Sistema interactivo de tutorización, información y preguntas frecuentes (FAQS) para asignaturas adaptadas al EEES

Memoria ID-116. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2010-2011.El presente proyecto ha creado una nueva herramienta de comunicación con los estudiantes para los alumnos que prefieren consultar a su profesor y utilizar su tutoría aprovechando las nuevas tecnologías. También lo hemos utilizado para poner en marcha nuevas prácticas de asignaturas y para introducir a los estudiantes en pequeños trabajos y una introducción a la investigación. El resultados principal ha sido mejorar los resultados en las asignaturas adaptadas al Espacio Europeo de Educación Superior y tener una vía complementaria para impulsar la comunicación entre el profesor y el estudiante

Álbum virtual de Histología vegetal. Uso de Instagram como herramienta para el aprendizaje

Memoria ID-0004. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2016-2017

Transient expression of calretinin in the trout habenulo-interpeduncular system during development

Calcium-binding proteins control calcium homeostasis during neural development. The expression of one of these proteins, calretinin (CR), was monitored by immunohistochemistry in the developing habenulo-interpeduncular system of the rainbow trout, a conserved region of the brain along vertebrate phylogeny that undergoes a neurochemical reorganization in late development. No CR-immunoreactivity was observed in the habenulo-interpeduncular system during the embryonic development. CRimmunolabeling appeared in newly hatched fry, and during the fry development the number of CR-immunostained elements increased progressively. During the juvenile stages (from 30 days post-hatching onwards) a gradual decrease in the number of CRimmunostained cells occurred, until its complete disappearance in adults. These variations in CR expression may represent variable calcium-buffering needs during different developmental stages

Gamificación educativa, control de asistencia y evaluación continua mediante Kahoot en clases teóricas y prácticas

Memoria ID-107. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2018-2019

Immunohistochemical distribution of secretagogin in the mouse brain

Introduction: Calcium is essential for the correct functioning of the central nervous system, and calcium-binding proteins help to finely regulate its concentration. Whereas some calcium-binding proteins such as calmodulin are ubiquitous and are present in many cell types, others such as calbindin, calretinin, and parvalbumin are expressed in specific neuronal populations. Secretagogin belongs to this latter group and its distribution throughout the brain is only partially known. In the present work, the distribution of secretagogin-immunopositive cells was studied in the entire brain of healthy adult mice. Methods: Adult male C57BL/DBA mice aged between 5 and 7 months were used. Their whole brain was sectioned and used for immunohistochemistry. Specific neural populations were observed in different zones and nuclei identified according to Paxinos mouse brain atlas. Results: Labelled cells were found with a Golgi-like staining, allowing an excellent characterization of their dendritic and axonal arborizations. Many secretagogin-positive cells were observed along different encephalic regions, especially in the olfactory bulb, basal ganglia, and hypothalamus. Immunostained populations were very heterogenous in both size and distribution, as some nuclei presented labelling in their entire extension, but in others, only scattered cells were present. Discussion: Secretagogin can provide a more complete vision of calcium-buffering mechanisms in the brain, and can be a useful neuronal marker in different brain areas for specific populations.This work was supported by the Ministry of Economy, Industry and Competitiveness (MINECO) (SAF2016-79668- R to EW), the Ministry of Science and Innovation (PID2019- 106943RB-I00 to EW), the Ministry of Universities (MIU) (FPU20/03457 to PT), the Regional Government of Castile and Leon (SA178U13 to EW; EDU/556/2019 to LP-R), the Centre for Regenerative Medicine and Cell Therapy of Castile and Leon (EW), and the University of Salamanca (EW)

Sacar las clases prácticas del laboratorio a la calle: Foldscope. Uso de microscopios plegables como herramienta docente

Memoria ID-112. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2019-2020.[ES]El objetivo general es introducir un innovadora herramienta docente de imagen que supere la dificultad de contar con la herramienta básica, el microscopio, en las asignaturas que estudian las células y tejidos. Incluye que los alumnos se conviertan en el sujeto central del proceso educativo y exploren la organización de animales, plantas, hongos y organismos unicelulares en su entorno (comida, naturaleza, aguas contaminadas, etc.

Museo virtual de la neurociencia

Memoria ID-0154. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2015-2016

Multiple vertebral fractures after suspension of denosumab. A series of 56 cases

Background: Denosumab is a monoclonal antibody approved for the treatment of postmenopausal osteoporosis. The withdrawal of denosumab produces an abrupt loss of bone mineral density and may cause multiple vertebral fractures (MVF). Objective: The objective of this study is to study the clinical, biochemical, and densitometric characteristics in a large series of postmenopausal women who suffered MVF after denosumab withdrawal. Likewise, we try to identify those factors related to the presence of a greater number of vertebral fractures (VF). Patients and methods: Fifty-six patients (54 women) who suffered MVF after receiving denosumab at least for three consecutive years and abruptly suspended it. A clinical examination was carried out. Biochemical bone remodelling markers (BBRM) and bone densitometry at the lumbar spine and proximal femur were measured. VF were diagnosed by magnetic resonance imaging MRI, X-ray, or both at dorsal and lumbar spine. Results: Fifty-six patients presented a total of 192 VF. 41 patients (73.2%) had not previously suffered VF. After discontinuation of the drug, a statistically significant increase in the BBRM was observed. In the multivariate analysis, only the time that denosumab was previously received was associated with the presence of a greater number of VF (P = .04). Conclusions: We present the series with the largest number of patients collected to date. 56 patients accumulated 192 new VF. After the suspension of denosumab and the production of MVF, there was an increase in the serum values of the BBRM. The time of denosumab use was the only parameter associated with a greater number of fractures

Talleres de olfacción y gusto: prácticas académicas y divulgativas de sistemas sensoriales químicos

Memoria ID-185. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2013-2014