Systematic Review in Patients with Benign Prostatic Hyperplasia for The Role of Prostatic Arterial Embolization

This study aimed at reviewing the role of Prostatic Arterial Embolization (PAE) as a new treatment producer for patients with Benign Prostatic Hyperplasia (BPH). The study reviewed the recent researches of  Prostatic Arterial Embolization (PAE) as a new treatment technique and concluded that the initial reported results of PAE seem promising, mainly during the first 12 months after treatment. However, no comparison was made to medical therapy or surgical therapies. Overlapping patient data and reporting bias could not be excluded. None of the included studies performed a power analysis. Also, a relatively small number of patients are treated with a short follow-up period. Therefore, more studies are needed with more patients and longer periods of follow-up, compared with standard medical and surgical therapies, to assess whether PAE is an effective and safe alternative treatment for BPH

A Systemic Review of Iron Deficiency Anemia in Adults and the Clinical Management of Diagnosis and Treatment

Iron deficiency is the most frequent cause of anaemia worldwide. It impairs quality of life, increases asthenia and can lead to clinical worsening of patients. In addition, iron deficiency has a complex mechanism whose pathologic pathway is recently becoming better understood. The discovery of hepcidin has allowed a better clarification of iron metabolism regulation. Furthermore, the ratio of concentration of soluble transferrin receptor to the log of the ferritin level, has been developed as a tool to detect iron deficiency in most situations. Therefore, the problem of this research lies in exploring the cause of iron deficiency that always be sought because the underlying condition can be serious. This review will summarize the current knowledge regarding diagnostic algorithms for iron deficiency anemia. The majority of aetiologies occur in the digestive tract, and justify morphological examination of the gut. First line investigations are upper gastrointestinal endoscopy and colonoscopy, and when negative, the small bowel should be explored; newer tools such as video capsule endoscopy have also been developed. The treatment of iron deficiency is aetiological if possible and iron supplementation whether in oral or in parenteral form