Representações sociais de Mulheres Surdas mirienses sobre si: da invisibilidade ao protagonismo

 Este artigo tem como objetivo analisar as representações sociais que as Mulheres Surdas fazem de si e os efeitos dessas representações na construção de suas identidades e, de maneira específica, ilustrar a concepção de feminismo que as mulheres surdas possuem. A pesquisa é de cunho qualitativo entrelaçada com a Teoria das Representações Sociais, com o foco nas representações que as Mulheres Surdas fazem de si; isto é, na maneira como elaboram e partilham simbologias significantes e construtivas de suas identidades. Por sua vez, as bases teóricas desta pesquisa provêm do campo epistêmico: feminismo, surdez e das representações sociais. As considerações finais ilustram as concepções de Mulheres Surdas sobre o feminismo e as representações sociais sobre suas identidades. Identidade pressuposta, a partir da invisibilidade, exclusão e preconceito que os outros lhes narravam, e identidade metamorfose, com empoderamento, no reconhecimento de suas diferenças e na valorização delas

Perspectivas epidemiológicas, clínicas e terapêuticas do transtorno bipolar em comorbidade com o uso de drogas: revisão de sistemática: Epidemiological, clinical and therapeutic perspectives of bipolar disorder in comorbidity with drug use: a systematic review

Conhecida como transtorno maníaco-depressivo, atualmente possui um novo nome: Transtorno Afetivo Bipolar, visto que com o passar do tempo foi se percebendo que esse transtorno não se tratava de uma alteração psicótica, e mais de um prejuízo afetivo. O transtorno bipolar possui alguns tipos, não se caracterizando em apenas uma forma, sua manifestação varia conforme o indivíduo e suas tendências, disforia e/ou euforia porém independente da forma expressa o paciente bipolar pode ter sua vida social comprometida, se não tratada, visto a irregularidade no estado de humor; bem como pode fazer uso de substâncias psicoativas, o que prejudica a sua condição clínica. Objetivo central da pesquisa é de apresentar a correlação do transtorno bipolar com o uso de drogas, mediante uma revisão de literatura integrativa realizada entre os meses de março de 2022 a julho de 2022, através da busca de artigos científicos nos bancos de dados online PubMed, Scielo e Google Acadêmico, utilizando como critério de refinamento de pesquisa artigos de todas as línguas publicados entre os anos 2000 e 2022

ATLANTIC EPIPHYTES: a data set of vascular and non-vascular epiphyte plants and lichens from the Atlantic Forest

Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts. Our work presents the first epiphyte data set with information on abundance and occurrence of epiphyte phorophyte species. All data compiled here come from three main sources provided by the authors: published sources (comprising peer-reviewed articles, books, and theses), unpublished data, and herbarium data. We compiled a data set composed of 2,095 species, from 89,270 holo/hemiepiphyte records, in the Atlantic Forest of Brazil, Argentina, Paraguay, and Uruguay, recorded from 1824 to early 2018. Most of the records were from qualitative data (occurrence only, 88%), well distributed throughout the Atlantic Forest. For quantitative records, the most common sampling method was individual trees (71%), followed by plot sampling (19%), and transect sampling (10%). Angiosperms (81%) were the most frequently registered group, and Bromeliaceae and Orchidaceae were the families with the greatest number of records (27,272 and 21,945, respectively). Ferns and Lycophytes presented fewer records than Angiosperms, and Polypodiaceae were the most recorded family, and more concentrated in the Southern and Southeastern regions. Data on non-vascular plants and lichens were scarce, with a few disjunct records concentrated in the Northeastern region of the Atlantic Forest. For all non-vascular plant records, Lejeuneaceae, a family of liverworts, was the most recorded family. We hope that our effort to organize scattered epiphyte data help advance the knowledge of epiphyte ecology, as well as our understanding of macroecological and biogeographical patterns in the Atlantic Forest. No copyright restrictions are associated with the data set. Please cite this Ecology Data Paper if the data are used in publication and teaching events. © 2019 The Authors. Ecology © 2019 The Ecological Society of Americ

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Social representations of Deaf Miriense Women about themselves: from invisibility to protagonism

Este artigo tem como objetivo analisar as representações sociais que as Mulheres Surdas fazem de si e os efeitos dessas representações na construção de suas identidades e, de maneira específica, ilustrar a concepção de feminismo que as mulheres surdas possuem. A pesquisa é de cunho qualitativo entrelaçada com a Teoria das Representações Sociais, com o foco nas representações que as Mulheres Surdas fazem de si; isto é, na maneira como elaboram e partilham simbologias significantes e construtivas de suas identidades. Por sua vez, as bases teóricas desta pesquisa provêm do campo epistêmico: feminismo, surdez e das representações sociais. As considerações finais ilustram as concepções de Mulheres Surdas sobre o feminismo e as representações sociais sobre suas identidades. Identidade pressuposta, a partir da invisibilidade, exclusão e preconceito que os outros lhes narravam, e identidade metamorfose, com empoderamento, no reconhecimento de suas diferenças e na valorização delas

CUIDADOS DE ENFERMAGEM NA LESÃO POR PRESSÃO EM PACIENTES ACAMADOS: UMA REVISÃO INTEGRATIVA

A Lesão por Pressão é uma condição na qual os tecidos moles ou proeminências ósseas podem desenvolver lesões devido à aplicação prolongada de pressão, fricção ou cisalhamento sobre a superfície da pele. A gravidade da Lesão por Pressão varia de acordo com a resistência dos tecidos afetados. Ela é classificada em quatro categorias: I – hiperemia e não branqueável; II – ruptura parcial da pele; III – perda total da espessura da pele; e IV – perda de tecido que pode expor músculos, tendões ou ossos. O presente trabalho consiste em uma revisão de literatura do tipo integrativa, no qual tem como objetivo discorrer acerca dos cuidados de enfermagem na lesão por pressão em pacientes acamados, no intuito de ampliar os conhecimentos dos estudantes, profissionais da área e cuidadores acerca do tema. Trata-se de uma revisão integrativa, na qual foi realizada uma pesquisa bibliográfica, nas bases de dados da Biblioteca Virtual da Saúde. Para garantir um cuidado eficaz, a prescrição de enfermagem deve incluir estratégias para a implementação de um plano detalhado destinado a pacientes acamados que apresentam ou têm risco de desenvolver Lesão por Pressão. É vital promover a colaboração entre a equipe multidisciplinar e a equipe de enfermagem para prevenir e reduzir as Lesões por Pressão em pacientes acamados. Um dos cuidados essenciais recomendados é a proteção das proeminências ósseas e a realização da mudança de decúbito a cada 2 horas

An update on the epigenetics of glioblastomas

Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Human Cytogenetics Laboratory. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Federal University of Pará. Institute of Biological Sciences. Molecular Biology Laboratory. Belém, PA, Brazil.Glioblastomas, also known as glioblastoma multiforme (GBM), are the most aggressive and malignant type of primary brain tumor in adults, exhibiting notable variability at the histopathological, genetic and epigenetic levels. Recently, epigenetic alterations have emerged as a common hallmark of many tumors, including GBM. Considering that a deeper understanding of the epigenetic modifications that occur in GBM may increase the knowledge regarding the tumorigenesis, progression and recurrence of this disease, in this review we discuss the recent major advances in GBM epigenetics research involving histone modification, glioblastoma stem cells, DNA methylation, noncoding RNAs expression, including their main alterations and the use of epigenetic therapy as a valid option for GBM treatment