Quantum measurements of atoms using cavity QED

Generalized quantum measurements are an important extension of projective or von Neumann measurements, in that they can be used to describe any measurement that can be implemented on a quantum system. We describe how to realize two non-standard quantum measurements using cavity quantum electrodynamics (QED). The first measurement optimally and unabmiguously distinguishes between two non-orthogonal quantum states. The second example is a measurement that demonstrates superadditive quantum coding gain. The experimental tools used are single-atom unitary operations effected by Ramsey pulses and two-atom Tavis-Cummings interactions. We show how the superadditive quantum coding gain is affected by errors in the field-ionisation detection of atoms, and that even with rather high levels of experimental imperfections, a reasonable amount of superadditivity can still be seen. To date, these types of measurement have only been realized on photons. It would be of great interest to have realizations using other physical systems. This is for fundamental reasons, but also since quantum coding gain in general increases with code word length, and a realization using atoms could be more easily scaled than existing realizations using photons.Comment: 10 pages, 5 figure

General K=-1 Friedman-Lema\^itre models and the averaging problem in cosmology

We introduce the notion of general K=-1 Friedman-Lema\^itre (compact) cosmologies and the notion of averaged evolution by means of an averaging map. We then analyze the Friedman-Lema\^itre equations and the role of gravitational energy on the universe evolution. We distinguish two asymptotic behaviors: radiative and mass gap. We discuss the averaging problem in cosmology for them through precise definitions. We then describe in quantitative detail the radiative case, stressing on precise estimations on the evolution of the gravitational energy and its effect in the universe's deceleration. Also in the radiative case we present a smoothing property which tells that the long time H^{3} x H^{2} stability of the flat K=-1 FL models implies H^{i+1} x H^{i} stability independently of how big the initial state was in H^{i+1} x H^{i}, i.e. there is long time smoothing of the space-time. Finally we discuss the existence of initial "big-bang" states of large gravitational energy, showing that there is no mathematical restriction to assume it to be low at the beginning of time.Comment: Revised version. 32 pages, 1 figur

The unintegrated gluon distribution from the CCFM equation

The gluon distribution f(x, k_t^2,mu^2), unintegrated over the transverse momentum k_t of the gluon, satisfies the angular-ordered CCFM equation which interlocks the dependence on the scale k_t with the scale \mu of the probe. We show how, to leading logarithmic accuracy, the equation can be simplified to a single scale problem. In particular we demonstrate how to determine the two-scale unintegrated distribution f(x,k_t^2,mu^2) from knowledge of the integrated gluon obtained from a unified scheme embodying both BFKL and DGLAP evolution.Comment: 16 pages LaTeX, 3 eps figure

Azimuthal decorrelation of forward and backward jets at the Tevatron

We analyse the azimuthal decorrelation of Mueller-Navelet dijets produced in the collisions at Tevatron energies using a BFKL framework which incorporates dominant subleading effects. We show that these effects significantly reduce the decorrelation yet they are still insufficient to give satisfactory description of experimental data. However a good description of the data is obtained after incorporating within formalism the effective rapidity defined by Del Duca and Schmidt.Comment: 1+9 pages, 6 eps figures; the final version to appear in Phys. Lett. B; one reference added, the use of effective rapidity and the need for BFKL resummmation for small azimuthal angles better motivate

Linking the Resource Description Framework to cheminformatics and proteochemometrics

<p>Abstract</p> <p>Background</p> <p>Semantic web technologies are finding their way into the life sciences. Ontologies and semantic markup have already been used for more than a decade in molecular sciences, but have not found widespread use yet. The semantic web technology Resource Description Framework (RDF) and related methods show to be sufficiently versatile to change that situation.</p> <p>Results</p> <p>The work presented here focuses on linking RDF approaches to existing molecular chemometrics fields, including cheminformatics, QSAR modeling and proteochemometrics. Applications are presented that link RDF technologies to methods from statistics and cheminformatics, including data aggregation, visualization, chemical identification, and property prediction. They demonstrate how this can be done using various existing RDF standards and cheminformatics libraries. For example, we show how IC₅₀ and K<it>_i</it> values are modeled for a number of biological targets using data from the ChEMBL database.</p> <p>Conclusions</p> <p>We have shown that existing RDF standards can suitably be integrated into existing molecular chemometrics methods. Platforms that unite these technologies, like Bioclipse, makes this even simpler and more transparent. Being able to create and share workflows that integrate data aggregation and analysis (visual and statistical) is beneficial to interoperability and reproducibility. The current work shows that RDF approaches are sufficiently powerful to support molecular chemometrics workflows.</p

Legal geographies of irregular migration : An outlook on immigration detention

In this article, I discuss legal geographies of irregular migration, drawing on a case study on immigration detention in Finland. Based on analysis of detention records, four different types of legal geographies are identified, relating to south–north movement of third‐country nationals inside Europe, criminalised Eastern European EU citizens, irregularity during the asylum process (in particular, related to the Dublin Regulation) and irregularly residing foreign nationals, including deportable long‐term residents. The analysis focuses on the relations between space, law and persons during detainees' irregular migration trajectories, paying attention to their varying entry routes, residence times, legal grounds for removal and detention and removal countries. I argue for the need for empirically contextualised analysis that addresses the complex relations between law and geography beyond a particular national context, in order to better understand the dynamics of irregular migration in all its variety.In this article, I discuss legal geographies of irregular migration, drawing on a case study on immigration detention in Finland. Based on analysis of detention records, four different types of legal geographies are identified, relating to south–north movement of third‐country nationals inside Europe, criminalised Eastern European EU citizens, irregularity during the asylum process (in particular, related to the Dublin Regulation) and irregularly residing foreign nationals, including deportable long‐term residents. The analysis focuses on the relations between space, law and persons during detainees' irregular migration trajectories, paying attention to their varying entry routes, residence times, legal grounds for removal and detention and removal countries. I argue for the need for empirically contextualised analysis that addresses the complex relations between law and geography beyond a particular national context, in order to better understand the dynamics of irregular migration in all its variety.Peer reviewe

MAOA haplotypes associated with thrombocyte-MAO activity

BACKGROUND: The aim was to ascertain whether thrombocyte MAO (trbc-MAO) activity and depressed state are genetically associated with the MAO locus on chromosome X (Xp11.3 – 11.4). We performed novel sequencing of the MAO locus and validated genetic variants found in public databases prior to constructing haplotypes of the MAO locus in a Swedish sample (N = 573 individuals). RESULTS: Our results reveal a profound SNP desert in the MAOB gene. Both the MAOA and MAOB genes segregate as two distinct LD blocks. We found a significant association between two MAOA gene haplotypes and reduced trbc-MAO activity, but no association with depressed state. CONCLUSION: The MAO locus seems to have an effect on trbc-MAO activity in the study population. The findings suggest incomplete X-chromosome inactivation at this locus. It is plausible that a gene-dosage effect can provide some insight into the greater prevalence of depressed state in females than males

Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer

A microfluidic mixer is applied to study the kinetics of calmodulin conformational changes upon Ca2+ binding. The device facilitates rapid, uniform mixing by decoupling hydrodynamic focusing from diffusive mixing and accesses time scales of tens of microseconds. The mixer is used in conjunction with multiphoton microscopy to examine the fast Ca2+-induced transitions of acrylodan-labeled calmodulin. We find that the kinetic rates of the conformational changes in two homologous globular domains differ by more than an order of magnitude. The characteristic time constants are ≈490 μs for the transitions in the C-terminal domain and ≈20 ms for those in the N-terminal domain of the protein. We discuss possible mechanisms for the two distinct events and the biological role of the stable intermediate, half-saturated calmodulin

The non-forward BFKL amplitude and rapidity gap physics

We discuss the BFKL approach to processes with large momentum transferred through a rapidity gap. The Mueller and Tang scheme to the BFKL non-forward parton-parton elastic scattering amplitude at large $t$, is extended to include higher conformal spins. The new contributions are found to decrease with increasing energy, as follows from the gluon reggeisation phenomenon, and to vanish for asymptotically high energies. However, at moderate energies and high $|t|$, the higher conformal spins dominate the amplitude. We illustrate the effects by studying the production of two high $E_T$ jets separated by a rapidity gap at HERA energies. In a simplified framework, we find excellent agreement with the HERA photoproduction data once we incorporate the rapidity gap survival probability against soft rescattering effects. We emphasize that measurements of the analogous process in electroproduction may probe different summations over conformal spins.Comment: Latex, 14 pages, 3 figures; the final version to appear in Phys. Lett. B; a short discussion of the Tevatron data added; a previously missing factor of i^n introduced in eq. (13