2 research outputs found

    Influencia de la medicación antiepiléptica sobre los resultados escolares de niños epilépticos

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    Con el objetivo de conocer la influencia de la medicación antiepiléptica sobre los resultados escolares se estudiaron 30 niños que padecen crisis epilépticas parciales y que asisten a escuelas primarias normales. En entrevista familiar se recogió: medicación antiepiléptica usada, dosis en sangre y resultados académicos del último curso escolar que se correlacionó con las variables estudiadas con el test de correlación múltiple. El 80 % (24 niños) recibió tratamiento en monoterapia y 6 (20 %) politerapia. La fenitoína correlacionó significativamente (p < 0,005) con los resultados escolares M. Existe relación de los niveles elevados de droga en sangre con los peores resultados académicos.<br>With the aim of knowing the influence of antiepileptic drug therapy on learning outcomes, 30 children with partial epileptic crisis that go to normal primary schools, were studied. These data were collected in family interviews: antiepileptic drug therapy used, dose in blood, and academic outcomes in the last school course correlated with the variables studied with the multiple correlation test. Twenty four children (80 %) received monotherapy treatment, and six (20 %) received politherapy. Phenytoin significantly correlated (p < 0.005) with M school outcomes. There is a relation of the increased drug levels in blood with the worst academic results

    Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study

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    Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis. Methods: The Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic. Results: Of 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X-ray plus molecular testing (PCR) being the commonest (19\ub78 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6\ub76 and 2\ub74 per cent respectively before, but 23\ub77 and 5\ub73 per cent, during the pandemic (both P < 0\ub7001). One-third changed their approach from laparoscopic to open surgery owing to the popular (but evidence-lacking) advice from expert groups during the initial phase of the pandemic. No agreement on how to filter surgical smoke plume during laparoscopy was identified. There was an overall reduction in the number of patients admitted with appendicitis and one-third felt that patients who did present had more severe appendicitis than they usually observe. Conclusion: Conservative management of mild appendicitis has been possible during the pandemic. The fact that some surgeons switched to open appendicectomy may reflect the poor guidelines that emanated in the early phase of SARS-CoV-2
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