Aprendendo com o Fred: Jogo didático e suas aplicações

Os recursos tecnológicos têm grande potencial de uso nas aulas em geral, sobretudo,no uso de alternativas didáticas para a realização de tais, fomentando assim ointeresse dos alunos e de professores. Dentre os recursos, destaca-se aqui o jogo didático,visto que este proporciona atração, afinidade, desejo e conhecimento por parte dos alunos.Defende-se aqui que o jogo, aliado à Geopolítica, contribui de maneira significativa paraa formação de cidadãos críticos. O presente artigo irá demonstrar o desenvolvimento dojogo “Aprendendo com o Fred”, que foi desenvolvido no período de aulas da disciplina deTecnologias Digitais de Informação e Comunicação na Educação: Formação de Professores,do curso de Mestrado em Educação, na Universidade Federal do Triângulo Mineiro

Economic analysis of an agrosilvipastoral system for a mountainous area in Zona da Mata Mineira, Brazil

O objetivo deste trabalho foi avaliar a viabilidade econômica de um sistema agrossilvipastoril, desenvolvido para áreas montanhosas da Zona da Mata mineira, Brasil, bem como comparar diferentes alternativas de comercialização da madeira (Eucalyptus grandis and Acacia mangium) do segundo desbaste. Os dados foram obtidos em um sistema agrossilvipastoril com dez anos de idade, implantado em área de quatro hectares, no Campo Experimental de Coronel Pacheco, pertencente à Embrapa Gado de Leite. Como critérios de avaliação para a análise de viabilidade econômica, foram utilizados os métodos do valor presente líquido e o da taxa interna de retorno, ambos calculados para a taxa de juros de 6%. Apesar da pouca diferença, a agregação de valor ao produto florestal aumentou a atratividade do sistema. Considerada isoladamente, a atividade agrícola se mostrou inviável, enquanto a silvicultura e a atividade pecuária foram independentemente viáveis. O sistema estudado parece ser igualmente tolerante a variações nos preços do produto florestal e do produto pecuário, assim como fortemente tolerante a variações nos custos de produção.The objective of this work was to evaluate the economic viability of an agrosilvipastoral system developed for Zona da Mata mountainous areas in Minas Gerais state, Brazil, as well as to compare different options for wood (Eucalyptus grandis and Acacia mangium) commercialization of the second thinning. The data were obtained from a 10 year-old agrosilvipastoral system established in four hectares at Embrapa Gado de Leite station in Coronel Pacheco, MG, Brazil. As evaluation criteria for the economic viability analysis, the adopted methods were the net present value (NPV) and the internal rate of return (IRR), both calculated at 6% interest rate. Despite the small difference, adding value to forest products increased the attractiveness of the proposed system. Considered separately, the agricultural activity was impracticable, whereas the forestry and livestock activities were independently viable. The studied system seems to be equally tolerant to price variations for forest and livestock products, as well as strongly tolerant to variations in production costs

Decepa de plantas jovens de eucalipto e manejo de brotações, em um sistema agroflorestal

This study aimed to evaluate juvenile eucalypt clone plant coppicing, in order to obtain small diameter logs, in the first rotation, which facilitates harvesting by small farmers; or to recover damaged young stands and to produce biomass for energy in short rotations. The experiment was carried out in an agroforestry system with 9.5x4 m spacing. Intact plant growth was compared to sprout growth from coppicing at nine and twelve months after planting. At six or nine months after coppicing, sprout thinning was carried out to leave two or three sprouts per stump. When thinning was done after 12 months of coppicing, all dominant sprouts were left. A treatment without thinning was also evaluated. Forty-two months after planting, treatment without thinning showed about the same amount of sprouts per stump as those thinned to three sprouts per stump. The estimated asymptotic value for sprout diameter was 69% of that for intact plants. The asymptotic value for sprout production, for most treatments of plants coppiced nine months after planting, was similar to that obtained for intact plants, which indicates that coppicing young eucalypt plants, without sprout thinning, can be used in agroforestry systems.O objetivo deste trabalho foi avaliar o uso de decepa de plantas jovens de eucalipto, para produção de árvores de menor diâmetro, com colheita facilitada por pequenos produtores; ou para recuperação de povoamentos jovens severamente danificados e produção de biomassa para energia em ciclos curtos. O experimento foi conduzido em sistema agroflorestal, com espaçamento entre plantas de 9,5x4 m. O crescimento de plantas intactas foi comparado ao de brotações de decepas realizadas aos nove ou doze meses após plantio. Aos seis ou nove meses após a decepa, realizou-se a desbrota, para deixar dois ou três brotos por cepa. Quando a desbrota foi realizada aos 12 meses após a decepa, todos os brotos dominantes foram deixados. Um tratamento sem desbrota também foi avaliado. Aos 42 meses após plantio, o tratamento sem desbrota apresentou o mesmo número de brotos por cepa que o de plantas desbrotadas para três brotos. O diâmetro das brotações foi equivalente a 69% do valor estimado para as plantas intactas. O valor assintótico de produção das brotações, da maioria dos tratamentos de decepa aos nove meses, foi igual ao das plantas intactas, o que evidencia a viabilidade da decepa sem a realização da desbrota, em sistemas agroflorestais

Bisphenol A increases hydrogen peroxide generation by thyrocytes both in vivo and in vitro

Bisphenol A (BPA) is the most common monomer in polycarbonate plastics and an endocrine disruptor. Though some effects of BPA on thyroid hormone (TH) synthesis and action have been described, the impact of this compound on thyroid H2O2 generation remains elusive. H2O2 is a reactive oxygen species (ROS), which could have deleterious effect on thyrocytes if in excess. Therefore, herein we aimed at evaluating the effect of BPA exposition both in vivo and in vitro on H2O2 generation in thyrocytes, besides other essential steps for TH synthesis. Female Wistar rats were treated with vehicle (control) or BPA 40 mg/kg BW for 15 days, by gavage. We then evaluated thyroid iodide uptake, mediated by sodium-iodide symporter (NIS), thyroperoxidase (TPO) and dual oxidase (DOUX) activities (H2O2 generation). Hydrogen peroxide generation was increased, while iodide uptake and TPO activity were reduced by BPA exposition. We have also incubated the rat thyroid cell line PCCL3 with 10−9 M BPA and evaluated Nis and Duox mRNA levels, besides H2O2 generation. Similar to that found in vivo, BPA treatment also led to increased H2O2 generation in PCCL3. Nis mRNA levels were reduced and Duox2 mRNA levels were increased in BPA-exposed cells. To evaluate the importance of oxidative stress on BPA-induced Nis reduction, PCCL3 was treated with BPA in association to N-acetylcysteine, an antioxidant, which reversed the effect of BPA on Nis. Our data suggest that BPA increases ROS production in thyrocytes, what could lead to oxidative damage thus possibly predisposing to thyroid disease

A hybrid deep learning forecasting model using GPU disaggregated function evaluations applied for household electricity demand forecasting.

As the new generation of smart sensors is evolving towards high sampling acquisitions systems, the amount of information to be handled by learning algorithms has been increasing. The Graphics Processing Unit (GPU) architectures provide a greener alternative with low energy consumption for mining big-data, harnessing the power of thousands of processing cores in a single chip, opening a widely range of possible applications. Here, we design a novel evolutionary computing GPU parallel function evaluation mechanism, in which different parts of time series are evaluated by different processing threads. By applying a metaheuristics fuzzy model in a low-frequency data for household electricity demand forecasting, results suggested that the proposed GPU learning strategy is scalable as the number of training rounds increases

Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in Portugal

Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the highest impact on case numbers and fitted them into a global context, finding evidence that several international sublineages probably emerged or spread early in Portugal. We estimated a 62% infection reporting rate and that 1.3% of the population of men who have sex with men in Portugal were infected. We infer the critical role played by sexual networks and superspreader gatherings, such as sauna attendance, in the dissemination of mpox virus. Overall, our findings highlight genomic epidemiology as a tool for the real-time monitoring and control of mpox epidemics, and can guide future vaccine policy in a highly susceptible population.info:eu-repo/semantics/publishedVersio