7 research outputs found

    Just reporting : does the school have a justifiable reporting process?

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    This thesis titled `Just Reporting' aimed to explore the question: Does the school have a justifiable reporting process that meets the needs of key stakeholders (parents, students and teachers)? Through a critical review of the research literature relevant to reporting, various ethical issues were noted that assisted in the construction of the questions guiding this study. These ethical issues provided the lens through which I explored the reporting practices at the research school. The title Just Reporting emphasises the justice issues surrounding reporting as a communicative action where the integrity of each individual is maintained and relationships strengthened. The research took the form of a case study involving the participation of thirty-three parents, eleven teachers and twenty-one students from the one school setting in a questionnaire that had both quantitative and qualitative questions that gathered their affective and cognitive responses to the school's written report. I also held one focus group interview with parents to clarify information from the questionnaire. An interactive inquiry with mixed methods approach was chosen as the best way to answer the research questions. The aim was to develop a theory about reporting rather than prove an existing theory. This study examines what reporting is, the audience and purpose of reporting, and the imperatives of justifiable reporting. It gathered the opinions and beliefs about reporting at the research school from key stakeholder groups and sought to discover whether the written report met their needs and fulfilled the requirements of justifiable reporting. Final analysis of the data provided understandings about the nature of reporting at the research school and revealed a number of issues that prevented the process from being fully justifiable

    In Reply

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    We appreciate the interest of Lagier et al. in our article.1 The authors highlighted in their letter the work of Montaigne et al.,2 who have recently published on the circadian rhythm in relation to ischemia reperfusion injury in a single-center retrospective propensity-matched cohort study addressing this subject on 596 (matched-pairs) patients undergoing aor-tic valve replacement with or without coronary artery bypass grafting, together with a single-center randomized study in 88 patients undergoing isolated aortic valve replacement, in which the perioperative myocardial injury has been assessed with the geometric mean of perioperative cardiac troponin T release

    Effect of xenon anesthesia compared to sevoflurane and total intravenous anesthesia for coronary artery bypass graft surgery on postoperative cardiac troponin release. an international, multicenter, phase 3, single-blinded, randomized noninferiority trial

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    Abstract BACKGROUND: Ischemic myocardial damage accompanying coronary artery bypass graft surgery remains a clinical challenge. We investigated whether xenon anesthesia could limit myocardial damage in coronary artery bypass graft surgery patients, as has been reported for animal ischemia models. METHODS: In 17 university hospitals in France, Germany, Italy, and The Netherlands, low-risk elective, on-pump coronary artery bypass graft surgery patients were randomized to receive xenon, sevoflurane, or propofol-based total intravenous anesthesia for anesthesia maintenance. The primary outcome was the cardiac troponin I concentration in the blood 24 h postsurgery. The noninferiority margin for the mean difference in cardiac troponin I release between the xenon and sevoflurane groups was less than 0.15 ng/ml. Secondary outcomes were the safety and feasibility of xenon anesthesia. RESULTS: The first patient included at each center received xenon anesthesia for practical reasons. For all other patients, anesthesia maintenance was randomized (intention-to-treat: n = 492; per-protocol/without major protocol deviation: n = 446). Median 24-h postoperative cardiac troponin I concentrations (ng/ml [interquartile range]) were 1.14 [0.76 to 2.10] with xenon, 1.30 [0.78 to 2.67] with sevoflurane, and 1.48 [0.94 to 2.78] with total intravenous anesthesia [per-protocol]). The mean difference in cardiac troponin I release between xenon and sevoflurane was -0.09 ng/ml (95% CI, -0.30 to 0.11; per-protocol: P = 0.02). Postoperative cardiac troponin I release was significantly less with xenon than with total intravenous anesthesia (intention-to-treat: P = 0.05; per-protocol: P = 0.02). Perioperative variables and postoperative outcomes were comparable across all groups, with no safety concerns. CONCLUSIONS: In postoperative cardiac troponin I release, xenon was noninferior to sevoflurane in low-risk, on-pump coronary artery bypass graft surgery patients. Only with xenon was cardiac troponin I release less than with total intravenous anesthesia. Xenon anesthesia appeared safe and feasible

    RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up

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