Femoral Nerve Injury as a Complication of Percutaneous Simple Renal Cyst Sclerotherapy with Ethanol: A Case Report

Simple renal cysts are benign, common, and often asymptomatic disease in old age, sometimes treated with ethanol sclerotherapy. We report a case of iatrogenic femoral nerve injury following percutaneous injection of ethanol into a renal cyst under sedation. The percutaneous injection was guided by sonography. At the end of the procedure, the cyst ruptured so the patient progressed to loss of consciousness due to alcohol intoxication. Ethanol was damaged to the femoral nerve, so patient was developed with limping, numbness, and weakness in anteromedial aspect of the right thigh. To the best of our knowledge, this is the first report of femoral nerve injury caused by percutaneous simple renal cyst sclerotherapy with ethanol. This rare event has not been previously described, Physicians should be aware of the possibility of this complication

Excisional wound healing activity of Carboxymethyle cellulose in diabetic rat

Introduction:Wound healing is a complex process that occurs after injury and as a result of the cellular and biochemical interactions between various components in the wound area. Many new methods have been used to treat diabetic ulcers. In recent decades, a dramatic increase in the number and types of treatment for diabetic ulcers has been observed. Despite a new approach to the basic cellular and molecular therapy, diabetic wound healing remains one of the clinical problems.Material and Methods:In this experimental study, excisional wound healing activity of Carboxymethyle cellulose (CMC) was evaluated in 21 streptozotocin-induced diabetic Sprague dawley male rats that were randomly divided into three groups of seven rats (Group A, B and C with 4, 7 and 12 days of follow up, respectively). The animals were housed in standard environmental conditions with light/dark, temperature of 23 ± 20C, humidity of 50 ± 5%, and a 12h cycle. Healing process was evaluated using macroscopic (area mesurment) and histopathologic study.Results:The average area of wounds treated with CMC compared to the control wound was reduced with a statistically significant difference. The histopathologic study showed higher and lower inflammation on days 4 and 12, respectively. A lower level of tissue necrosis and hemorrhage and higher level of epithelialization were shown in wounds which were treated with CMC.Conclusion:Given the positive effects of CMC on wound healing of diabetic male rats, there is a need to conduct clinical trials on using this new Gel on diabetic and burn ulcers