9 research outputs found
CONSTITUENTS OF BYRSONIMA-CRASSIFOLIA AND THEIR SPASMOGENIC ACTIVITY
No full textIn a biological and phytochemical study on the leaves of Byrsonima crassifolia, 22 compounds were isolated and identified from a MeOH extract. Among the isolates were six triterpenes (betulinaldehyde, betulin, betulinic acid, lupeol, oleanolic acid, and ursenaldehyde), two sterols (beta-sitosterol and its glucoside, six flavonoids (catechin, epicatechin, guaijaverin, hyperin, quercetin and its 3-0-[6''-galloyl]galactoside), an aromatic ester (methyl gallate), four common amino acids (alanine, aspartic acid, proline, and valine), two non-protein amino acids (pipecolic acid and 5-hydroxypipecolic acid), and a novel sulfonoglycolipid. Biological evaluations showed that five of these compounds (betulin, betulinic acid, hyperin, quercetin, and ursenaldehyde) exhibited spasmogenic activity on isolated rat fundus, and three isolates (hyperin, pipecolic acid and 5-hydroxypipecolic acid) showed noncompetitive antagonism to serotonin (5-HT) on the same preparation
Isolation and Structure Determination of Sulfonoquinovosyl Dipalmitoyl Glyceride, a P-Selectin Receptor Inhibitor from the Alga Dictyochloris fragrans
No full textA Preliminary Study of Drug Abuse and Its Mental Health and Health Consequences Among Addicts in Greater Accra, Ghana
No full textSome observations and comments on the psychosocial profile of first-ever referrals to the psychiatric hospital, Enugu, Nigeria
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