430 research outputs found
Chromosomal rearrangement segregating with adrenoleukodystrophy: associated changes in color vision.
LNCS
We introduce the monitoring of trace properties under assumptions. An assumption limits the space of possible traces that the monitor may encounter. An assumption may result from knowledge about the system that is being monitored, about the environment, or about another, connected monitor. We define monitorability under assumptions and study its theoretical properties. In particular, we show that for every assumption A, the boolean combinations of properties that are safe or co-safe relative to A are monitorable under A. We give several examples and constructions on how an assumption can make a non-monitorable property monitorable, and how an assumption can make a monitorable property monitorable with fewer resources, such as integer registers
Unemployment Through Learning from Experience
Digitised version produced by the EUI Library and made available online in 2020
Almost optimal asynchronous rendezvous in infinite multidimensional grids
Two anonymous mobile agents (robots) moving in an asynchronous manner have to meet in an infinite grid of dimension δ> 0, starting from two arbitrary positions at distance at most d. Since the problem is clearly infeasible in such general setting, we assume that the grid is embedded in a δ-dimensional Euclidean space and that each agent knows the Cartesian coordinates of its own initial position (but not the one of the other agent). We design an algorithm permitting the agents to meet after traversing a trajectory of length O(d δ polylog d). This bound for the case of 2d-grids subsumes the main result of [12]. The algorithm is almost optimal, since the Ω(d δ) lower bound is straightforward. Further, we apply our rendezvous method to the following network design problem. The ports of the δ-dimensional grid have to be set such that two anonymous agents starting at distance at most d from each other will always meet, moving in an asynchronous manner, after traversing a O(d δ polylog d) length trajectory. We can also apply our method to a version of the geometric rendezvous problem. Two anonymous agents move asynchronously in the δ-dimensional Euclidean space. The agents have the radii of visibility of r1 and r2, respectively. Each agent knows only its own initial position and its own radius of visibility. The agents meet when one agent is visible to the other one. We propose an algorithm designing the trajectory of each agent, so that they always meet after traveling a total distance of O( ( d)), where r = min(r1, r2) and for r ≥ 1. r)δpolylog ( d r
Gathering in Dynamic Rings
The gathering problem requires a set of mobile agents, arbitrarily positioned
at different nodes of a network to group within finite time at the same
location, not fixed in advanced.
The extensive existing literature on this problem shares the same fundamental
assumption: the topological structure does not change during the rendezvous or
the gathering; this is true also for those investigations that consider faulty
nodes. In other words, they only consider static graphs. In this paper we start
the investigation of gathering in dynamic graphs, that is networks where the
topology changes continuously and at unpredictable locations.
We study the feasibility of gathering mobile agents, identical and without
explicit communication capabilities, in a dynamic ring of anonymous nodes; the
class of dynamics we consider is the classic 1-interval-connectivity.
We focus on the impact that factors such as chirality (i.e., a common sense
of orientation) and cross detection (i.e., the ability to detect, when
traversing an edge, whether some agent is traversing it in the other
direction), have on the solvability of the problem. We provide a complete
characterization of the classes of initial configurations from which the
gathering problem is solvable in presence and in absence of cross detection and
of chirality. The feasibility results of the characterization are all
constructive: we provide distributed algorithms that allow the agents to
gather. In particular, the protocols for gathering with cross detection are
time optimal. We also show that cross detection is a powerful computational
element.
We prove that, without chirality, knowledge of the ring size is strictly more
powerful than knowledge of the number of agents; on the other hand, with
chirality, knowledge of n can be substituted by knowledge of k, yielding the
same classes of feasible initial configurations
Hidden spin-texture at topological domain walls drive exchange bias in a Weyl semimetal
Exchange bias is a phenomenon critical to solid-state technologies that
require spin valves or non-volatile magnetic memory. The phenomenon is usually
studied in the context of magnetic interfaces between antiferromagnets and
ferromagnets, where the exchange field of the former acts as a means to pin the
polarization of the latter. In the present study, we report an unusual instance
of this phenomenon in the topological Weyl semimetal Co3Sn2S2, where the
magnetic interfaces associated with domain walls suffice to bias the entire
ferromagnetic bulk. Remarkably, our data suggests the presence of a hidden
order parameter whose behavior can be independently tuned by applied magnetic
fields. For micron-size samples, the domain walls are absent, and the exchange
bias vanishes, suggesting the boundaries are a source of pinned uncompensated
moment arising from the hidden order. The novelty of this mechanism suggests
exciting opportunities lie ahead for the application of topological materials
in spintronic technologies.Comment: Main text: 11 pages, 4 figures. Supplementary information: 7 pages, 6
figures. Supplementary videos:
eLife
The functions of the TAF subunits of mammalian TFIID in physiological processes remain poorly characterised. In this study, we describe a novel function of TAFs in directing genomic occupancy of a transcriptional activator. Using liver-specific inactivation in mice, we show that the TAF4 subunit of TFIID is required for post-natal hepatocyte maturation. TAF4 promotes pre-initiation complex (PIC) formation at post-natal expressed liver function genes and down-regulates a subset of embryonic expressed genes by increased RNA polymerase II pausing. The TAF4-TAF12 heterodimer interacts directly with HNF4A and in vivo TAF4 is necessary to maintain HNF4A-directed embryonic gene expression at post-natal stages and promotes HNF4A occupancy of functional cis-regulatory elements adjacent to the transcription start sites of post-natal expressed genes. Stable HNF4A occupancy of these regulatory elements requires TAF4-dependent PIC formation highlighting that these are mutually dependent events. Local promoter-proximal HNF4A-TFIID interactions therefore act as instructive signals for post-natal hepatocyte differentiation
Towards Logical Specification of Statistical Machine Learning
We introduce a logical approach to formalizing statistical properties of
machine learning. Specifically, we propose a formal model for statistical
classification based on a Kripke model, and formalize various notions of
classification performance, robustness, and fairness of classifiers by using
epistemic logic. Then we show some relationships among properties of
classifiers and those between classification performance and robustness, which
suggests robustness-related properties that have not been formalized in the
literature as far as we know. To formalize fairness properties, we define a
notion of counterfactual knowledge and show techniques to formalize conditional
indistinguishability by using counterfactual epistemic operators. As far as we
know, this is the first work that uses logical formulas to express statistical
properties of machine learning, and that provides epistemic (resp.
counterfactually epistemic) views on robustness (resp. fairness) of
classifiers.Comment: SEFM'19 conference paper (full version with errors corrected
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