic correspondences to vision (e.g. faster movement is higher pitch). We demonstrate using event-related potentials that it emerges from early perceptual processing of vision. The synaesthetes have a higher amplitude motion-evoked N2 (165-185 msec), with some evidence of group differences as early as 55-75 msec. We discuss similarities between hearing-motion synaesthesia and previous observations that visual motion triggers auditory activity in the congenitally deaf. It is possible that both conditions reflect the maintenance of multisensory pathways found in early development that most people lose but can be retained in certain people in response to sensory deprivation (in the deaf) or, in people with normal hearing, as a result of other differences (e.g. genes predisposing to synaesthesia)

Specific treatment and outcome of urethrorectal fistula associated with type 1 atresia ani in a juvenile male dog

A four-month-old, entire male, German wirehaired pointer presented with tenesmus due to type I atresia ani and with urination observed through this stenosed anal opening. A positive contrast retrograde urethrogram demonstrated a urethrorectal fistula and stricture of the penile urethra. Urine culture revealed heavy mixed bacterial growth, which was treated with appropriate antibiotics. Surgical correction of the congenital urethrorectal fistula was performed via a perineal approach with a 3.5 French catheter placed retrograde into the fistula to facilitate its dissection. The anal stenosis was addressed by surgical anoplasty and the urethral stricture via a scrotal urethrostomy. The dog recovered well with the owner reporting complete resolution of the clinical signs and urination via the urethrostomy site at six months postoperatively. To the authors’ knowledge, this is the first reported case of congenital urethrorectal fistula associated with type 1 atresia ani in a male dog