Cardiac Cell Regeneration in Zebrafish A Systematic Review Study.

Objective: This research aims to increase the level and quality of the information acquired from 90 previously conducted studies regarding zebrafish heart regeneration and to summarize the best and latest information as well as the methods gleaned from those studies, which will allow us to determine the best ways to rebuild cardiac tissue in zebrafish. Methods: This study was conducted under the PRISMA guidelines. The search for primary research articles was conducted using PubMed, Web of science, and Mendeley. We used the latest update of Microsoft office Excel, Of the total 1158 results, 1066 were dropped according to the criteria for exclusion. The selected results included previously published and unpublished studies on cardiac cell regeneration in zebrafish from 2012 to 2022. Results: 90 studies met the inclusion criteria. Out of these, 43 used the AR method, 36 used cryoinjury, and 16 used genetic amputation. All methods used were based on selected heart sections, not the whole heart. The primary evaluation technique used in the included studies was histology, either alone or in combination with other methods. Acid Fuchsin Orange G (AFOG), Masson's Trichrome (MT), Hematoxylin/Eosin (HE), immunofluorescence (IF), and in situ hybridization (ISH) were the main histological techniques employed to assess heart regrowth and regeneration. Conclusion: This study may have a risk of bias due to the qualitative and quantitative data that was selected. Further research can help understand and utilize zebrafish regeneration genes in humans

Challenges and Opportunities in Community Nursing

Community health nursing is a comprehensive, holistic specialty. It is one of the ways through which the Health Department provides health care. Community health nursing not only focuses on the individual\u27s health needs, but the health of the collective population. By working with whole communities and the health care system, a community health nurse can greatly influence the health of a population. Community health nursing offers the nurse a unique opportunity to be involved with a changing area of health care. It is a rapidly evolving field. It is challenging, dynamic, and extremely rewarding. Because of changes in the health care system, shifts in disease patterns, a globalized world, and health disparities between populations, the role of the community nurse is more important than ever. As with any area of nursing, there are and will continue to be many challenges in this field. However, these challenges come with many opportunities. In the proceeding paper we will explore numerous facets of community health nursing, in addition to the aforementioned challenges and opportunities. We will begin with the history of community health nursing and how it came to be. We will also look at the definition of community, and the evolving roles of the community nurse. Then we will explore the various theoretical concepts common to the practice, including the social determinants of health, health promotion, and the epidemiological approach. Finally, we will focus on certain global issues in community health nursing, and the role of the WHO in the community

The Impact Of Technology On Nursing Education And Practice

This paper is a general overview of current technologies and their uses in nursing practice and education. The complexity of the healthcare environment has increased dramatically over the past few decades, and as such, a greater understanding of technology is necessary in today\u27s nursing practice. Many areas of clinical practice are being impacted by the introduction of information technology (IT). Over the last decade, electronic health records (EHRs) have increasingly been used in nursing. The major goal of these records is to improve the safety, quality, and efficiency of patient care. By incorporating knowledge-based tools within the EHR, new forms of clinical documentation, and various other innovative applications, the quality of care rendered to patients can be greatly improved. Health care is in the midst of a technological explosion. The one element that nurses must not lose is the humanistic, caring essence of nursing

The role of talent management and its outcomes to achieve sustainable competitive advantage: a critical investigation in Saudi Arabian oil and gas organisations

This Research investigates the concept of talent management (TM) practices in oil and gas industry. In addition, this research investigates TM relationship with internal organisational factors including leadership, organisational culture, employer branding, rewards system. This Research investigates that effect TM implementation on TM outcomes, which includes employee attitudes (commitment, satisfaction, engagement and motivation) and How can TM achieve sustainable competitive advantage in oil and gas organisations. Despite the increasing number of TM adoptions in various organisations in recent years, this research found that TM practices are still in the early stages of development with a lack of effective framework which required further development. The literature review identified the gaps in TM literature; prompting the development of a framework for understanding the relationship between TM, its outcomes and internal factors, which are critical for the effective TM implementation Accordingly, TM framework was developed to address the key shortcomings of existing TM practices in the oil and gas organisations and to provide practical guidelines to academics and practitioners. This research is supported by two major theories including Resource-Based View (RBV) theory and SET (Social Exchange Theory). RBV is used for explaining how internal resources (talented human resources) could induce competitive advantage and improve organisational performance. SET is used for analysing the relationship between the employees and the organisation. This research adopted an interpretivist research philosophy along with the case study of the oil and gas organisations in Saudi Arabia. A two-stage empirical study employing sequential mixed methods of data collection and analysis was adopted in this research. A series of 26 semi-structured qualitative interviews from diverse managerial levels from various oil and gas organisations who have thorough knowledge and experience of TM practices was conducted. In addition, a quantitative “survey” with 417 “talented employees “in oil and gas organisations. This research will use statistical techniques for analysing the data. The data collected from the survey will be input into IBM SPSS Statistics for analysis, while the qualitative data will be analysed using Microsoft Excel using descriptive statistics. The analysis of both qualitative and quantitative data has identified that TM practises can result in effective talent outcomes including increased employee commitment, motivation, satisfaction and performance and efficiency, which would result to achieve sustainable competitive advantage. The relationship was identified between TM practices, talent outcomes (employee’s attitudes) and organisational outcomes. This research also reflected that it is important to identify the most important the influencing factors of TM in organisations, so that TM implementation is effectively and efficiently managed across the organisations. The main contribution to the knowledge and practical arena is the development of a TM framework for the oil and gas organisations, supported by practical guidelines for its effective implementation. This research has identified that effective implementation of TM practices can lead achieve sustainable competitive advantage. A key limitation of the research was identified as the nature and distribution of the sample population. The Researcher recommends that TM practises should be aligned with organisational strategy and must be continuously updated according to the changes in the internal and external environments (with respect to organisations) in order to improve sustainable competitive advantage. The Researcher recommends that future research should focus on evaluating the relationship between the TM and other internal and external organisational factors, which leads to the better understanding of issues pertaining to TM implementation in the oil and gas organisations

Detection and Determination of Phenolic Acids in Plasma, RBCs, Surface of RBCs, Low Density Lipoprotein, and Very Low Density Lipoprotein from Pig Blood

Cancer touches the lives of people indirectly and directly throughout the world. People seek out ways to prevent this disease. Today studies have found that phenolic acids possess disease risk reduction properties as well as antioxidant properties. They reduce the risk of contracting various degenerative diseases such as cancers and cardiovascular diseases in vitro and in vivo models (1). Caffeic acid, Dihydrocaffeic acid and protocatechuic acid are all phenolic acids. These acids are plant metabolites that are widely distributed in foods, especially coffee and grains. The antioxidant functions of phenolic acids, which contributed by the hydroxyl group(s) on the aromatic ring, is considered to play an important role in preventing a number of pathological conditions in humans. The ability for the phenolic acid to enter all the compartments in the pig’s blood was found to follow this observable pattern at 20μM: % Plasma 3, 4-Dihydroxybenzoic acid > Dihydrocaffeic acid > Caffeic acid. % Free polyphenol (PBS) Dihydrocaffeic acid > Caffeic acid > 3,4-Dihydroxybenzoic acid. % Inside RBCs Caffeic acid > 3,4-Dihydroxybenzoic acid = Dihydrocaffeic acid. % Bound to Surface RBCs Caffeic acid > Dihydrocaffeic acid > 3,4-Dihydroxybenzoic acid. Phenolic acids are more binding to High Density Lipoprotein (HDL) and Albumin than Low Density Lipoprotein (LDL) and Very Low Density Lipoprotein (VLDL)

Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion

The glycoprotein YKL-40 is synthesized both by cancer cells and by tumor-associated macrophages and plays a functional role in tumor progression. Consequently, high serum YKL-40 levels have been associated with a poor prognosis in patients with several cancer types. The aim of this study is to assess pleural effusion and serum concentrations of YKL-40 in patients with different types of pleural effusions and to evaluate the diagnostic performance of YKL-40 in detecting malignant pleural effusion. Patients and methods: A prospective cohort study was carried out of 88 consecutive patients presenting with pleural effusions. The patients were divided into four groups: 22 patients with transudative effusions, 24 patients with parapneumonic pleural effusion and 8 patients with tuberculous pleural effusion and 34 patients with malignant pleural effusions. Blood and pleural fluid YKL-40 levels were measured using enzyme-linked immunosorbent assay. Results: Both serum HE4 levels and pleural effusion YKL-40 levels were significantly higher in patients with malignant effusions than in patients with transudative or non-malignant exudative effusions. A pleural fluid YKL-40 cut-off value of 256 ng/mL was found to predict malignant pleural effusions with a diagnostic sensitivity of 85.3% and specificity of 90.7%. Conclusion: The current study reports a finding of increased serum and pleural fluid YKL-40 levels in patients with malignant pleural effusions compared to non-malignant effusions

Prevalence and psychological impact of Acne vulgaris among female secondary school students in Arar city, Saudi Arabia, in 2018

Background: Acne vulgaris is a common heath problem affecting adolescents with considerable impact on their quality of life. Objective: To determine the prevalence of Acne vulgaris and its psychological impact among female secondary school students. Methods: A cross-sectional study was conducted during the period from January to March 2018, among all female secondary school students in 3 randomly selected schools, in Arar city (Saudi Arabia). The participants were clinically examined by a dermatologist to identify acne cases. Dermatological quality of life of acne cases were assessed using an Arabic version of Dermatology Life Quality Index (DLQI). Data collected were analyzed by IBM-SPSS version 20, using Chi-square, Fisher’s Exact test, Mann-Whitney U, and Kruskal Wallis test. P- value ≤0.05 was considered statically significant. Results: The overall prevalence of Acne vulgaris was 14.3%. It was not significantly affected by age, marital status or nationality of participants. Post inflammatory hyper-pigmentation and scarring were detected in 11.6% and 8.7% respectively. Twenty nine percent of the cases had no impact; 56.3% had small to moderate impact and 14.5% had large effect. The psychological impact was significantly increased with increased severity, presence of acne lesions on face and other sites, presence of hyper pigmentation and scarring (p=0.001). Conclusion: Acne vulgaris had large impact on quality of life in 14.5% of cases. Students should be counseled and educated on how to deal with this dermatological problem

Perceptions of gender equality, work environment, support and social issues for women doctors at a university hospital in Riyadh, Kingdom of Saudi Arabia

<div><p>The Kingdom of Saudi Arabia (KSA) is an Islamic monarchy and was established in 1932. Saudi women first entered the medical field in 1975 and the country has since seen a steady increase in women pursuing medicine. However, there is limited data on gender related issues for women doctors practicing in Saudi Arabia. Therefore, our study objective was to assess the perception amongst peers regarding gender equality and social issues faced by women doctors in Saudi Arabia. An online anonymous cross-sectional survey was administered in English to doctors at King Khalid Hospital, affiliated to King Saud University, in Riyadh, between April and May of 2016. Of 1015 doctors, 304 (30%) participated, of which 129 (42.4%) were females and 231 (76%) were Saudi nationals. The average age was 32.4 years (±SD: 8.7). The majority opined that there was no gender discrimination in salaries (73.7% p-value = 0.4), hospital benefits (62.2% p-value = 0.06) or entry into any field of Medicine/Pediatrics (68.4% p-value = 0.207). However, only a minority believed that there was no gender discrimination for entry into surgery (37.3% p-value = .091). A higher proportion of male doctors agreed that promotion opportunities are equal (66.3% vs 45.7%, p-value = 0.002). However, of 54 consultants, only 18 (33.3%) were women. Over half of the women (52.3%) reported that they never wear the face veil. Only a minority of male and female doctors (12.2%) believed women doctors should wear the veil since they examine male patients. Fewer respondents believed that female doctors face harassment from male doctors (14.5%) whereas 30.7% believed female doctors face harassment from male patients. More females, than males, agreed with the statement that female doctors are as committed to their careers as are males (92.2% vs 67.4%, p-value<0.0001). Of 304 participants, 210 (69.1%) said that they would still choose to become a doctor with approximately equal proportions between males and females (68% vs 70.5%, p-value = 0.79). In conclusion, our survey of male and female doctors at a government university hospital in Saudi Arabia revealed that the majority believed there was gender equality amongst doctors in terms of salaries, benefits, opportunities for promotion and entry into any field of medicine or pediatrics, but not surgery. However, there were significantly fewer women at consultant positions, a deficiency that needs to be addressed.</p></div

Demographic characteristics of 304 doctors at King Khalid University Hospital, Riyadh.

<p>Demographic characteristics of 304 doctors at King Khalid University Hospital, Riyadh.</p

Hospital attire of women doctors at King Khalid University Hospital.

<p>Hospital attire of women doctors at King Khalid University Hospital.</p