1,278 research outputs found
Bibliography of Indonesian publications: newspapers, non-government periodicals and bulletins, 1945-1958, at Cornell University
Data Paper: Number 33. Total number of pages: 69 p
Oral and intravenous bretylium disposition
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109931/1/cptclpt1980190.pd
Determining Success or Failure After Foot and Ankle Surgery Using Patient Acceptable Symptom State (PASS) and Patient Reported Outcome Information System (PROMIS)
Background: As the role of generic patient-reported outcomes (PROs) expands, important questions remain about their interpretation. In particular, how the Patient Reported Outcome Measurement Instrumentation System (PROMIS) t score values correlate with the patients’ perception of success or failure (S/F) of their surgery is unknown. The purposes of this study were to characterize the association of PROMIS t scores, the patients’ perception of their symptoms (patient acceptable symptom state [PASS]), and determination of S/F after surgery.
Methods: This retrospective cohort study contacted patients after the 4 most common foot and ankle surgeries at a tertiary academic medical center (n = 88). Patient outcome as determined by phone interviews included PASS and patients’ judgment of whether their surgery was a S/F. Assessment also included PROMIS physical function (PF), pain interference (PI), and depression (D) scales. The association between S/F and PASS outcomes was evaluated by chi-square analysis. A 2-way analysis of variance (ANOVA) evaluated the ability of PROMIS to discriminate PASS and/or S/F outcomes. Receiver operator curve (ROC) analysis was used to evaluate the ability of pre- (n = 63) and postoperative (n = 88) PROMIS scores to predict patient outcomes (S/F and PASS). Finally, the proportion of individuals classified by the identified thresholds were evaluated using chi-square analysis.
Results: There was a strong association between PASS and S/F after surgery (chi-square \u3c0.01). Two-way ANOVA demonstrated that PROMIS t scores discriminate whether patients experienced positive or negative outcome for PASS (P \u3c .001) and S/F (P \u3c .001). The ROC analysis showed significant accuracy (area under the curve \u3e 0.7) for postoperative but not preoperative PROMIS t scores in determining patient outcome for both PASS and S/F. The proportion of patients classified by applying the ROC analysis thresholds using PROMIS varied from 43.0% to 58.8 % for PASS and S/F.
Conclusions: Patients who found their symptoms and activity at a satisfactory level (ie, PASS yes) also considered their surgery a success. However, patients who did not consider their symptoms and activity at a satisfactory level did not consistently consider their surgery a failure. PROMIS t scores for physical function and pain demonstrated the ability to discriminate and accurately predict patient outcome after foot and ankle surgery for 43.0% to 58.8% of participants. These data improve the clinical utility of PROMIS scales by suggesting thresholds for positive and negative patient outcomes independent of other factors.
Level of Evidence: II, prospective comparative series
Precision Astrometry with Adaptive Optics
We investigate the limits of ground-based astrometry with adaptive optics
using the core of the Galactic globular cluster M5. Adaptive optics systems
provide near diffraction-limit imaging with the world's largest telescopes. The
substantial improvement in both resolution and signal-to-noise ratio enables
high-precision astrometry from the ground. We describe the dominant systematic
errors that typically limit ground-based differential astrometry, and enumerate
observational considerations for mitigating their effects. After implementing
these measures, we find that the dominant limitation on astrometric performance
in this experiment is caused by tilt anisoplanatism. We then present an optimal
estimation technique for measuring the position of one star relative to a grid
of reference stars in the face of this correlated random noise source. Our
methodology has the advantage of reducing the astrometric errors as the square
root of time and faster than the square root of the number of reference stars
-- effectively eliminating noise caused by atmospheric tilt to the point that
astrometric performance is limited by centering accuracy. Using 50 reference
stars we demonstrate single-epoch astrometric precision of ~ 1 mas in 1 second,
decreasing to < 100 microarcseconds in 2 minutes of integration time at the
Hale 200-inch telescope. We also show that our astrometry is accurate to <~ 100
microarcseconds for observations separated by 2 months. Finally, we discuss the
limits and potential of differential astrometry with current and next
generation large aperture telescopes. At this level of accuracy, numerous
astrometric applications become accessible, including planet detection,
astrometric microlensing signatures, and kinematics of distant Galactic stellar
populations.Comment: 32 pages, 12 figures; submitted to A
Radiation from the extremal black holes
The radiation from extreme Reissner-Nordstr\"{o}m black holes is computed by
explicitly considering the collapse of a spherical charged shell. No neutral
scalar radiation is found but there is emission of charged particles, provided
the charge to mass ratio be different from one. The absence of thermal effects
is in accord with the predictions of the euclidean theory but since the body
emits charged particles the entropy issue is not the same as for eternal
extreme black holes.Comment: 4 pages, LaTex, no figure
Tail States in a Superconductor with Magnetic Impurities
A field theoretic approach is developed to investigate the profile and
spectrum of sub-gap states in a superconductor subject to a weak magnetic
impurity potential. Such states are found to be associated with inhomogeneous
supersymmetry broken instanton configurations of the action.Comment: 4 pages, 2 eps figure
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