A Demo of a Dynamic Facial UI for Digital Artists

Part 1: Long and Short PapersInternational audienceCharacter facial animation is difficult because the face of a character assumes many complex expressions. To achieve convincing visual results for animation, 3D digital artists need to prepare their characters with sophisticated control structures. One of the most important techniques to achieve good facial animation is to use facial control interfaces, also called facial user interfaces, or facial UI’s. But facial UI’s are usually dull and often confusing, with limited user interaction and no flexibility. We developed a concept and a working prototype of a dynamic facial UI inside the Blender [1] open-source software to allow their large community of digital artists to better control and organize the facial animation of a character. Our interactive system is running stable in the latest version of Blender and we started to build a full-face dynamic UI to show its interactive potential in a character’s face

Biases in face representation.

<p>A Schematic of feature locations used to instruct participants. B. Actual and mean represented locations. C, Average of 50 female faces reproduced with permission from <a href="http://www.perceptionlab.com" target="_blank">www.perceptionlab.com</a>. Blue arrows indicate mean judgement error for each feature. D. Average female face adjusted according to the mean represented locations of our participants. E, F: as for C, D with average of 50 male faces.</p

Synthesis and Biological Evaluation of 1α,25-Dihydroxyvitamin D₃ Analogues with a Long Side Chain at C12 and Short C17 Side Chains

Structure-guided optimization was used to design new analogues of 1α,25-dihydroxyvitamin D₃ bearing the main side chain at C12 and a shorter second hydroxylated chain at C17. The new compounds <b>5a</b>–<b>c</b> were efficiently synthesized from ketone <b>9</b> (which is readily accessible from the Inhoffen–Lythgoe diol) with overall yields of 15%, 6%, and 3% for <b>5a</b>, <b>5b</b>, and <b>5c</b>, respectively. The triene system was introduced by the Pd-catalyzed tandem cyclization–Suzuki coupling method. The new analogues were assayed against human colon and breast cancer cell lines and in mice. All new vitamin D₃ analogues bound less strongly to the VDR than 1α,25-dihydroxyvitamin D₃ but had similar antiproliferative, pro-differentiating, and transcriptional activity as the native hormone. In vivo, the three analogues had markedly low calcemic effects