7 research outputs found

    Binding of Ī±vĪ²3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

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    Open Access via Springer Compact Agreement Acknowledgements We are very grateful to Prof. Calderwood (Yale University, USA) for providing the THD DNA construct, Dr. Massimiliano Baldassarre (University of Aberdeen) for useful discussions on integrin regulation and Charlie Taylor for helping to optimise the THD transfection experiments. We thank the NHS Grampian Endowment Fund for funding this research and CRANES and the Roland Sutton Academic Trust for financial support for AA.Peer reviewedPublisher PD

    Design and synthesis of an RGD peptidomimetic-paclitaxel conjugate targeting Ī±vĪ²3 integrin for tumour-directed drug delivery

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    We thank the Development Trust, University of Aberdeen, for funding a fellowship to M.P. and a studentship to A.A. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1590898.Peer reviewedPostprin

    High Affinity ā€œClickā€ RGD Peptidomimetics as Radiolabeled Probes for Imaging Ī±vĪ²3 Integrin

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    We thank The Development Trust, University of Aberdeen, for financial support and a fellowship to M.P. The work was also supported by the CRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester (KJW Co-I; reference 16465). We thank Dr Massimiliano Baldassarre (University of Aberdeen) for helpful discussions.Peer reviewedPostprin

    Early changes in [18F] FDG incorporation by breast cancer cells treated with trastuzumab in normoxic conditions : Role of the Akt-pathway, glucose transport and HIF-1Ī±

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    Acknowledgment The work was funded by the University of Aberdeen and Friends of Anchor. We thank Dr Iain Brown, University of Aberdeen, for the generous gift of the anti-pHER2 antibody.Peer reviewedPostprintPreprin
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