PHOTOGRAMMETRIC WIREFRAME AND DENSE POINT CLOUD 3D MODELLING OF HISTORICAL STRUCTURES: THE STUDY OF SULTAN SELIM MOSQUE AND YUSUF AGA LIBRARY IN KONYA, TURKEY

The photogrammetry enables to getting high accuracy measurement with low-cost and easy application in documentation of historical structures. The object details are signified with lines in cultural heritage documentation by photogrammetry. The combination of all the lines create 3D wireframe model of the measurement object. In addition, patch surfaces of the wireframe are mapped with the texture from the images for more realistic visualization. On the other hand, the progress on computer vision and image processing techniques is allowing automatically perform the photogrammetric process. A large number of points that are called dense point cloud can be measured from coverage area of multi view images. The dense point cloud represents the object shape with small space measured points while the wireframe photogrammetry is representing the object with lines. In this study these two photogrammetric methods were evaluated with respect to visualization, cost, labour and measurement time through 3D modelling of historical structures of Sultan Selim Mosque and Yusuf Aga Library

Impaired cytokine expression, neutrophil infiltration and bacterial clearance in response to urinary tract infection in diabetic mice

Diabetic patients have increased susceptibility to infections, and urinary tract infections ( UTI) are the most common type in women with diabetes mellitus. Knowledge of bacterial clearance effectiveness following UTI in diabetics is sparse. In this study, the effects of diabetes on bacterial clearance efficiency and components of the innate immune system in response to UTI in a murine model were investigated. Streptozotocin-induced diabetic and control female C57BL/6J mice were infected with uropathogenic Escherichia coli, and bacterial load, expression of chemokines, and neutrophil infiltration in the bladder over time were investigated. Expression levels of histone deacetylases were also measured to address a potential mechanism underlying the phenotype. Bacterial clearance during UTI was significantly prolonged in diabetic mice relative to controls. Neutrophil infiltration in bladder tissue and urine, and both mRNA and protein expression of chemokines MIP-2, KC, MCP-1 and IL-6 in bladder tissue were diminished at early time points after infection in diabetic mice relative to controls. In addition, mRNA levels of histone deacetylases 1-5 were increased in diabetic mice. This is the first study to show an association of impaired bacterial clearance in diabetic mice with suppression of UTI-induced chemokine expression and neutrophil infiltration in the bladder