1,111 research outputs found
Parity-violating asymmetry in with a pionless effective theory
Nuclear parity violation is studied with polarized neutrons in the
photodisintegration of the deuteron at low energies. A pionless effective field
theory with di-baryon fields is used for the investigation. Hadronic weak
interactions are treated by parity-violating di-baryon-nucleon-nucleon
vertices, which have undetermined coupling contants. A parity-violating
asymmetry in the process is calculated for the incident photon energy up to 30
MeV. If experimental data for the parity-violating asymmetry become available
in the future, we will be able to determine the unknown coupling contants in
the parity-violating vertices.Comment: 4 pages. A contribution to APFB2011, August 22-26, 2011, Seoul, Kore
Tau phosphorylation at Alzheimer\u27s disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.
Abnormal phosphorylation of the microtubule-associated protein tau is observed in many neurodegenerative diseases, including Alzheimer\u27s disease (AD). AD-related phosphorylation of two tau residues, Ser262 and Ser356, by PAR-1/MARK stabilizes tau in the initial phase of mismetabolism, leading to subsequent phosphorylation events, accumulation, and toxicity. However, the relative contribution of phosphorylation at each of these sites to tau stabilization has not yet been elucidated. In a Drosophila model of human tau toxicity, we found that tau was phosphorylated at Ser262, but not at Ser356, and that blocking Ser262 phosphorylation decreased total tau levels. By contrast, when PAR-1 was co-overexpressed with tau, tau was hyperphosphorylated at both Ser262 and Ser356. Under these conditions, the protein levels of tau were significantly elevated, and prevention of tau phosphorylation at both residues was necessary to completely suppress this elevation. These results suggest that tau phosphorylation at Ser262 plays the predominant role in tau stabilization when PAR-1/MARK activity is normal, whereas Ser356 phosphorylation begins to contribute to this process when PAR-1/MARK activity is abnormally elevated, as in diseased brains
Low energy proton-proton scattering in effective field theory
Low energy proton-proton scattering is studied in pionless effective field
theory. Employing the dimensional regularization and MS-bar and power
divergence subtraction schemes for loop calculation, we calculate the
scattering amplitude in 1S0 channel up to next-to-next-to leading order and fix
low-energy constants that appear in the amplitude by effective range
parameters. We study regularization scheme and scale dependence in separation
of Coulomb interaction from the scattering length and effective range for the
S-wave proton-proton scattering.Comment: 23 pages, 6 eps figures, revised considerably, accepted for
publication in Phys. Rev.
Identification and Radiofrequency Catheter Ablation of a Nonsustained Atrial Tachycardia at the Septal Mitral Annulus with the Use of a Noncontact Mapping System: A Case Report
AbstractHere we report a case of a 16-year old female with symptomatic nonsustained atrial tachycardia (NSAT) originating from the septal mitral annulus. NSAT was induced by atrial burst pacing after an intravenous isoproterenol (ISP) injection. The array mode of the noncontact mapping system (NCM) allowed us to quickly identify the tachycardia focus at the septal mitral annulus, where the contact bipolar voltage map revealed no low voltage area (<0.5 mV). The NSAT was eliminated by a radiofrequency energy application to the identified tachycardia focus during sinus rhythm, and the patient has been free from any symptoms during 10 months of follow-up
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