Introduction. Ruptures in the Everyday

Ruptures in the Everyday was jointly written by ATG26, a scholarly collective comprising the following authors:Jonathan Bach, Andrew Stuart Bergerson (lead author), Susanne Beer, Mark E. Blum, Michaela Christ, Cristina Cuevas-Wolf, Mary Fulbrook, Eva Giloi, Thomas Gurr, Jason Johnson, Craig Koslofsky, Dani Kranz, Phil Leask, Wendy Lower, Elissa Mailänder, Josie McLellan, Alexandra Oeser, Steve Ostovich, Will Rall, Leonard Schmieding (lead author), Johannes Schwartz, Sara Ann Sewell, Paul Steege, Maximilian Strnad, Julia Timpe, Heléna TóthInternational audienc

USACE Section 206 Ecosystem Restoration Program and Development of Restoration Alternatives to Support Projects in Cobb County, Georgia

Proceedings of the 2003 Georgia Water Resources Conference, held April 23-24, 2003, at the University of Georgia.The Mobile District of the U.S. Army Corps of Engineers (USACE) is currently pursuing ecosystem restoration opportunities in the Atlanta Metropolitan Area in accordance with the USACE Aquatic Ecosystem Restoration Program authorized by Section 206 of the Water Resources Development Act of 1996 (Section 206). The Atlanta Metropolitan Area continues to grow at a rapid rate. This rapid growth has led to numerous water resources problems, including: 1) increased stormwater volume and peak discharges; 2) increased flooding; 3) accelerated erosion; 4) stream bed lowering; 5) diminished water quality; and 6) degraded aquatic habitat. The following paragraphs will describe the USACE Continuing Authorities Program (CAP), the Section 206 Program, the USACE study process, the development of ongoing Section 206 projects in Cobb County, Georgia and their status

War, Exile, Justice, and Everyday Life, 1936-1946

Millions of Europeans experienced war, occupation, and exile in the turbulent years between the outbreak of the Spanish Civil War in 1936 and the end of World War II in 1946. The contributors to this volume focus on the lives of ordinary people ensnared in world events beyond their control. Well-known landmark events like the bombing of Gernika, the mass exile following the Spanish Civil War, France’s sudden defeat in 1940 and its subsequent occupation by Germany, the French resistance, and the Allied invasion of France and liberation come to light through the people involved in them: A Tyrolean German soldier trying to make a life and ignore (and explain away) the difficult realities of his regime, Eastern European, mainly Jewish, resisters in occupied Paris, Basque nationalist priests persecuted by Franco regime, children exiled from their homes living in French and other refugee camps, even American newspaper readers. These are the unlikely protagonists in history that is usually seen from the top down, but here is explored from the bottom up.This book focuses on the lives of ordinary people ensnared in world events of the 1930s and 1940s beyond their control such as the bombing of Gernika, Spanish Civil War exile, France’s sudden defeat and its occupation and more.This book was published with generous financial support from the Basque Goverment

BTK drives neutrophil activation for sterilizing antifungal immunity

We describe a previously-unappreciated role for Bruton's tyrosine kinase (BTK) in fungal immune surveillance against aspergillosis, an unforeseen complication of BTK inhibitors (BTKi) used for treating B-cell lymphoid malignancies. We studied BTK-dependent fungal responses in neutrophils from diverse populations, including healthy donors, BTKi-treated patients, and X-linked agammaglobulinemia patients. Upon fungal exposure, BTK was activated in human neutrophils in a TLR2-, Dectin-1-, and FcγR-dependent manner, triggering the oxidative burst. BTK inhibition selectively impeded neutrophil-mediated damage to Aspergillus hyphae, primary granule release, and the fungus-induced oxidative burst by abrogating NADPH oxidase subunit p40phox and GTPase RAC2 activation. Moreover, neutrophil-specific Btk deletion in mice enhanced aspergillosis susceptibility by impairing neutrophil function, not recruitment or lifespan. Conversely, GM-CSF partially mitigated these deficits by enhancing p47phox activation. Our findings underline the crucial role of BTK signaling in neutrophils for antifungal immunity and provide a rationale for GM-CSF use to offset these deficits in susceptible patients