Magma Fracking Beneath Active Volcanoes Based on Seismic Data and Hydrothermal Activity Observations

Active volcanoes are associated with microearthquake (MEQ) hypocenters that form plane-oriented cluster distributions. These are faults delineating a magma injection system of dykes and sills. The Frac-Digger program was used to track fracking faults in the Kamchatka active volcanic belt and fore-arc region of Russia. In the case of magma laterally injected from volcanoes into adjacent structures, high-temperature hydrothermal systems arise, for example at Mutnovsky and Koryaksky volcanoes. Thermal features adjacent to these active volcanoes respond to magma injection events by degassing CO2 and by transient temperature changes. Geysers created by CO2-gaslift activity in silicic volcanism areas also flag magma and CO2 recharge and redistributions, for example at the Uzon-Geyserny, Kamchatka, Russia and Yellowstone, USA magma hydrothermal systems. Seismogenic faults in the Kamchatka fore-arc region are indicators of geofluid fracking; those faults can be traced down to 250 km depth, which is within the subduction slab below primary magma sources

Impact of Allelic Variation in Maturity Genes <i>E1</i>–<i>E4</i> on Soybean Adaptation to Central and West Siberian Regions of Russia

Four maturity genes, namely, E1, E2, E3 and E4, have been found to play major roles in controlling the flowering and maturity time of soybean. Which genotypes of E1–E4 genes provide effective adaptation to the varied conditions of Russia are unknown. To clarify this issue, we have studied the allele variation in soybean E1–E4 genes in terms of both flowering and maturity time under the natural day-length conditions of Central Russia and Western Siberia in a collection of 176 soybean accessions, including 142 Russian and 34 foreign accessions. As a result, a high frequency of previously determined E1–E4 alleles has been identified. The field experiment showed that genotypes with all recessive alleles from e1-nl/e2/e3/e4 and e1-as/e2/e3/e4 provide the effective adaptation of soybean to the mentioned conditions. Cultivars with these genotypes are considered to be most suitable for cultivation in Central Russia and Western Siberia

Isotopes & Geochemistry: Tools For Geothermal Reservoir Characterization (Kamchatka Examples)

The thermal, hydrogeological, and chemical processes affecting Kamchatka geothermal reservoirs were studied by using isotope and geochemistry data: (1) The Geysers Valley hydrothermal reservoirs; (2) The Paratunsky low temperature reservoirs; (3) The North-Koryaksky hydrothermal system; (4) The Mutnovsky high temperature geothermal reservoir; (5) The Pauzhetsky geothermal reservoir. In most cases water isotope in combination with Cl- transient data are found to be useful tool to estimate reservoirs natural and disturbed by exploitation recharge conditions, isotopes of carbon-13 (in CO2) data are pointed either active magmatic recharge took place, while SiO2 and Na-K geothermometers shows opposite time transient trends (Paratunsky, Geysers Valley) suggest that it is necessary to use more complicated geochemical systems of water/mineral equilibria

Effect of Rebamipide on the Intestinal Barrier, Gut Microbiota Structure and Function, and Symptom Severity Associated with Irritable Bowel Syndrome and Functional Dyspepsia Overlap: A Randomized Controlled Trial

Treatment of functional digestive disorders is not always effective. Therefore, a search for new application points for potential drugs is perspective. Our aim is to evaluate the effect of rebamipide on symptom severity, intestinal barrier status, and intestinal microbiota composition and function in patients with diarrheal variant of irritable bowel syndrome overlapping with functional dyspepsia (D-IBSoFD). Sixty patients were randomized to receive trimebutine (TRI group), trimebutine + rebamipide (T + R group), or rebamipide (REB group) for 2 months. At the beginning and end of the study, patients were assessed for general health (SF-36), severity of digestive symptoms (Gastrointestinal Symptom Rating and 7 × 7 scales), state of the intestinal barrier, and composition (16S rRNA gene sequencing) and function (short-chain fatty acid fecal content) of the gut microbiota. The severity of most digestive symptoms was reduced in the REB and T + R groups to levels similar to that observed in the TRI group. The duodenal and sigmoidal lymphocytic and sigmoidal eosinophilic infiltration was decreased only in the REB and T + R groups, not in the TRI group. Serum zonulin levels were significantly decreased only in the REB group. A decrease in intraepithelial lymphocytic infiltration in the duodenum correlated with a decrease in the severity of rumbling and flatulence, while a decrease in infiltration within the sigmoid colon correlated with improved stool consistency and decreased severity of the sensation of incomplete bowel emptying. In conclusion, rebamipide improves the intestinal barrier condition and symptoms in D-IBSoFD. The rebamipide effects are not inferior to those of trimebutine

Bio-hybridization of nanobactericides with cellulose films for effective treatment against members of ESKAPE drug resistant pathogens

The rapid expansion of drug-resistant pathogens has created huge global impact and development of novel antimicrobial leads is one of the top priority studies in the current scenario. The present study aims to develop bio-hybridized nanocellulose films which comprise of phytogenic silver nanobactericides. The nanobactericides were synthesized by treating 1 mM silver nitrate with aqueous extract of Chamerion angustifolium which reduced the metal salt to produce polydispersed nanobactericides which were tested against the members of ESKAPE drug-resistant communities. The synthesized silver nanobactericides were subjected to characterization with UV–visible spectra which displayed maximum absorbance at 408 nm. The bio-molecular interaction of phyto-constituents to mediate synthesis and stabilization of nanobactericides was studied with Fourier-transform infrared spectroscopy (FTIR) which depicted functional groups associated with nanobactericides. The crystalline nature was studied with X-ray diffraction (XRD) which showed Bragg’s intensities at 2θ angle which denoted (111), (200), (220), and (311) planes. The morphological characteristics of silver nanobactericides were defined with transmission electron Microscopy (TEM) image which displayed polydispersity of silver nanobactericides with size ranging from 2 to 40 nm. The synthesized nanobactericides showed a significant activity against MRSA strain with 21 mm zone of inhibition. The minimal inhibitory concentration of silver nanobactericides to inhibit the growth of test pathogens was also determined which ranged between 0.625 and 1.25 μg/ml. The silver nanobactericides were bio-hybridized onto nanocellulose films produced by Komagataeibacter xylinus B-12068 culture strain. The films were dried to determine the mechanical properties which showed increased in Young’s modulus and tensile strength in comparison with control bacterial cellulose films. Overall, the results obtained in the present investigation are promising enough to report bactericidal activity of bio-hybridized nanobactericidal films against ESKAPE. These communities are reported to cause severe threats to all forms of lives irrespective to their habitats which can lead to huge economical crisis