A Review of Orthodontic Archwires

Today more than hundred years have passed since Dr Edward angle placed his first archwire into a patient’s mouth and orthodontics began. It was during that period many innovations did occur that have been explained in terms of art. As time passed scientifically based orthodontics evolved and we see from that time much new innovation in material science have sum uped with new treatment approach and modalities. However, when we turn around and see the  developments and innovations in the material science, we stand with pride: but the urge to make treatment still more comfortable and less time consuming, have led us to the introduction of a plethora of new orthodontic materials and products that represent significant improvement over their predecessors. This article compiles allarchwire from angle era till recent available newer archwire

Medium optimization for the production of lipstatin by Streptomyces toxytricini using full factorial design of experiment

Abstract: Full factorial design of experiment for medium optimization was employed for lipstatin production by Streptomyces toxytricini in shake flask study. The full factorial DOE was very much effective in screening of nutritional parameters within the stipulated time frame in a limited number of experiments. A maximum lipstatin production was achieved 3.290 g/l with the following optimized factors: soya flour 35g/l and soya oil 25g/l. Validation experiments were also carried out to verify the adequacy and the accuracy of the model. The results also give a scope for large scale fermentation of lipstatin production. [Luthra, U., Kumar, H., Kulshreshtha, N., Tripathi, A., Trivedi, A., Khadpekar, S., Chaturvedi, A. and Dubey, R.C. Medium optimization for the production of lipstatin by Streptomyces toxytricini using full factorial design of experiment. Nat Sci 2013;1