40 research outputs found
Ankle-brachial index: A surrogate marker of coronary artery disease – An institutional based study
Get PDF3-Hydroxy-N-Methylpyrrolidone and Use as Transdermal Enhancer
Get PDFThe novel compound, 3-hydroxy-N-methylpyrrolidone, is effective as a transdermal enhancer for the absorption of drugs through the skin of humans and animals. The 3-hydroxy-N-methylpyrrolidone is prepared from delta-butyrolactone which is converted to methyl 2,4-dibromobutyrate, this intermediate is reacted with methylamine to form N-methyl-2,4-dibromobutyramide, this intermediate is converted to 3-bromo-N-methyl-2-pyrrolidone by ring closure, and the 3-bromo-N-methyl-2-pyrrolidone is reacted with an alkaline earth metal carbonate or alkaline metal carbonate to form 3-hydroxy-N-methyl-2-pyrrolidone
3-Hydroxy-N-Methylpyrrolidone and Preparation Thereof
Get PDFThe novel compound, 3-hydroxy-N-methylpyrrolidone, is effective as a transdermal enhancer for the absorption of drugs through the skin of humans and animals. The 3-hydroxy-N-methylpyrrolidone is prepared from delta-butyrolactone which is converted to methyl 2,4-dibromobutyrate, this intermediate is reacted with methylamine to form N-methyl-2,4-dibromobutyramide, this intermediate is converted to 3-bromo-N-methyl-2-pyrrolidone by ring closure, and the 3-bromo-N-methyl-2-pyrrolidone is reacted with an alkaline earth metal carbonate or alkaline metal carbonate to form 3-hydroxy-N-methyl-2-pyrrolidone
Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus
Get PDFPrevalence of coronary artery disease in patients with rheumatic and non-rheumatic valvular heart disease treated at Asian heart hospital, Mumbai
Get PDFIncidence of left coronary vessel dominance in patients of acute coronary syndrome: An institutional based coronary arteriographic study
Get PDFVentricular tachycardia in viral myocarditis managed by catheter ablation: A rare case report
Get PDFUse of dabigatran versus warfarin in patients of atrial fibrillation at Asian heart hospital – An institutional based study
Get PDFFibrolipoma: A rare entity - Case series
No full textLipomas are benign soft tissue neoplasms of mature adipose tissue usually seen in the head and neck region. Intraoral lipomas are rare lesions, which may be discovered during routine dental examinations since they present as a slow-growing, painless, and asymptomatic yellowish mass. Fibrolipoma is one of the rare variants of the lipoma, and very few cases have been reported in the oral cavity. These lesions infrequently cause pain, but may grow to large size causing difficulty in speech and mastication. Surgical excision is the treatment of choice, and the prognosis is generally good as recurrence rate is very less. Here, we present two cases of fibrolipoma and a brief review of literature
