ASPECTS REGARDING THE ENERGITICAL VALORIFICATION OF URBAN SLUDGE TREATMENT

This paper highlights through the issues addressed, the application aspects regarding the approach of the concept of recovery of sewage sludge from an urban wastewater treatment plant (SEAU), which is in a stage of technological expansion and modernization. Thus, it is considered the need to process the potential of biological mass generated by anaerobic stabilization in the SEAU, with a population of about 10,000 equivalent inhabitants, which requires on one hand, the technological design of activated sludge basins and on the other hand, the design of a sewage sludge fermentation tank, in order to produce biogas, necessary for its recovery for energy purposes

Safety of Antibiotics in Hospitalized Children in Romania: A Prospective Observational Study

Antibiotics are among the most prescribed drugs in pediatric inpatients and are frequently associated with adverse drug reactions (ADRs) in children. This study aimed to assess the frequency and type of ADRs related to the use of antibiotics in pediatric inpatients through a prospective observational study, conducted over 6 months, covering the winter and spring seasons when the incidence of infections peaks in Romania. ADRs were evaluated for causality, avoidability and severity. Among the 266 included children, 25 (9.4%) experienced 30 ADRs. ADR frequency tended to be higher in ≤2-year-olds (13 of 25, 52.0%) than in other age categories. Gastrointestinal and hematological ADRs were most frequently observed. Diarrhea was the most common ADR associated with antibiotics (8 of 30, 26.7%). Ceftriaxone (16 of 30, 53.3%), cefuroxime, ceftazidime and azithromycin (3 of 30, 10.0% each) were most commonly responsible for ADRs. After causality assessment, 2 (6.7%) ADRs were considered definite, 12 (40.0%) probable and 16 (53.3%) possible. One ADR was classified as definitely avoidable and one as possibly avoidable. Seven children required treatment for ADRs. Antibiotic treatment was discontinued in 4 children. Antibiotics frequently caused ADRs in ≤ 2-year-olds and were commonly associated with gastrointestinal symptoms. Close monitoring of antibiotic-associated ADRs remains important in the pediatric population