Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report

Cor triatriatum is a rare congenital cardiac malformation and it usually refers to the left atrium. We report an unusual case of cor triatriatum in a 33 - year old woman presented with congestive heart failure caused by left ventricular systolic dysfunction

The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer - a multicentre observational study

Objective To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper tract urothelial cancer [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers and geographical variation. Patients and Methods This was an international multicentre prospective observational study. We included patients aged ≥16 years, referred to secondary care with suspected urinary tract cancer. Patients with a known or previous urological malignancy were excluded. We estimated the prevalence of bladder cancer, UTUC, renal cancer and prostate cancer; stratified by age, type of haematuria, sex, and smoking. We used a multivariable mixed-effects logistic regression to adjust cancer prevalence for age, type of haematuria, sex, smoking, hospitals, and countries. Results Of the 11 059 patients assessed for eligibility, 10 896 were included from 110 hospitals across 26 countries. The overall adjusted cancer prevalence (n = 2257) was 28.2% (95% confidence interval [CI] 22.3–34.1), bladder cancer (n = 1951) 24.7% (95% CI 19.1–30.2), UTUC (n = 128) 1.14% (95% CI 0.77–1.52), renal cancer (n = 107) 1.05% (95% CI 0.80–1.29), and prostate cancer (n = 124) 1.75% (95% CI 1.32–2.18). The odds ratios for patient risk markers in the model for all cancers were: age 1.04 (95% CI 1.03–1.05; P < 0.001), visible haematuria 3.47 (95% CI 2.90–4.15; P < 0.001), male sex 1.30 (95% CI 1.14–1.50; P < 0.001), and smoking 2.70 (95% CI 2.30–3.18; P < 0.001). Conclusions A better understanding of cancer prevalence across an international population is required to inform clinical guidelines. We are the first to report urinary tract cancer prevalence across an international population in patients referred to secondary care, adjusted for patient risk markers and geographical variation. Bladder cancer was the most prevalent disease. Visible haematuria was the strongest predictor for urinary tract cancer

Reversion of resistance in relapsing infection caused by a glycopeptide-intermediate methicillin-resistant Staphylococcus aureus isolate.

Case ReportsJournal Articleinfo:eu-repo/semantics/publishe

Evaluation of transboundary pollution levels in the Axios river (Greece, former Yugoslavian republic of Macedonia) - Direct and indirect impacts on man and environment

The present paper is a part of a greater research project aiming to determine the transboundary pollution of the Axios river, its water quality and the direct and indirect impacts to human health and environment. In the framework of this project, it has been determined the physicochemical and microbiological quality parameters, the presence of toxic chemical compounds and elements such as metals, pesticides and other related organic pollutants in various sampling stations. The analyses of the Axios river water showed the presence of one or more pesticides in all sampling stations, but in concentrations lower than 0.1 mu g/l, which is the highest permitted limit for each pesticide in drinking water, according to the Directive 778/80 of the European Union. The polychlorinated biphenyls show relatively high total concentrations in all sampling stations in the Greek part of the Axios river sediment. The levels of some heavy metals in river water and sediment are relatively high both in the Greek part and the FYR of Macedonia part of the Axios river. The results showed a significant degradation of the water quality of the Axios river, which is mainly due to the presence of toxic organic pollutants like pesticides, PCBs and heavy metals and it can be assumed that there is an environmental risk, possibly because of irrigation with water from the river