Etiologic diagnosis of pleural effusion by punch biopsy of the parietal pleura

Needle biopsy of the pleura using Harefield pleural biopsy punch, has been performed in 100 subjects, 58 of whom were 40 years of age or over, in order to arrive at a histologic diagnosis. Ancillary investigations such as bronchoscopy and lymph node biopsy have been done where necessary and feasible. In 18 of the 58 in the older age group and in 15 of the 42 in the younger age group, the biopsy showed lesions suggestive of tuberculous infection; 13 in the older age group and two in the other showed evidence of malignancy; 23 in the older and 21 in the younger group showed nonspecific changes. Vegetative forms of Entamoeba histolytica were demonstrated in the biopsy material in one case. Biopsy, performed on one occasion only was a failure in five cases. No untoward effects were noticed as a consequence of the procedure

Systemic donovaniasis

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AN INTRASPINAL DERMOID CYST ASSOCIATED WITH ANOTHER IN THE OVARY

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Effect of heparin on wound healing

Heparin with its ability to dissolve the fibrin clot exerts its major effect in the early stages of wound healing by depriving the fibroblasts of their scaffold. Heparin inhibits cross linking of collagen and accelerates its degradation. There is faulty orientation of the collagen fibrils in the heparinized wound. It may be concluded that heparin interferes with wound healing

A CASE OF INTRAMEDULLARY NEURINOMA

Neurinomas are among the commonest extra-medullary space-occupying lesions encountered in the spinal canal. The occurence of such neoplasms in an intramedullary site, however, is rare and raises interesting questions regarding its mode of origin. For this reason the following instance of intramedullary neurimons is recorded