Platform trials

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.</p

Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials:A Scoping Review

This upload contains the final datasets analyzed in the manuscript "Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review", published in Critical Care Medicine, 2022 (https://doi.org/10.1097/CCM.0000000000005637). The Supplemental Digital Content included with the primary manuscript includes a data dictionary, additional details, and the analysis code used

Data for "Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review"

This upload contains the final datasets analyzed in the manuscript "Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review", published in Critical Care Medicine, 2022 (https://doi.org/10.1097/CCM.0000000000005637). The Supplemental Digital Content included with the primary manuscript includes a data dictionary, additional details, and the analysis code used