Green Approach Extraction of Perezone from the Roots of Acourtia platyphilla (A. Grey): A Comparison of Four Activating Modes and Supercritical Carbon Dioxide

Perezone, a sesquiterpene quinone, is a very important molecule due to its pharmacological activities in addition to the fact that it is considered to be the first secondary metabolite isolated in the new world (America–Mexico, 1852). This study aims to offer a green comparative study about the extraction of the target molecule from the roots of the vegetable specimen Acourtia platyphilla (A. Grey). The study was performed comparing five different modes of extraction: supercritical CO2, electromagnetic infrared and microwave irradiations, mechanical-wave ultrasound versus typical mantle heating procedure. An exhaustive comparative-discussion of the obtained results is provided. It is worth noting that the corresponding quantifications were established using 1H NMR, correlating appropriately the integrals of the vinylic proton H-6 of perezone with the aromatic singlet of p-dinitrobenzene employed as an internal reference. It is also important to highlight that the four presented procedures are novel modes to extract perezone. Finally, a complementary study about the solubility of the target sesquiterpene quinone related to the use of supercritical CO2 is also reported

Education in Sustainable Chemistry and its relation to the Sustainable Development Goals

En el proyecto se propone la realización de trabajos en grupo dirigidos a los alumnos de Química General de 1º en los que se desarrollen los principios de la Química Sostenible y se relacionen con los Objetivos de Desarrollo Sostenible. Las mejores presentaciones serán grabadas en video para su difusión.The project proposes group work for 1st year General Chemistry students in which the principles of Sustainable Chemistry are developed and related to the Sustainable Development Goals. The best presentations will be recorded on video for dissemination.Fac. de Ciencias QuímicasFALSEsubmitte