As Relações entre espaço e maternidade em Quarto de despejo: diário de uma favelada, de Carolina Maria de Jesus

This article analyzes the connections between the concepts of space and maternity in "Child Of The Dark: The Diary Of Carolina Maria De Jesus" (2014). This study uncovers, through a narrative analysis approach, the relations between space and the portrayal of maternity by the narrator-character of the work. In addition, the construction of the character of Carolina is also scrutinized, observing the sociocultural perspective in the narrative space and demonstrating the intrinsic relations between this space and the context of formation of the maternal subject. The concepts of topoanalysis (Borges Filho, 2007), fictional characters (Cândido, 2009), identity (Hall, 2006), maternity and mothering (Gradvohl; Osis; Makuch, 2014) serve as the theoretical-methodological framework for this research. The impact of space on the character's behavior was noticed, including her relationships with her children, neighbors, and herself. Although the narrator-character's negative relationship with the space in which most of the narrative takes place, it was precisely this relations that drove her to be a nurturing and protective mother for her children, establishing a strong emotional bond with them, transcending maternity and reaching motherhood.Neste artigo, analisaram-se as relações entre espaço e maternidade em Quarto de despejo: diário de uma favelada, de Carolina Maria de Jesus (2014). Neste estudo, buscou-se demonstrar, por meio da análise da narrativa, as relações entre espaço e representação da maternidade encenada pela narradora-personagem da referida obra. Além disso, investigou-se a construção da personagem Carolina, observando-se sobretudo a perspectiva sociocultural no espaço narrativo e demonstrando as intrínsecas relações entre esse espaço e o contexto de formação desse sujeito materno. Para a realização desta pesquisa, serviram de norte teórico-metodológico os conceitos de topoanálise (BORGES FILHO, 2007), de personagem de ficção (CANDIDO, 2009), de identidade (HALL, 2006), assim como os de maternidade e maternagem (GRADVOHL; OSIS; MAKUCH, 2014). Observou-se a interferência do espaço no comportamento da personagem, considerando também as relações que ela mantinha com seus filhos, com seus vizinhos e consigo mesma. Embora a narradora-personagem mantivesse uma relação negativa com o espaço onde ocorre a maior parte da narrativa, é justamente essa relação que a impulsionava a ser uma mãe provedora e protetora para seus filhos, estabelecendo com eles um forte vínculo afetivo, ou seja, indo além da maternidade e alcançando a maternagem

Medication-Related Osteonecrosis of the Jaw and Low-Level Laser Therapy as Adjuvant Treatment: A Case Report

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) occurs by the use of a drug that has osteonecrosis as one of its side effects.Case Report: We describe a case of a 48-year-old oncological patient who had brain and bone metastasis due to breast cancer and was medicated with bisphosphonates (BPs). She presented cavities, and after an incorrect exodontia, the lesion evolved into jaw osteonecrosis. Then she did a sequestrectomy and was treated using laser therapy. Radiological and clinical features are also described.Conclusion: In a case like this, we notice how necessary is a complete evaluation of the oncological patient before some procedures and laser therapy as an effective ally in the management

Can 0.5% Sodium Hypochlorite Treat Candida-Associated Denture Stomatitis?

Objective: To evaluate a 0.5% sodium hypochlorite (SH) protocol in reducing Candida spp. levels in complete dentures (CD) and palate and denture stomatitis (DS) remission. Material and Methods: Twelve CD wearers diagnosed with Candida-associated denture stomatitis (CADS) had their initial situation (Candidaspp. levels and DS score) recorded (baseline). Then, participants were instructed to soak dentures once a day (10 minutes) in 0.5% SH. Candida spp. levels and DS scores were reassessed after 15, 30, and 60 days of SH denture cleanness. Biofilms from the denture base and palate were seeded in CHROMagar Candida. After incubation, colony-forming units were calculated. The palate was photographed at each time point, and DS was assessed according to Newton\u27s classification. Data of Candida spp. levels were analyzed by 2-way repeated measures ANOVA followed by the Holm-Sidak test, and DS scores data were accessed by Friedman\u27s 2-way ANOVA by ranks (α=0.05). Results: 0.5% SH significantly reduced Candida spp. levels after treatment compared to baseline (p<0.001) for both sites. Although at baseline, Candida spp. counts were higher on the denture base (p<0.001), no significant differences were observed between the collected areas within the other time points (p<0.05). Also, 0.5% SH effectively reduced clinical signs of DS after treatment (p<0.05). Conclusion: The protocol tested effectively decreased Candida spp. levels on the denture base and palatal mucosa and effectively reduced the signs of DS

ENDOCRINOLOGIA PEDIÁTRICA: ATUALIZAÇÕES EM DISTÚRBIOS HORMONAIS NA INFÂNCIA

  Pediatric endocrinology is a vital area of medicine that requires constant updating and research. By studying hormonal disorders in childhood and pediatric endocrinology, we can hope to improve the quality of life and care of children affected by these disorders. The aim of this study was to look at the latest updates on hormonal disorders in childhood, with a focus on pediatric endocrinology. To this end, a systematic literature review was carried out, selecting scientific studies published between 2019 and 2024, available in the Scielo, Medline and Lilacs databases. After analyzing the results, the main conclusion is that recent advances in genetic research have provided a deeper understanding of the molecular basis of pediatric hormonal disorders, such as Kallmann syndrome and Prader-Willi syndrome, paving the way for more targeted and effective therapies in the future.  A endocrinologia pediátrica é uma área vital da medicina que requer constante atualização e pesquisa. Por meio do estudo dos distúrbios hormonais na infância e da endocrinologia pediátrica, é possível esperar a melhoria da qualidade de vida e o cuidado das crianças afetadas por esses distúrbios. Trata-se de um estudo cujo objetivo foi estudar atualizações mais recentes em distúrbios hormonais na infância, com foco na endocrinologia pediátrica. Nesse sentido, realizou-se uma revisão sistemática de literatura, com a seleção de estudos científicos publicados entre os anos de 2019 e 2024, disponíveis nas bases de dados Scielo, Medline e Lilacs. Após análise dos resultados, a principal conclusão é que avanços recentes na pesquisa genética têm proporcionado uma compreensão mais profunda das bases moleculares de distúrbios hormonais pediátricos, como a síndrome de Kallmann e a Síndrome de Prader-Willi, abrindo caminho para terapias mais direcionadas e eficazes no futuro

MANEJO DE CRISES DE ANSIEDADE E PÂNICO EM CRIANÇAS E ADOLESCENTES: CONDIÇÕES MULTIFATORIAIS

The objective of this article is to explore the nuances and strategies in managing anxiety and panic attacks in children and adolescents, recognizing the multifactorial conditions involved. It seeks to offer insights and practical guidance for healthcare professionals, parents and educators in addressing these complexities in the pediatric context. Methodology: Several academic platforms were explored, such as PubMed, Scopus, Web of Science and Scielo, during the research. The key terms "anxiety crisis", "panic syndrome", "children" and "adolescents" were used. The PICO (Population; Intervention; Comparison; Outcome) approach was used to improve the search, delimiting the target population, the interventions studied, comparisons when relevant and the outcomes of interest. Results: The study highlights the need for personalized approaches in the management of anxiety and panic attacks in children and adolescents, considering the diversity of factors involved. Interventions adapted to individual peculiarities and an in-depth understanding of multifactorial conditions are essential to promote a positive impact on the emotional well-being of these young people. Conclusion: A sensitive and ethical approach to the diagnosis and treatment of panic syndrome in children and adolescents, considering cultural factors, is essential to promote effective and patient-centered interventions, ensuring well-being and respecting individual complexities.O objetivo deste artigo é explorar as nuances e estratégias no manejo de crises de ansiedade e pânico em crianças e adolescentes, reconhecendo as condições multifatoriais envolvidas. Busca-se oferecer insights e orientações práticas para profissionais de saúde, pais e educadores na abordagem dessas complexidades no contexto pediátrico. Metodologia:  Foram exploradas várias plataformas acadêmicas, como PubMed, Scopus, Web of Science e Scielo, durante a pesquisa. Os termos-chave "crise de ansiedade", "síndrome do pânico", "crianças" e "adolescentes" foram utilizados. A abordagem PICO (População; Intervenção; Comparação; Outcome) foi empregada para aprimorar a busca, delimitando a população-alvo, as intervenções estudadas, comparações quando relevantes e os desfechos de interesse. Resultados: O estudo destaca a necessidade de abordagens personalizadas no manejo de crises de ansiedade e pânico em crianças e adolescentes, considerando a diversidade de fatores envolvidos. Intervenções adaptadas às peculiaridades individuais e uma compreensão aprofundada das condições multifatoriais são fundamentais para promover um impacto positivo no bem-estar emocional desses jovens. Conclusão: A abordagem sensível e ética no diagnóstico e tratamento da síndrome do pânico em crianças e adolescentes, considerando fatores culturais, é essencial para promover intervenções eficazes e centradas no paciente, garantindo o bem-estar e respeitando as complexidades individuais

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Transtorno bipolar em crianças: análise de relato de caso 2018-2023

O transtorno bipolar em crianças é uma realidade clínica que demanda atenção especializada. A compreensão dos sintomas, fatores de risco, prevalência e desafios diagnósticos é fundamental para proporcionar intervenções precoces e adequadas, visando melhorar a qualidade de vida desses jovens e reduzir o impacto a longo prazo dessa condição psiquiátrica. Trata-se de um estudo cujo objetivo foi objetivo revisar relatos de caso publicados entre 2018 e 2023 sobre transtorno bipolar em crianças, identificando o estado da arte desses estudos. Para isso, se realizou uma revisão sistemática de literatura utilizando as bases de dados Medical Literature Analysis and Retrieval System Online (MEDLINE), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Scientific Electronic Library Online (SCIELO). Com a análise e interpretação qualitativa dos resultados, a principal conclusão deste estudo é que o transtorno bipolar na infância é uma condição complexa, manifestando-se com comportamentos consistentes com o Transtorno de Conduta e sendo influenciado por fatores ambientais, familiares e genéticos. O tratamento eficaz requer uma abordagem multidisciplinar, integrando intervenções farmacológicas e não farmacológicas, personalizadas conforme as necessidades individuais. A supervisão familiar é crucial para a adesão ao tratamento, mas reconhece-se a necessidade contínua de pesquisa para aprimorar as estratégias terapêuticas diante da diversidade de casos

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages