Ecological selection of winter wheat as a measure of adaptation to climate change

The study presents the results of a five-year investigation (2018-2023) into the performance of winter wheat varieties Kuryanochka 19 and Rat’ compared to the standard variety Lgovskaya 4. The research aimed to assess the environmental plasticity and adaptability of these new varieties under varying weather conditions. The best growing conditions were observed in the 2021-2022 season, with an environmental index of 1.2 and maximum yields of 8.28 t/ha for Kuryanochka 19 and 8.46 t/ha for Rat’. The study found that both varieties exhibited high resistance to environmental stress factors, with Kuryanochka 19 and Rat’ showing minimum and maximum yields of -2.42 and -2.3, respectively. Additionally, they demonstrated genetic flexibility, with Kuryanochka 19 and Rat’ exhibiting flexibility values of 7.07 and 7.31, respectively, compared to the standard Lgovskaya 4 with a value of 6.44. The varieties also displayed low coefficients of variation (11.9-13.4%) and high homeostaticity (51.5-51.6%). The Kuryanochka 19 variety was highly responsive to improved cultivation conditions, with a regression coefficient for the environment (b) of 2.17, whereas the Rat’ variety was less responsive, with a b value of 0.65

Contacts with Diasporas and Diaspora Organisations as a Key to a Successful Migrant Integration Policy in the EU

We analyse European Commission and European Parliament documents - directives, communications, conclusions, recommendations - and best practices for EU member states' international projects focusing on migrant integration in both the EU states and the countries of origin. Special emphasis is placed on the role of diasporas and the efforts taken by the EU to involve them in the integration process. We stress the need for a new supranational EU immigration and integration policy, in view of new migration trends and the so-called migrant crisis. The study shows that the EU integration policy is directed towards both migrants and host countries and the countries of origin. Since the early 2010s, the involvement of various diaspora organisations in the implementation of the EU migrant integration policy has significantly increased. An analysis of completed projects shows that diasporas have a potential of becoming a key actor in the EU integration policy. We suggest expanding the list of the objectives of the national integration policy of the EU countries. This may be achieved by boosting efforts to reduce the gap in the socio-economic development of the host countries and the countries of origin, particularly, by promoting multilateral cooperation with diaspora organisations

Possibilities of land management support for protecting the natural environment during economic use of northern territories

The article analyzes modern problems of the Arctic zones of the Russian Federation. The characteristics of human economic activity in the northern regions are given. It is shown that the anthropogenic load on the unique nature of the North increases every year. The climatic features of the northern regions, which limit the possibilities of agriculture, are characterized. The main directions for improving reindeer husbandry and organizing the use of reindeer pastures have been developed. It is proposed to grow crops in vertical farms. It has been shown that vertical farms can improve the environmental sustainability of territories and ensure food security

Навигационная биопсия предстательной железы с использованием технологии гистосканирования

The purpose: to evaluate the benefits of targeted prostate biopsy under navigation of the histoscanning technology. Material and methods. During the period from mid- September to December 2013 according to the histoscanning procedure with targeted biopsies were examined 27 patients aged from 47 to 98 years with suspected prostate cancer, aimed at the urology department of “Clinical Hospital №1” of the Presidential Administration of the Russian Federation to perform transrectal prostate multifocal biopsies. All patients underwent complex clinical examination and ultrasound examination, which included: a study in grayscale using ultrasonic angiography, sonoelastography and histoscanning. Results. The sensitivity of histoscanning technology was 81,8%, specificity - 75%, accuracy - 77,7%, PPV - 69,2%, NPV - 85,7% respectively. Conclusion. We can get closer to the new standard of performing prostate biopsy - biopsy of suspicious areas only today.Цель исследования: оценка преимущества таргетной биопсии предстательной железы под навигационным ассистированием с помощью технологии гистосканирования. Материал и методы. За период с середины сентября по декабрь 2013 г по методике гистосканирования с таргетной биопсией было обследовано 27 пациентов в возрасте от 47 до 98 лет с подозрением на рак предстательной железы, направленных в урологическое отделение КБ №1 УД Президента РФ для выполнения трансректальной мультифокальной биопсии предстательной железы. Всем пациентам было выполнено комплексное клиническое обследование и УЗИ, которое включало: исследование в режиме серой шкалы с применением УЗ-ангиографии, соноэластографию и гистосканирование. Результаты. Чувствительность технологии гистосканирования составила 81,8%, специфичность - 75%, точность - 77,7%, прогностичность положительного теста - 69,2%, отрицательного - 85,7%. Заключение. На сегодняшний день возможно приблизиться к новому стандарту биопсии предстательной железы - прицельным биопсиям только подозрительных участков

CRYSTALLIZATION OF SENSES AS A MEANS OF AXIOLOGICAL SYSTEM FORMATION IN THE CYCLE OF STORIES “LEGENDS ABOUT GOD” BY R.M. RILKE

The article is devoted to the study of the process of axiological system formation as the basis of structural and stylistic unity in the cycle of stories "Legends about God" by R.M. Rilke. Using the linguistic and hermeneutic method, contextual analysis, the techniques of sense crystallization identified the metasenses based on the author's key words Hдnde (Hands), Gott (God), Tod (Death). Taking into account the earlier research the author of the article revealed the metasenses of other keywords – Lahme (Paralyzed), Geschichte (History), Kinder (Children), Menschen (People), reconstructed and presented in the form of schematic art space «Legends about God» reflecting axiological installation of R.M. Rilke. The location of keywords representing artistic concepts, indicates the existence of two mirror worlds reflecting each other, the shell of which is Geschichte – a way of life, history. One of the worlds, with top of the generated keyword Kinder, symbolizing freedom and love, unites Gott, Menschen, Tod and Hände linking concepts "Gott" and "Menschen". Another world is expressed by the key words Gott, Menschen, Tod. The edge structure that separates these two worlds is Lahme. The article shows that the content of crystallized concepts is different: in the first world the keyword Gott expresses ideas about personal, sublime and spiritual, Menschen symbolizes spiritually rich people seeking for freedom, Tod is the fruit of life; in the second world Gott is associated with the concept of socially significant things, Menschen symbolizes people who are in constant search for themselves, Tod is intimidating mass death. The author proves the special role of keyword Hände in creating the artistic space of the considered cycle of stories: being a symbol of creativity, beautiful stream, it mediates between the Gott and Menschen and exists only in the first world

ОСНОВОПОЛАГАЮЩИЕ КОНЦЕПТЫ ХУДОЖЕСТВЕННОГО МИРА Р.М. РИЛЬКЕ (НА ПРИМЕРЕ ЦИКЛА РАССКАЗОВ «ИСТОРИИ О ГОСПОДЕ БОГЕ»)

Purpose consists in study of mechanism of forming and realization of concepts and concept sphere in works of R.M. Rilke. As a methodological basis of research it is necessary to consider base positions of the theory of a discourse on the basis of computer communications (N.D. Arutyunova, E.I. Goroshko, E.N. Galichkina, O.V. Voron, E. Goffman, M. Kastels, B.Ju.Gorodetskiy, V.I. Karasik, P.E. Kondrashov), linguistic crystallization (I.P. Tcherkasova, V. Humboldt, A.A. Potebnja). As methodological basis of research it is necessary to examine labours of authors in area of lingvokonceptologii - lingvokul′turologii (S.G. Vorkachev, V.I. Karasik, N.A. Krasavskiy, M.V. Pimenova, G.G. Slyshkin, Ju.S. Stepanov), cognitive linguistics (N.D. Arutyunova, A.P. Babushkin, N.N. Boldyrev, V.Z. Demjankov, E.S. Kubrjakova, Z.D. Popova, I.A. Sternin), psycholinguistics (A.A. Zalevskaja), theories of text and artistic semantics (N.F. Alefirenko, L.G. Babenko, M.M. Bakhtin, L. Bugaeva, I.R. Galperin), base positions of hermeneutics (G.I. Bogin, I.A. Vorobey, V.P. Litvinov, I.G. Tkachenko, I.P. Tcherkasova). In the paper used linguistic-hermeneutic method based on the method of «hermeneutical circle» by G. Gadamer, methods and schemes of the reader in understanding the meaning by G. Bogin, the method of text analysis by R. Bart and the concordance. The scientific novelty of this work is to identify and model the individual author’s concepts R.M. Rilke in their relationships and interactions. The work describes the art of concept sphere R.M. Rilke (based on cycle of stories, «Stories of God») as a result of individual author’s thinking. Results: the paper considers the language units that presenting artistic concepts of R.M. Rilke; interpretation of the use of these units is offered in a context; a design comes true integral structure of authorial concept sphere. The results of the work are depicted schematically. Practical implications: conclusions and research materials can be applied by preparation lecture and a practical training under the cognitive semantic, by creating training manuals on linguistic analysis of a literary text.Цель исследования заключается в изучении механизма формирования и реализации концептов и концептосферы в произведениях Р.М. Рильке. В качестве методологической основы исследования следует рассматривать труды отечественных и зарубежных авторов в области лингвоконцептологии - лингвокультурологии (С.Г. Воркачев, В.И. Карасик, Н.А. Красавский, В.П. Нерознак, М.В. Пименова, Г.Г. Слышкин, Ю.С. Степанов), когнитивной лингвистики (Н.Д. Арутюнова, А.П. Ба-бушкин, Н.Н. Болдырев, А. Вежбицкая, В.З. Демьянков, Е.С. Кубрякова, З.Д. Попова, И.А. Стернин), психолингвистики (А.А. Залевская), теории текста и художественной семантики (Н.Ф. Алефиренко, Л.Г. Бабенко, М.М. Бахтин, Л. Бугаева, И.Р. Гальперин), базовые положения герменевтики (Г.И. Богин, И.А. Воробей, В.П. Литвинов, И.Г. Ткаченко, И.П. Черкасова). В работе использовался лингвистико-герменевтический метод, базирующийся на методе «герменевтического круга», разработанном Г. Гадамером, методике и схемах действий читателя при понимании смысла Г.И. Богина, методе текстового анализа Р. Барта и методе конкор-данса. Научная новизна работы заключается в выявлении и моделировании индивидуально-авторских концептов Р.М. Рильке в их взаимосвязи и взаимодействии. В работе дано описание художественной концептосферы Р.М. Рильке (на основе цикла рассказов «Истории о Господе Боге») как результата индивидуально-авторского мышления. Результаты: в работе выделяются языковые единицы, репрезентирующие художественные концепты Р.М. Рильке, предлагается интерпретация употребления данных единиц в контексте, осуществляется моделирование целостной структуру авторской концептосферы (изображено схематически). Область применения результатов: выводы и материалы исследования могут быть применены при подготовке лекционных и практических занятий в учебных курсах по когнитивной семантике, лингвокультурологии, при создании учебных пособий по лингвистическому анализу художественного текста

Winter hard wheat in Kursk Region

Kursk Federal Agricultural Research Center, together with National Grain Center named after P.P. Lukyanenko, has been studying and selecting hybrid populations, lines and varieties of hard winter wheat since 2012. Since 2017, they have been studied for ecological plasticity and the presence of economically valuable features when cultivating in the Central Chernozem Region (Kursk Region) varieties of winter hard wheat bred by FSBSI “Agricultural Research Center “Donskoy”on the basis of agreements on creative and scientific cooperation. At this stage of research, a large number of seedlings of winter hard wheat were tested, of which the most promising ones were identified. Using highly effective methods of ecological selection and having worked out breeding material in the environmental breeding laboratory of Kursk FARC, research data for 2018-2020. on yield, resistance to creep, overwintering, crop structure (height of plants, number of plants, number of stems, number of productive stems, total bush, productive bush, mass of 1000 grains, length of main spike, number of grains in main spike, weight of grain from one plant) and grain quality, on the basis of which grades and lines of winter hard wheat are evaluated. Over the years of research, weather conditions have developed in a variety of ways. Adverse environmental factors made it possible to better assess the level of adaptability of the studied sorto samples to abiostresses. In this regard an important task of joint breeding, is to increase environmental sustainability, the ability to ensure high stable yields in the soil and climatic conditions of the cultivation region

High calories but not fat content of lard-based diet contribute to impaired mitochondrial oxidative phosphorylation in C57BL/6J mice heart

PURPOSE: High calorie intake leads to obesity, a global socio-economic and health problem, reaching epidemic proportion in children and adolescents. Saturated and monounsaturated fatty acids from animal (lard) fat are major components of the western-pattern diet and its regular consumption leads to obesity, a risk factor for cardiovascular disease. However, no clear evidence exists whether consumption of diet rich in saturated (SFAs) and monounsaturated (MUFAs) fatty acids has detrimental effects on cardiac structure and energetics primarily due to excessive calories. We, therefore, sought to determine the impact of high calories versus fat content in diet on cardiac structure and mitochondrial energetics. METHODS: Six-week-old C57BL/6J mice were fed with high calorie, high lard fat-based diet (60% fat, HFD), high-calorie and low lard fat-based diet (10% fat, LFD), and lower-calorie and fat diet (standard chow, 12% fat, SCD) for 10 weeks. RESULTS: The HFD- and LFD-fed mice had higher body weight, ventricular mass and thickness of posterior and septal wall with increased cardiomyocytes diameter compared to the SCD-fed mice. These changes were associated with a reduction in the mitochondrial oxidative phosphorylation (OXPHOS) complexes I and III activity compared to the SCD-fed mice without significant differences between the HFD- and LFD-fed animals. The HFD-fed animals had higher level of malondialdehyde (MDA) than LFD and SCD-fed mice. CONCLUSIONS: We assume that changes in cardiac morphology and selective reduction of the OXPHOS complexes activity observed in the HFD- and LFD-fed mice might be related to excessive calories with additional effect of fat content on oxidative stress