The Athletic Profile of Fast Bowling in Cricket : A Review

Cricket is a global sport played in over 100 countries with elite performers attracting multimillion dollar contracts. Therefore, performers maintaining optimum physical fitness and remaining injury free is important. Fast bowlers have a vital position in a cricket team, and there is an increasing body of scientific literature that has reviewed this role over the past decade. Previous research on fast bowlers has tended to focus on biomechanical analysis and injury prevention in performers. However, this review aims to critically analyze the emerging contribution of physiological-based literature linked to fast bowling in cricket, highlight the current evidence related to simulated and competitive in-match performance, and relate this practically to the conditioning coach. Furthermore, the review considers limitations with past research and possible avenues for future investigation. It is clear with the advent of new applied mobile monitoring technology that there is scope for more ecologically valid and longitudinal exploration capturing in-match data, providing quantification of physiological workloads, and analysis of the physical demands across the differing formats of the game. Currently, strength and conditioning specialists do not have a critical academic resource with which to shape professional practice, and this review aims to provide a starting point for evidence in the specific areaPeer reviewedFinal Accepted Versio

Doing Deals in Japan: An Analysis of Recent Trends & Developments for the U.S. Practitioner

This article examines the process which is currently being played out in Japan by: (i) analyzing the recent changes in Japanese law of relevance to M&A deals, (ii) discussing some recent contested deals in Japan that may shed some light on current market practices, and (iii) providing an overview of the key issues that a U.S. practitioner will likely face when working on a Japanese deal…A good starting point in better understanding the remarkable changes in the Japanese M&A markets is to review the recent amendments to Japanese law, certain policy initiatives by the functional regulators, and other guidelines issued by Japanese government agencies… In concert with the changes in Japanese law, we have seen an increase in the number of contested deals in Japan in recent years…[T]he challenge for the U.S. practitioner is to boil down the complexity of Japanese M&A to a list of key issues that should be reviewed in any transaction which involves Japanese entities…[W]e have set forth some of the main issues under Japanese law and U.S. securities laws that have often come into play in Japanese deals…The current Japanese M&A market presents opportunities for U.S. companies and their advisors that are arguably the most promising in recent history…[G]iven the challenges posed by the opportunities in the Japanese M&A market, the importance of well informed and considered decision-making will be essential in order to ensure that U.S. companies compete and succeed in doing Japanese deals

Screen Time and Executive Function in Toddlerhood: A Longitudinal Study.

Technology is pervasive in homes with young children. Emerging evidence that electronic screen-based media use has adverse effects on executive functions may help explain negative relations between media use and early academic skills. However, longitudinal investigations are needed to test this idea. In a sample of 193 British toddlers tracked from age 2 to 3 years, we test concurrent and predictive relations between screen use and children's executive function. We find no concurrent association between screen use and executive function; however, screen time at age 2 is negatively associated with the development of executive functions in toddlerhood from age 2 to 3, controlling for a range of covariates including verbal ability. Implications for parenting, education, and pediatric recommendations are discussed

Field based reliability and validity of the Bioharness multivariable monitoring device

The BioharnessTM device is designed for monitoring physiological variables in free-living situations but has only been proven to be reliable and valid in a laboratory environment. Therefore, this study aimed to determine the reliability and validity of the BioharnessTM using a field based protocol. Twenty healthy males participated. Heart rate (HR), breathing frequency (BF) and accelerometry (ACC) were assessed by simultaneous measurement of two BioharnessTM devices and a test-retest of a discontinuous incremental walk-jog-run protocol (4 – 11 km·h-1) completed in a sports hall. Adopted precision of measurement devices were; HR: Polar T31 (Polar Electro), BF: Spirometer (Cortex Metalyser), ACC: Oxygen expenditure (Cortex Metalyser). For all data, precision of measurement reported good relationships (r = 0.61 to 0.67, p \u3c 0.01) and large Limits of Agreement for HR (\u3e79.2 b·min-1) and BF (\u3e54.7 br·min-1). ACC presented excellent precision (r = 0.94, p \u3c 0.01). Results for HR (r= ~0.91, p \u3c 0.01: CV \u3c7.6) and ACC (r \u3e 0.97, p \u3c 0.01; CV \u3c14.7) suggested these variables are reliable. BF presented more variable data (r = 0.46-0.61, p \u3c 0.01; CV \u3c 23.7). As velocity of movement increased (\u3e8 km·h-1) data became more erroneous. A data cleaning protocol removed gross errors in the data analysis and subsequent reliability and validity statistics improved across all variables. In conclusion, the BioharnessTM HR and ACC variables have demonstrated reliability and validity in a field setting, though data collected at higher velocities should be treated with caution. Measuring human physiological responses in a field based environment allows for more ecologically valid data to be collected and devices such as the BioharnessTM could be used by exercise professionals to begin to further investigate this area

Field based reliability and validity of the Bioharness multivariable monitoring device

The Bioharness™ device is designed for monitoring physiological variables in free-living situations but has only been proven to be reliable and valid in a laboratory environment. Therefore, this study aimed to determine the reliability and validity of the Bioharness™ using a field based protocol. Twenty healthy males participated. Heart rate (HR), breathing frequency (BF) and accelerometry (ACC) were assessed by simultaneous measurement of two Bioharness™ devices and a test-retest of a discontinuous incremental walk-jog-run protocol (4 - 11 km·h-1) completed in a sports hall. Adopted precision of measurement devices were; HR: Polar T31 (Polar Electro), BF: Spirometer (Cortex Metalyser), ACC: Oxygen expenditure (Cortex Metalyser). For all data, precision of measurement reported good relationships (r = 0.61 to 0.67, p 79.2 b·min-1) and BF (>54.7 br·min-1). ACC presented excellent precision (r = 0.94, p 0.97, p 8 km·h-1) data became more erroneous. A data cleaning protocol removed gross errors in the data analysis and subsequent reliability and validity statistics improved across all variables. In conclusion, the Bioharness™ HR and ACC variables have demonstrated reliability and validity in a field setting, though data collected at higher velocities should be treated with caution. Measuring human physiological responses in a field based environment allows for more ecologically valid data to be collected and devices such as the Bioharness™ could be used by exercise professionals to begin to further investigate this area

Bioharness multivariable monitoring device. Part I: Validity

The BioharnessTM monitoring system may provide physiological information on human performance but there is limited information on its validity. The objective of this study was to assess the validity of all 5 BioharnessTM variables using a laboratory based treadmill protocol. 22 healthy males participated. Heart rate (HR), Breathing Frequency (BF) and Accelerometry (ACC) precision were assessed during a discontinuous incremental (0- 12 km·h-1) treadmill protocol. Infra-red skin temperature (ST) was assessed during a 45 min-1 sub-maximal cycle ergometer test, completed twice, with environmental temperature controlled at 20 ±0.1 °C and 30 ± 0.1 °C. Posture (P) was assessed using a tilt table moved through 160°. Adopted precision of measurement devices were; HR: Polar T31 (Polar Electro), BF: Spirometer (Cortex Metalyser), ACC: Oxygen expenditure (Cortex Metalyser), ST: Skin thermistors (Grant Instruments), P:Goniometer (Leighton Flexometer). Strong relationships (r = .89 to .99, p \u3c 0.01) were reported for HR, BF, ACC and P. Limits of agreement identified differences in HR (-3.05±32.20 b·min-1), BF (-3.46 ± 43.70 br·min-1) and P (0.20 ± 2.62°). ST established a moderate relationships (-0.61 ± 1.98 °C; r = 0.76, p \u3c 0.01). Higher velocities on the treadmill decreased the precision of measurement, especially HR and BF. Global results suggest that the BioharressTM is a valid multivariable monitoring device within the laboratory environment

Bioharness multivariable monitoring device. Part II: Reliability

The BioharnessTM monitoring system may provide physiological information on human performance but the reliability of this data is fundamental for confidence in the equipment being used. The objective of this study was to assess the reliability of each of the 5 BioharnessTM variables using a treadmill based protocol. 10 healthy males participated. A between and within subject design to assess the reliability of Heart rate (HR), Breathing Frequency (BF), Accelerometry (ACC) and Infra-red skin temperature (ST) was completed via a repeated, discontinuous, incremental treadmill protocol. Posture (P) was assessed by a tilt table, moved through 160o. Between subject data reported low Coefficient of Variation (CV) and strong correlations(r) for ACC and P (CV\u3c 7.6; r = 0.99, p \u3c 0.01). In contrast, HR and BF (CV~19.4; r~0.70, p \u3c 0.01) and ST (CV 3.7; r = 0.61, p \u3c 0.01), present more variable data. Intra and inter device data presented strong relationships (r \u3e 0.89, p \u3c 0.01) and low CV

Worrying in the Wings: Negative Emotional Birth Memories in Mothers and Fathers Show Similar Associations with Perinatal Mood Disturbance and Delivery Mode

Abstract Background: Negative birth experiences are associated with symptoms of post-traumatic stress disorder in new mothers but have received much less attention in new fathers. Methods: A sample of 322 first-time expectant couples (196 in the UK and 126 in the USA) rated their symptoms of anxiety and depression in the third trimester and at 4-months post birth (234 natural delivery, 88 caesarean section), when they also completed the emotional memories subscale of the BirthMARQ (Foley, Crawley, Wilkie, & Ayers, 2014). We first examined parent gender, mode of delivery (natural birth versus caesarean section) and study site (UK versus USA) as predictors of BirthMARQ scores. Next, we applied Actor-Partner-Interdependence-Modelling (APIM) to investigate intra- and interpersonal associations between birth experiences and latent factors for antenatal and postnatal depression/anxiety in both mothers and fathers. Results: Reports of negative birth experiences were more common for mothers than fathers, for parents of babies born by caesarean section than vaginal delivery and for UK parents than for USA parents. Within-couple agreement was moderately strong and individual differences in negative birth memories were associated with latent factors for depression/anxiety at both time-points, for both parents; in addition, there was a marginal mediation effect of negative birth memories in relation to the association between birth via caesarean section and reduced postnatal maternal wellbeing. Conclusions: Our findings highlight the links between birth experiences and wellbeing for both mothers and fathers and so support the development of partner-inclusive intervention strategies. Key words: birth experience, depression, anxiety, mothers, fathers, deliveryThe research was funded by grants from the Economic and Social Research Council and National Science Foundation (ESRC: ES/ L016648/1 and NSF: 1429152)

Serum vitamin D levels, diabetes and cardio-metabolic risk factors in Aboriginal and Torres Strait Islander Australians

Assesses levels of serum 25(OH)D in Aboriginal and Torres Strait Islander Australians and explores relationships between 25(OH)D and cardio-metabolic risk factors and diabetes. Abstract Background: Low levels of serum 25 – hydroxy vitamin D (25(OH)D), have been associated with development of type 2 diabetes and cardiovascular disease (CVD); however there are limited data on serum 25(OH)D in Indigenous Australians, a population at high risk for both diabetes and CVD. We aimed to assess levels of serum 25(OH)D in Aboriginal and Torres Strait Islander Australians and to explore relationships between 25(OH)D and cardio-metabolic risk factors and diabetes. Methods: 592 Aboriginal and/or Torres Strait Islander Australian participants of The eGFR (estimated glomerular filtration rate) Study, a cross-sectional analysis of a cohort study performed in 2007 – 2011, from urban and remote centres within communities, primary care and tertiary hospitals across Northern Territory, Far North Queensland and Western Australia. Assessment of serum 25(OH)D, cardio-metabolic risk factors (central obesity, diabetes, hypertension, history of cardiovascular disease, current smoker, low HDL-cholesterol), and diabetes (by history or HbA1c ≥ 6.5%) was performed. Associations were explored between 25(OH)D and outcome measures of diabetes and number of cardio-metabolic risk factors. Results: The median (IQR) serum 25(OH)D was 60 (45 – 77) nmol/L, 31% had 25(OH)D <50 nmol/L. For participants with 25(OH)D < 50 vs ≥ 50 nmol/L, cardio-metabolic risk profile differed for: diabetes (54%, 36% p < 0.001), past history of cardiovascular disease (16%, 9%, p = 0.014), waist-hip ratio (0.98, 0.92, p < 0.001), urine albumin-creatinine ratio (2.7, 1.5 mg/mmol, p < 0.001). The OR (95% CI) for diabetes was 2.02 (1.03 – 3.95) for people in the lowest vs highest tertiles of 25(OH)D (<53 vs >72 nmol/L, respectively) after adjusting for known cardio-metabolic risk factors. Conclusion: The percentage of 25(OH)D levels <50 nmol/L was high among Aboriginal and Torres Strait Islander Australians from Northern and Central Australia. Low 25(OH)D level was associated with adverse cardio-metabolic risk profile and was independently associated with diabetes. These findings require exploration in longitudinal studies

Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo susceptibility to artemisinin and chloroquine in Plasmodium berghei

As resistance to artemisinins (current frontline drugs in malaria treatment) emerges in south East Asia, there is an urgent need to identify the genetic determinants and understand the molecular mechanisms underpinning such resistance. Such insights could lead to prospective interventions to contain resistance and prevent the eventual spread to other malaria endemic regions. Artemisinin reduced susceptibility in South East Asia (SEA) has been primarily linked to mutations in P. falciparum Kelch-13, which is currently widely recognised as a molecular marker of artemisinin resistance. However, 2 mutations in a ubiquitin hydrolase, UBP-1, have been previously associated with artemisinin reduced susceptibility in a rodent model of malaria and some cases of UBP-1 mutation variants associating with artemisinin treatment failure have been reported in Africa and SEA. In this study, we have employed CRISPR-Cas9 genome editing and pre-emptive drug pressures to test these artemisinin susceptibility associated mutations in UBP-1 in P. berghei sensitive lines in vivo. Using these approaches, we have shown that the V2721F UBP-1 mutation results in reduced artemisinin susceptibility, while the V2752F mutation results in resistance to chloroquine and moderately impacts tolerance to artemisinins. Genetic reversal of the V2752F mutation restored chloroquine sensitivity in these mutant lines while simultaneous introduction of both mutations could not be achieved and appears to be lethal. Interestingly, these mutations carry a detrimental growth defect, which would possibly explain their lack of expansion in natural infection settings. Our work has provided independent experimental evidence on the role of UBP-1 in modulating parasite responses to artemisinin and chloroquine under in vivo conditions