653 research outputs found
The Prevalence of the Female Athlete Triad in Division 1 Athletes
The Female Athlete Triad (FAT) is characterized by three individualized disorders that are present at the same time. Low energy availability with or without disordered eating, amenorrhea, and osteoporosis are the three components that make up the Female Athlete Triad. Due to the competitive nature and extreme exercise expenditure of female athletes at the Division 1 level, it is likely that these females are at a higher risk of experiencing the components of the Female Athlete Triad.https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1031/thumbnail.jp
Riding in silence: a little snowboarding, a lot of small RNAs
The recent symposium, RNA silencing: Mechanism, Biology and Applications, organized by Phillip D. Zamore (University of Massachusetts Medical School) and Beverly Davidson (University of Iowa), and held in Keystone, Colorado, brought together scientists working on diverse aspects of RNA silencing, a field that comprises a multitude of gene regulatory pathways guided by microRNAs, small interfering RNAs and PIWI-interacting RNAs
Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion.
Control of human cytomegalovirus (HCMV) depends on CD8+ T cell responses that are shaped by an individual's repertoire of MHC molecules. MHC class I presentation is modulated by a set of HCMV-encoded proteins. Here we show that HCMV immunoevasins differentially impair T cell recognition of epitopes from the same viral antigen, immediate-early 1 (IE-1), that are presented by different MHC class I allotypes. In the presence of immunoevasins, HLA-A- and HLA-B-restricted T cell clones were ineffective, but HLA-C*0702-restricted T cell clones recognized and killed infected cells. Resistance of HLA-C*0702 to viral immunoevasins US2 and US11 was mediated by the alpha3 domain and C-terminal region of the HLA heavy chain. In healthy donors, HLA-C*0702-restricted T cells dominated the T cell response to IE-1. The same HLA-C allotype specifically protected infected cells from attack by NK cells that expressed a corresponding HLA-C-specific KIR. Thus, allotype-specific viral immunoevasion allows HCMV to escape control by NK cells and HLA-A- and HLA-B-restricted T cells, while the virus becomes selectively vulnerable to an immunodominant population of HLA-C-restricted T cells. Our work identifies a T cell population that may be of particular efficiency in HCMV-specific immunotherapy
Mechanics of Ball Striking
https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1020/thumbnail.jp
The Effects of Caffeine on The Agility T-Test and Heart Rate
It was hypothesized that caffeine will increase speed and agility, and increase resting heart rate.https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1061/thumbnail.jp
A Correlational Study of Resting Metabolic Rate
In this experiment, four young adults with various anthropometric measurements completed RMR tests. The purpose of this experiment is to find to what extent RMR increases in relation to FFM, BMI, height and weight. It is hypothesized that a higher RMR is associated with a higher FFM, and RMR will not indicate a strong correlation with the other variables.https://digitalcommons.gardner-webb.edu/exercise-science-research-proposal-posters/1021/thumbnail.jp
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