What We Know About the Genetic Determinants of Human Homosexuality? A Short Review Communication

“Homosexualism”, “sexual orientation disorder”, “egodistonic homosexuality”, “unspecified sexual disorder”, “sexual maturity disorder” and “sexual relationship disorder”. Since 1948, these have been, throughout the history of the Diagnostic and Statistical Manual of Mental Disorders (DCM) and the International Statistical Classification of Diseases and Related Health Problems (ICD), the terms used by the scientific community to categorize the homoaffective spectrum until in 2017, in the face of strong social and academic demand, their complete disengagement from any terminology that categorizes them as physical and/or mental illness. On the other hand, some areas of science have contributed substantially to a better understanding of this subject, such as genetics and epigenetics. Today, although the scientific community still offers some points of resistance, especially in more conservative countries, it is a consensus that since the implementation of the genome project there has been a considerable methodological expansion that has opened new possibilities of studies that have allowed this advance

Political, Historical and Social Features of the Human Right to Health: A Brief Interdisciplinary Review of the Literature

The consecration of the right to physical and mental integrity at the time of the establishment of the World Health Organization (WHO) in 1946 and the United Nations Universal Declaration of Human Rights (UN) in 1948 established the human right of access to health. Conversely, the practical guarantee of this right has gone through many nuances since then, so that today the process of its implementation is closely related to the political, historical and social aspects of each country, demanding from the administrative power an interdisciplinary look for this issue. The problem that involves this conjuncture drives the researchers of this field to question themselves: what is the role of the State in this right? What is the performance of health professionals in fact? Is it possible to achieve the universality of human rights in an economically and culturally globalized world? In the light of the above, this narrative review aimed to collect in the literature the scenarios that permeate this reality providing tacit examples of how the human right to health is shaped according to the conjunctures of insertion of each community that tries to implement i

Overview of University Actions Aimed at The Nutrition of Two Indigenous Communities In The Interior of The State of Mato Grosso Do Sul – Brazil: Report of Experience In Public Policies

The diet composed of adequate food is reported in the literature as one of the aspects of health promotion and maintenance, and it is the duty and obligation of the State to promote public policies that seek to meet these needs of the population. However, due to a number of factors, the minority or vulnerable populations end up not benefiting from a good part of the projects in force in Brazil. Thus, this work aimed to conduct a case study with two indigenous communities living in the interior of the State of Mato Grosso do Sul, listing the main points related to food practices, evaluation of the state of health in force and measures that help adherence to good food practices. The largest target audience was children from 0 (zero) to 12 (twelve) years, totaling 190 (one hundred and ninety), followed by newborns and puerperals who totaled 14 (fourteen) family nuclei and the elderly population of the community, which totaled 15 (fifteen). The service team was composed of Nutritionist, Health Agent, Social Worker and Nutrition Intern professionals. Several activities were developed, occurring according to the public attended during the different days of visit in the villages, mainly home visits, community actions such as vaccination campaigns, lectures and collective guidance. It is concluded that the measures adopted in public policies related to feeding the indigenous community is a powerful tool to provide the benefits for a better quality of life, well-being and maintenance of the health of indigenous peoples

Food Science from the Perspective of the Nutrition Professional

This work had as thematic the study in analysis of foods from the perspective of the nutrition professional. The objective of the research was to seek the training of this professional for the then analysis of the performance in quality control and formulation of products, with the perspective of assistance to projects carried out on site. This research was conducted in a community cafeteria located in a university in the interior of the State of Mato Grosso do Sul - Brazil. As a data collection tool, preparation technical sheets were used in which costs were collected, the preparation order, and the nutritional value provided. Sensory observation was used as an analysis of the data in order to measure and analyze and interpret the reactions of food and material characteristics. It appears that with the identification, attributions and activities developed by a nutritionist in the area, it became possible to analyze the processing of raw material and industrialized food products, according to the needs presented by the site. As for the points not reached were not due to any other factors than those related to the specificities of the research site, which did not prevent the acquisition of theoretical, practical, scientific, social and environmental knowledge of the points concerning the area of action of the nutritionist professional within the field of food science

Nutritional Health, Food Safety and its Social Determinants: A Brief Narrative Review

In its latest report, the United Nations for Food and Agriculture Organization (FAO) pointed out that the number of those who go hungry increased for the third year in a row affecting about 821 million people worldwide in 2018. Moreover, for the most part, studies show that food insecurity tends to follow social trends in such a way that it is precisely population groups in minorities or marginalized who are most likely to be exposed to food shortages and/or lack of access to adequate food. In this scenario, the concepts of food safety and insecurity gain prominence in the international debate playing a role of relevance to global public health. Achieving a healthy and sustainable food model is today one of the main objectives of modern and globalized society. With this, the main objective of this study is to collect in the scientific literature and discuss briefly about the social, environmental and geopolitical determinants that are (or should be) involved in the continuous process of effective human right to adequate feeding

Nutritional Intervention in the Area of Clinical Nutrition in a Hospital Environment: A Report of Field Experience

The present experience report narrates a nutritional intervention in the area of individual and collective clinical nutrition that took place in a University Hospital (HU) in the interior of the State of Mato Grosso do Sul - Brazil. The main objective of this field work was the professional training for hospital and outpatient nutritional care through general and specific activities performed on site. The specific activities consisted in writing care protocols and standardization of hospital diets while the general activities consisted in the analysis of medical records, survey of clinical diagnoses, proposal of dietotherapic conduct, monitoring of nutritional status, prescription and dietary adequacy, preparation of nutritional guidelines and development, presentation and discussion of clinical cases. This work also reports on the difficulties in implementing and carrying out this intervention agenda and, given the results obtained, it was concluded that the field experience in the hospital area was a valid and beneficial opportunity in which it was possible to harmonize theory with practice

Energy metabolism: gluconeogenesis and oxidative phosphorylation

Most animal cells are able to meet their energy needs from the oxidation of various types of compounds: sugars, fatty acids, amino acids, but some tissues and cells of our body depend exclusively on glucose and the brain is the largest consumer of all. That is why the body has mechanisms in order to keep glucose levels stable. As it decreases, the degradation of hepatic glycogen occurs, which maintains the appropriate levels of blood glucose allowing its capture continues by those tissues, even in times of absence of food intake. But this reserve is limited, so another metabolic pathway is triggered for glucose production, which occurs in the kidneys and liver and is called gluconeogenesis, which means the synthesis of glucose from non-glucose compounds such as amino acids, lactate, and glycerol. Most stages of glycolysis use the same enzymes as glycolysis, but it makes the opposite sense and differs in three stages or also called deviations: the first is the conversion of pyruvate to oxaloacetate and oxaloacetate to phosphoenolpyruvate. The second deviation is the conversion of fructose 1,6 biphosphate to fructose 6 phosphate and the third and last deviation is the conversion of glucose 6 phosphate to glucose

Anti-inflammatory foods: human food patterns, bioactive principles and mechanisms of action

With the increase in life expectancy accompanied by the gradual decrease in the birth rate as well as the greater income distribution associated with the quantitative increase in the minimum wage above inflation and the increase in its purchasing power, today the Brazilian population shows a moment exactly opposite to that found in the last century both in epidemiological terms and in the nutritional pattern. Brazil is currently experiencing the same pattern of mortality as developed countries: the majority of chronic non-communicable diseases are the main cause of death associated with an established model of obesity and sedentarism. These factors incline the scientific community and health professionals to turn their efforts to find food solutions that ease this epidemiological picture and it is in this context that anti-inflammatory foods have gained prominence. The following describes the main compounds that fit this magnitude of effect and their mechanisms of action

Nutritional physical examination: historical, methodological and applied approach

The historical interest in the use of physical evaluation skills in clinical settings gained new notoriety at the end of the 20th century with evidence that patients in intensive care units experienced increased morbidity and mortality related to poor nutritional status before and/or during their admission. This awareness of the adverse effects of malnutrition led to the need for screening and evaluation tools to identify nutritional risk. no clinical finding of EFN should be considered a diagnosis per se. It is academic, scientific and clinical consensus that its results should be interpreted as suggestive, being crucial to consider the other methods of clinical evaluation of the patient\u27s nutritional status for the correct global nutritional diagnosis. However, the systematic and periodic repetition of the test may help to follow the evolution of the individual\u27s nutritional status, especially in the long term. In summary, although it requires specialized training and continuous practice of the evaluator and/or the team – in addition to requiring complementary nutritional information – the physical nutritional examination can still be considered an effective adjuvant method in the clinical evaluation of the patient’s nutritional status

Endocannabinoid system: conceptual parameters, history and therapeutic possibilities

Among the drugs considered illicit in the West, the Cannabis sativa plant is the most consumed: around 4% of the adult population, 10% of these users are in a situation of dependence. However, the medicinal use of this herb dates back to the early days of the emergence of our own species: some anthropologists theorize that some of the genus Homo has progressed in the struggle for survival with other hominids precisely because of the advanced knowledge – kept to the proper proportions – it possessed of plants like Cannabis. Millennia later, science – even focusing intensely on the chemical characterization of its more than 530 bioactive components – was still not able to generate verifiable hypotheses in order to explain two of the most remarkable characteristics of the recreational use of this plant: because small chemical changes potentiated the effect of the drug up to 100 times and, mainly, because it would be virtually impossible for an individual to suffer a lethal overdose of the substance. To overcome this paradigm, some compounds derived from delta-ninetetrahydrocannabinol (Δ9-THC) - the main component of cannabis – were radioactively marked in an experimental study and, after their induction, it was discovered that they had tropism by brain membranes and that their binding was saturated and stereosleptic. Such evidence strongly suggested the existence of endogenous receptors for the drug and it was these findings that led to the discovery of the Endocanabinoid System (SEC): a physiological apparatus made up of endogenous receptors and binders, philogenetically conserved, responsible for several controls related to neuronal homeostasis