175 research outputs found

    Investors’ Biases & Stock Return Volatility: A Systematic Literature Review

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    Purpose: Literature is scarce on the possible relationship between investors’ biases, risk tolerance attitude, and stock return volatility. The researcher investigated what are the investor biases, and how they contribute to the risk-averse and risk-seeking attitudes and developed a taxonomy model of investors’ biases in the form of a causal framework that impacts stock return volatility. Methodology: The study employs a systematic literature review approach. The analysis of literature includes 65 articles from impact factor journals including three seminal papers in the fields of traditional and behavioral finance. The time frame ranges from 2008 to 2022. Findings: The findings suggest that investors encounter certain biases such as cognitive, emotional, cultural, religious, financial, macroeconomic, demographic, etc. Literature has identified positive, negative, and mixed impacts of investors' biases on stock return volatility. The systematic analysis of literature helps in identifying recently evolving biases such as individualism, uncertainty avoidance, a religious adherence, investor mood, weather bias, fear sentiments, sports sentiments, power distance, masculinity, social media sentiments so on and so forth. Conclusion: The study has proposed an integrated taxonomy model comprised of possible investors’ biases as independent variables along with mediating, controlling, and moderating variables that impact stock return volatility. Moreover, investors’ risk tolerance profile is also constructed which indicates the role of behavioral biases in shaping investors’ attitudes as risk seekers and risk-averse

    Constructing a new mixed probability distribution with fuzzy reliability estimation

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    This paper deals with constructing mixed probability distribution from mixing exponential (β) and Rayleigh along with β. Accordingly, the mixing proportions are ( α/(α+1) ) and ( 1/(α+1) ).At that point, the mixed PDF and CDF were investigated in this study. The mixed reliability has determined based on estimating its two parameters (α,β) by three different methods, which are maximum likelihood, moments and percentiles method. The fuzzy reliability estimators are compared and the results of comparison are explained based on simulation procedure with detailed tables

    Comparison of adverse effects in the treatment of pulmonary hypertension with monotherapy and combination therapy

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    Background: Pulmonary arterial hypertension (PAH) is a serious condition characterized by an increase in pulmonary vascular resistance (PVR) that leads to right heart failure and death. The study aimed to compare the side effects of monotherapy and combination therapy in the treatment of pulmonary hypertensionMethods: This randomized control trial study was conducted at the department of pediatric cardiology, Bangabandhu Sheikh Mujib medical university, national institute of cardiovascular disease, and national heart foundation, Dhaka, Bangladesh. The study duration was 1 year, from January 2018 to December 2018. During this period, a total of 70 participants were selected for the study following the inclusion, and exclusion criteria from those diagnosed case of pulmonary hypertension with congenital heart disease admitted to the pediatric cardiology department, Bangabandhu Sheikh Mujib medical university, NICVD, NHF.Result: Maximum patients had ventricular septal defects (VSD) (34.3% in group A, and 28.6% in group B). Followed by AVSD. 20.0% in group A and 25.7% in group B. Atrial septal defect (ASD) were 14.3% in group A, and 17.1% in group B. After three, and 6 months of follow-up SpO2 per exercise, 6MWD, SpO2 post-exercise, and alanine aminotransferase showed statistically significant differences between single and combined groups. There was no statistically significant difference regarding adverse effects between the 2 groups, but group B patients had slightly higher incidence of some side effects. PASP was significantly decreased in combined group than monotherapy group.Conclusions: This study concludes that combination therapy is more successful than monotherapy in PAH with coronary heart disease (CHD). Our findings demonstrate that combining Bosentan with oral Sildenafil medication in patients with CHD-related PAH is safe, and well tolerated at 3-, and 6-month follow-ups, resulting in a significant improvement in clinical status, effort SpO2, exercise tolerance, hemodynamics, and PASP

    Comparison of short-term outcome between monotherapy versus combination therapy in the treatment of pulmonary hypertension associated with congenital heart disease

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    Background: Pulmonary arterial hypertension (PAH) is a severe condition marked by a progressive rise in pulmonary vascular resistance (PVR), which leads to right heart failure, and mortality. Combining medications is an appealing approach for treating PAH patients. The current study sought to compare the outcomes of monotherapy, and combination therapy after a short period of follow-up. The study aimed to compare the short-term outcome of monotherapy and combination therapy in the treatment of pulmonary hypertension.Methods: This randomized control trial study was conducted at the department of pediatric cardiology, Bangabandhu Sheikh Mujib medical university, national institute of cardiovascular disease, and national heart foundation, Dhaka, Bangladesh, from January 2018 to December 2018. During this period, a total of 70 participants were selected for the study following the inclusion, and exclusion criteria. The selected participants were then divided into two groups of 35 each through random selection.Result: There were no significant differences between the two groups in terms of mean age, and sex. The 34.3% in Group A, and 28.6% in group B had ventricular septal defects (VSD, followed by AVSD at 20.0% in group A and 25.7% in Group B. After 3 and 6 months of follow-up SpO2 per exercise, 6MWD, SpO2 post-exercise, and alanine aminotransferase showed statistically significant differences between single and combined groups. There was no statistically significant difference regarding adverse effects between the two groups. PASP was significantly decreased in the combined group than monotherapy group.Conclusions: Combination therapy is more successful than monotherapy in PAH with CHD. Combining bosentan with oral sildenafil medication in patients with CHD-related PAH is safe, and well tolerated at follow-ups

    Protein Prenylation in the moss Physcomitrium patens

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    Protein prenylation is the addition of a 15 or 20 carbon lipid to a cysteine near carboxyl terminus of target proteins. Prenylation increases hydrophobicity, which facilitates membrane associations and protein-protein interaction. Protein prenylation is generally conserved among eukaryotes, and mutations in genes that carry out prenylation are lethal in animals and yeast. In plants prenylation mutations are not always lethal, but they do affect development, disease resistance, biofuel production, and drought response, among other processes of agricultural interest. To understand the evolutionary and developmental implications of plant protein prenylation, we used the sequenced, annotated, and translated genome of the moss Physcomitrium patens to search for proteins that meet minimal criteria for prenylation; specifically the presence of a sequence that includes cysteine and one of six specific amino acids at the C terminus. We then analyzed these proteins with an online prenylation prediction program to assess their likelihood of being prenylated based on additional sequence motifs. We then determined potential biological function of putative target proteins by using BLAST sequence similarity searches to identify related genes with known function. We plan to use these data to select prenylated proteins with functions of interest for in vivo studies using genetic and molecular tools to investigate their roles in plant development and environmental response. REFERENCES http://www.jbc.org/cgi/doi/10.1074/jbc.M115.673491https://ir.library.louisville.edu/uars/1051/thumbnail.jp

    Investors’ Biases & Stock Return Volatility: A Systematic Literature Review

    Get PDF
    Purpose: Literature is scarce on the possible relationship between investors’ biases, risk tolerance attitude, and stock return volatility. The researcher investigated what are the investor biases, and how they contribute to the risk-averse and risk-seeking attitudes and developed a taxonomy model of investors’ biases in the form of a causal framework that impacts stock return volatility. Methodology: The study employs a systematic literature review approach. The analysis of literature includes 65 articles from impact factor journals including three seminal papers in the fields of traditional and behavioral finance. The time frame ranges from 2008 to 2022. Findings: The findings suggest that investors encounter certain biases such as cognitive, emotional, cultural, religious, financial, macroeconomic, demographic, etc. Literature has identified positive, negative, and mixed impacts of investors' biases on stock return volatility. The systematic analysis of literature helps in identifying recently evolving biases such as individualism, uncertainty avoidance, a religious adherence, investor mood, weather bias, fear sentiments, sports sentiments, power distance, masculinity, social media sentiments so on and so forth. Conclusion: The study has proposed an integrated taxonomy model comprised of possible investors’ biases as independent variables along with mediating, controlling, and moderating variables that impact stock return volatility. Moreover, investors’ risk tolerance profile is also constructed which indicates the role of behavioral biases in shaping investors’ attitudes as risk seekers and risk-averse

    Rehabilitation of Mandibular Dentition Under Conscious Sedation in A Pediatric Patient: a case report

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    Behavior management of younger children during dental treatment always has been a major challenging task for a pediatric dentist. The requirement of advanced behavior guidance techniques in the management of lacking cooperative behavior child is undeniable. Conscious sedation is considered to be one of the best suitable methods for delivering dental treatment in younger children. The procedure exhibits multiple advantages like extensive treatment in a single visit, aids in delivering optimum dental treatment, and prevention of developing psyche of a child. The combined use of pharmacological agents increases the potency of sedation as well as is associated with an analgesic, anxiolytic and amnestic effect. This report represents the first dental pediatric conscious sedation case in Bangladesh in 5.5 years old, anxious, and lacking cooperative behavior child

    Smoking and blood pressure levels in hypertensive patients: evaluating the role of gender, age and hypertension duration

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    Background: Hypertension is estimated to affect about 40% of adults above 25 years of age globally. While many of the risk factors of hypertension are well known, such is not the case with smoking. Pertinent published literature is heterogeneous, with a dearth of relevant local data. Objectives was to study the relationship between smoking and blood pressure levels in hypertensive patients and to assess the effects of gender, age and hypertension duration on such a relationship.Methods: A cross-sectional study was carried out on a total of 298 conveniently sampled patients, aged 18 or above, from the medical outpatient department of a secondary care hospital of Karachi. The relevant data were collected by means of a structured questionnaire whereas the blood pressure level was checked using sphygmomanometer with stethoscope. Mann Whitney U test was used for inferential analysis whereas the significance level was set at 0.05.Results: Overall, both the systolic and diastolic blood pressure levels were significantly associated with smoking history (p<0.05 for both) where they were found to be higher in smokers than in non-smokers. Furthermore, after gender, age and hypertension duration based stratifications; both the systolic and diastolic blood pressure levels were still significantly associated with smoking history in patients who were male, were ≥35 years old and had <5 years hypertension duration (p<0.05 for both) where they were again found to be higher in smokers than in non-smokers.Conclusions: The study results showed a significant association of positive smoking history with higher mean systolic and diastolic blood pressure levels, though after stratifying for gender, age and hypertension duration, this relationship persisted only in patients who were male, were ≥35 years old and had <5 years hypertension duration
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