193 research outputs found
Reconstructing signed relations from interaction data
Positive and negative relations play an essential role in human behavior and
shape the communities we live in. Despite their importance, data about signed
relations is rare and commonly gathered through surveys. Interaction data is
more abundant, for instance, in the form of proximity or communication data. So
far, though, it could not be utilized to detect signed relations. In this
paper, we show how the underlying signed relations can be extracted with such
data. Employing a statistical network approach, we construct networks of signed
relations in four communities. We then show that these relations correspond to
the ones reported in surveys. Additionally, the inferred relations allow us to
study the homophily of individuals with respect to gender, religious beliefs,
and financial backgrounds. We evaluate the importance of triads in the signed
network to study group cohesion.Comment: 14 pages, 3 figures, submitte
Forest Conservation and CO2 Emissions : A Viable Approach.
We adopt viability theory to assess the sustainability of the world’s forests while taking into account some of the competing economic, social, and environmental uses of these forests, namely, timber production, poverty alleviation through agriculture, and air quality as well as the negative externalities that these uses create. We provide insights on the different trade-offs faced to achieve sustainability and draw some policy implications as to what is the path leading to sustainability in the long run.Emissions; Forest; Sustainability; Viability theory;
Neuron-Specific Regulation of Associative Learning and Memory by MAGI-1 in C. elegans
Background: Identifying the molecular mechanisms and neural circuits that control learning and memory are major challenges in neuroscience. Mammalian MAGI/S-SCAM is a multi-PDZ domain synaptic scaffolding protein that interacts with a number of postsynaptic signaling proteins and is thereby thought to regulate synaptic plasticity [1,2,3]. Principal Findings: While investigating the behavioral defects of C. elegans nematodes carrying a mutation in the single MAGI ortholog magi-1, we have identified specific neurons that require MAGI-1 function for different aspects of associative learning and memory. Various sensory stimuli and a food deprivation signal are associated in RIA interneurons during learning, while additional expression of MAGI-1 in glutamatergic AVA, AVD and possibly AVE interneurons is required for efficient memory consolidation, i.e. the ability to retain the conditioned changes in behavior over time. During associative learning, MAGI-1 in RIA neurons controls in a cell non-autonomous fashion the dynamic remodeling of AVA, AVD and AVE synapses containing the ionotropic glutamate receptor (iGluR) GLR-1 [4]. During memory consolidation, however, MAGI-1 controls GLR-1 clustering in AVA and AVD interneurons cell-autonomously and depends on the ability to interact with the b-catenin HMP-2. Significance: Together, these results indicate that different aspects of associative learning and memory in C. elegans are likely carried out by distinct subsets of interneurons. The synaptic scaffolding protein MAGI-1 plays a critical role in thes
Modeling social resilience: Questions, answers, open problems
Resilience denotes the capacity of a system to withstand shocks and its
ability to recover from them. We develop a framework to quantify the resilience
of highly volatile, non-equilibrium social organizations, such as collectives
or collaborating teams. It consists of four steps: (i) \emph{delimitation},
i.e., narrowing down the target systems, (ii) \emph{conceptualization}, .e.,
identifying how to approach social organizations, (iii) formal
\emph{representation} using a combination of agent-based and network models,
(iv) \emph{operationalization}, i.e. specifying measures and demonstrating how
they enter the calculation of resilience. Our framework quantifies two
dimensions of resilience, the \emph{robustness} of social organizations and
their \emph{adaptivity}, and combines them in a novel resilience measure. It
allows monitoring resilience instantaneously using longitudinal data instead of
an ex-post evaluation
Thirty Years of heavy Fermions: Scientific Setting for their Discovery and Partial Understanding
Heavy-Fermions provide an extreme example of the utility of the idea of
continuity and analyticity in physics. Their discovery and study in the past
thirty years has added a fascinating chapter to condensed matter physics. I
briefly review the origins of the heavy-fermion problem out of the study of
magnetic moments in metals and the study of mixed-valent rare-earth compounds.
I also review the principal ideas underlying the features understood in their
fermi-liquid phase as well as in their anisotropic superconductivity. The
unsolved issues are also briefly mentioned.Comment: This is the text of one of the talks given at the plenary symposium
entitled "Thirty years of heavy Fermions" at the beginning of the
International conference on Strongly correlated Electrons in Vienna in July
200
Characterizing Ionospheric Effects on GNSS Reflectometry at Grazing Angles from Space
Coherent observations in GNSS reflectometry are prominent in regions with smooth reflecting surfaces and at grazing elevation angles. However, within these lower elevation ranges, GNSS signals traverse a more extensive atmospheric path, and increased ionospheric effects (e.g., delay biases) are expected. These biases can be mitigated by employing dual-frequency receivers or models tailored for single-frequency receivers. In preparation for the single-frequency GNSS-R ESA “PRETTY” mission, this study aims to characterize ionospheric effects under variable parameter conditions: elevation angles in the grazing range (5° to 30°), latitude-dependent regions (north, tropic, south) and diurnal changes (day and nighttime). The investigation employs simulations using orbit data from Spire Global Inc.’s Lemur-2 CubeSat constellation at the solar minimum (F10.7 index at 75) in March 2021. Changes towards higher solar activity are accounted for with an additional scenario (F10.7 index at 180) in March 2023. The electron density associated with each reflection event is determined using the Neustrelitz Electron Density Model (NEDM2020) and the NeQuick 2 model. The results from periods of low solar activity reveal fluctuations of up to approximately 300 TECUs in slant total electron content, 19 m in relative ionospheric delay for the GPS L1 frequency, 2 Hz in Doppler shifts, and variations in the peak electron density height ranging from 215 to 330 km. Sea surface height uncertainty associated with ionospheric model-based corrections in group delay altimetric inversion can reach a standard deviation at the meter level
Thermodynamic properties of the periodic Anderson model:X-boson treatment
We study the specific dependence of the periodic Anderson Model (PAM) in the
limit of employing the X-boson treatment in two fifferent regimes of
the PAM: the heavy fermion Kondo (HF-K) and the heavy fermion local magnetic
regime (HF-LMM). We obtain a multiple peak structure for the specific heat in
agreement with experimental results as well as the increase of the electronic
effective mass at low temperatures associated with the HF-K regime. The entropy
per site at low T tends to zero in the HF-K regime, corresponding to a singlet
ground state, and it tends to in the HF-LMM, corresponding to a
doublet ground state at each site. The linear coefficient
of the specific heat qualitatively agrees with the experimental results
obtained for differents materials in the two regimes considered here.Comment: 9 pages, 14 figure
Airborne Coherent GNSS Reflectometry and Zenith Total Delay Estimation over Coastal Waters
High-precision GNSS (global navigation satellite e system) measurements can be used for remote sensing and nowadays play a significant role in atmospheric sounding (station data, radio occultation observations) and sea surface altimetry based on reflectometry. A limiting factor of high-precision reflectometry is the loss of coherent phase information due to sea-state-induced surface roughness. This work studies airborne reflectometry observations recorded over coastal waters to examine the sea-state influence on Doppler distribution and the coherent residual phase retrieval. From coherent observations, the possibility of zenith total delay inversion is also investigated, considering the hydrostatic mapping factor from the Vienna mapping function and an exponential vertical decay factor depending on height receiver changes. The experiment consists of multiple flights performed along the coast between the cities of Calais and Boulogne-sur-Mer, France, in July 2019. Reflected signals acquired in a right-handed circular polarization are processed through a model-aided software receiver and passed through a retracking module to obtain the Doppler and phase-corrected signal. Results from grazing angle observations (elevation < 15°) show a high sensitivity of Doppler spread with respect to sea state with correlations of 0.75 and 0.88 with significant wave height and wind speed, respectively. An empirical Doppler spread threshold of 0.5 Hz is established for coherent reflections supported by the residual phase observations obtained. Phase coherence occurs in 15% of the observations; however, the estimated zenith total delay for the best event corresponds to 2.44 m, which differs from the typical zenith total delay (2.3 m) of 5%
Complex interaction between dengue virus replication and expression of miRNA-133a
Background: Dengue virus (DENV) is the most common vector-borne viral infection worldwide with approximately 390 million cases and 25,000 reported deaths each year. MicroRNAs (miRNAs) are small non-coding RNA molecules responsible for the regulation of gene expression by repressing mRNA translation or inducing mRNA degradation. Although miRNAs possess antiviral activity against many mammalian-infecting viruses, their involvement in DENV replication is poorly understood. Methods: Here, we explored the relationship between DENV and cellular microRNAs using bioinformatics tools. We overexpressed miRNA-133a in Vero cells to test its role in DENV replication and analyzed its expression using RT-qPCR. Furthermore, the expression of polypyrimidine tract binding protein (PTB), a protein involved in DENV replication, was analyzed by western blot. In addition, we profiled miRNA-133a expression in Vero cells challenged with DENV-2, using Taqman miRNA. Results: Bioinformatic analysis revealed that the 3' untranslated region (3'UTR) of the DENV genome of all four DENV serotypes is targeted by several cellular miRNAs, including miRNA-133a. We found that overexpression of synthetic miRNA-133a suppressed DENV replication. Additionally, we observed that PTB transcription, a miRNA-133a target, is down-regulated during DENV infection. Based in our results we propose that 3' UTR of DENV downregulates endogenous expression of miRNA-133a in Vero cells during the first hours of infection. Conclusions: miRNA-133a regulates DENV replication possibly through the modulation of a host factor such as PTB. Further investigations are needed to verify whether miRNA-133a has an anti-DENV effect in vivo
Orbital state and magnetic properties of LiV_2 O_4
LiV_2 O_4 is one of the most puzzling compounds among transition metal oxides
because of its heavy fermion like behavior at low temperatures. In this paper
we present results for the orbital state and magnetic properties of LiV_2 O_4
obtained from a combination of density functional theory within the local
density approximation and dynamical mean-field theory (DMFT). The DMFT
equations are solved by quantum Monte Carlo simulations. The trigonal crystal
field splits the V 3d orbitals such that the a_{1g} and e_{g}^{pi} orbitals
cross the Fermi level, with the former being slightly lower in energy and
narrower in bandwidth. In this situation, the d-d Coulomb interaction leads to
an almost localization of one electron per V ion in the a_{1g} orbital, while
the e_{g}^{pi} orbitals form relatively broad bands with 1/8 filling. 2The
theoretical high-temperature paramagnetic susceptibility chi(T) follows a
Curie-Weiss law with an effective paramagnetic moment p_{eff}=1.65 in agreement
with the experimental results.Comment: 11 pages, 10 figures, 2 table
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