240 research outputs found

    Current trends in the development of a green finance system: methodology and practice

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    The concept of green growth and sustainable development is turning into a global ideology guiding the transformation of national economies. The focus is shifting from quantitative assessments of performance to rational choice conditions. Rationality is becoming the decisive factor behind sustainable green growth, and a change in the financial model that supports such growth may be needed. Therefore, the most urgent problems relating to sustainable growth are the transformation of the finance system, on the one hand, and the creation of a new financial paradigm based on the principles of responsible investment and corporate social responsibility, on the other. This study aims to consider the theoretical and practical aspects of creating a national green finance model ensuring sustainable growth in the Russian Federation. The development of a green finance mechanism and a green bond market in the Baltic Sea countries is analysed to determine national features and explore the possibility of translating the Baltic experience into practices usable in Russia. The research uses economic observations, economic description, structural and logical analysis, and systems analysis. Perhaps the most significant finding is the description of a methodological framework for sustainable development theory, as seen by major schools of economic thought. Studying the experience of the Baltic Sea countries in creating a new finance model of responsible investment helped detect national features and development priorities that can be used in Russia in devising the ideology, principles, and mechanism of green growth and sustainable growth financing

    Empirical evaluation of state support measures for the agricultural industry in modern practice

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    The article presents the results of the study of the effectiveness of the state program “Development of Agriculture” in the Kaliningrad region; econometric analysis of the dependence of the results of the economic activity of agricultural enterprises on the amount of state subsidy is proposed as a research method; on the basis of the econometric models the regression-correlation analysis of the effectiveness of financial resources distribution on the main directions of the state agricultural program is conducted

    Prenosological diagnosis as an improving element of the health care of working-age population

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    Studying red blood cells in the pathogenesis of tumor growth increasingly attracts attention due to the high biological activity. There is evidence of changes in red blood cells under the influence of negative production factors. The study applied screening tests for the presence of inter-erythrocyte lagoons and luminescent red blood cells. The object of the study were military servicemen engaged in the chemical weapons storage and destruction facilities. The objective of the study was to conduct analysis of the peripheral blood with the further development of preventive measures to reduce the risk of malignancies. The results of the study revealed the following trends: a risk group for the emergence of malignant tumors includes the retired and former military servicemen. The highest percentages of positive tests for the presence of inter-erythrocyte lagoons and luminescent red blood cells were observed in the contingent group (95.1% for each indicator). Analysis of the results by age and employment structure revealed a direct correlation - the older the age and the greater the working experience is, the higher the risk of cancer development is. The risk group includes persons over 70 years old (100% of positive results for the presence of lagoons and luminescent red blood cells). High percentages of positive tests are in working intervals of 30-39 years (71.6% for lagoons and 70.1% for luminescent red blood cells), 10-19 years (58.8% for lagoons and 70.6% for luminescent red blood cells), and 20-29 years (58.6% for lagoons and 69% for luminescent red blood cells)

    Diaqua­bis­(N,N-diethyl­pyridine-3-carboxamide-κN 1)bis­{4-[2-(2,4-dioxopentan-3-yl­idene)hydrazin-1-yl]benzoato-κO}copper(II)

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    In the title compound, [Cu(C12H11N2O4)2(C10H14N2O)2(H2O)2], the CuII atom lies on a center of inversion and is coordinated by carboxyl­ate O atoms, pyridine N atoms and two water mol­ecules in an elongated octa­hedral geometry. The pyridine ring is oriented at a dihedral angle of 74.83 (12)° with respect to the benzene ring. Intra­molecular O—H⋯O and N—H⋯O hydrogen bonding is observed. The water mol­ecule is a hydrogen-bond donor to the carbonyl O atom of an adjacent carboxyl­ate group, generating a chain running along the a axis. One of the ethyl groups is disordered over two sets of sites in a 0.787 (5):0.213 ratio

    Cytogenetic aspects of occupational carcinogenic hazard

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    © 2016,International Journal of Pharmacy and Technology. All rights reserved.The effect of chemical factors of the production environment is studied with a wide range of test systems,among which the short-term tests with high sensitivity are in the foreground. We conducted a study to assess the cytogenetic status of servicemen. Micronucleus test was a convenient method of substance screening that can quickly determine the presence or absence of various compounds of cytogenetic nature. We have identified a relationship between exposure of occupational hazards and the level of micronuclei in human peripheral blood. Excess in number of micronuclei occurs at almost three times the rate in the retired servicemen. Indicator in this contingent group was 92.7%. Subject to the age,the risk group of the high chance of malignancy development is the people over age 70. 3N micronuclei level in this age group was found in 96.3%. 3N micronuclei level is found in 71.4% of representatives of the employment group of 3-9 years,while in the employment group of 30-39 years - only in 68.7%. Subject to the military force,the risk group of the high chance of malignancy development are missile,ground,and motorized rifle troops

    Pulmonary embolism and atrial fibrillation: analysis of data from the SIRENA Russian registry

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    Aim. To present the clinical characteristics and in-hospital prognosis in patients with pulmonary embolism (PE) and atrial fibrillation (AF).Material and methods. On the initiative of a working group of physicians, the basic principles of an observational prospective study (SIRENA registry) have been developed.Results. Among the 660 patients included in the registry, AF was diagnosed in almost every fourth patient — in 22,9% of cases (n=151), which reflects its high incidence in relation to PE. The prevalence of AF corresponded to such conditions as heart failure (HF) (23,2%; n=153), diabetes (15,6%; n=103), and hypertension (HTN) (65,7% n=400). The diagnosis of AF in most patients is based on the history data (n=144; 95,4%), while the first registered AF episode was verified in 7 patients (4,6%). Patients with AF were characterized by older age, significantly higher prevalence of HF (51,2%), HTN (80,8%), chronic kidney disease (18,5%), stroke or transient ischemic attack (23,2%). It is important to note the low prevalence of anticoagulant therapy (15,3%) in the group of patients with previously diagnosed AF (n=144). The prevalence of thrombolytic therapy in patients with AF was significantly lower than among patients without AF (13,9 vs 25,8% (p=0,026)), which is due to contraindications and underdiagnosis of PE. Given the predominantly senile age, high comorbidity rate in patients with AF, as well as the absence of outpatient anticoagulant therapy, in-hospital mortality in patients with PE and AF was 31,1%, and significantly differed from that in those without AF 12,6% (p=0,001). In the general group, post-mortem diagnosis of PE was noted in 7,7% of cases (n=51), of which the proportion of patients with AF was 54,9% (n=28). A possible explanation for the underestimation of PE in AF patients was an erroneous explanation of its manifestations (tachypnea, tachycardia, lower limb edema) due to concomitant HF.Conclusion. Suspicion for PE in elderly patients with AF and manifestations of HF decompensation, as well as the timely administration of anticoagulant therapy, will prevent both arterial and venous embolism

    Indicators of hormonal status of the military servicemen in the modern type of military technogenesis

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    © 2016, International Journal of Pharmacy and Technology. All rights reserved.The paper presents the results of the evaluation of the testosterone level in the military servicemen. The work at the military enterprises is characterized by storage and disposal of chemical weapons and the presence of a number of harmful factors. The effect of carcinogens and reproductive hazards in the operation environment on the hormonal system changes the levels of hormones responsible for the reproductive function of the body. It is known that the reduction in the concentration of testosterone leads to male infertility, and its increase with age can trigger the development of prostate cancer. Testosterone indicators in our study were distributed subject to the contingent, age, length of service and a type of troops. Determination of hormone was conducted by enzyme-linked immunosorbent assay (ELISA) of blood. The study revealed hormonal disorders in all contingents examined. A high-risk group involves retired and former military servicemen (high levels of testosterone were found in 52.1% of the surveyed of this contingent), persons over 70 years old (high levels of testosterone were found in 61.5% of the surveyed in this age group), the workers with length of service of 30-39 years (high levels of testosterone were found in 55.2% of the surveyed with this length of service). Low levels of testosterone were found in private soldiers (3.6% of the surveyed of this contingent), in persons aged 18-29 years (3.3% of the surveyed in this age group), and in those with length of service of 1-2 years (3.6% of the surveyed with this length of service)

    The impact of micronutrients on athletes’ vision: a retrospective analysis of revalent articles

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    The eyes, like other human organs, are deficient in nutrients during over-training, which can affect visual acuity and, accordingly, the quality of training.This article defines the importance of the organ of vision for sports results. It also provides an overview of the latest scientific research on the impact of biologically significant micronutrients on the functions of the visual analyzer with examples of products that help improve visual functions

    STUDY OF EXPRESSION OF HBD-1 AND HBD-2 GENES IN EPITHELIAL CELLS OF MUCOUS UPPER AIRWAY IN NEWBORNS WITH PNEUMONIA DEPENDING ON THE CAUSATIVE AGENT

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    Β-defensins play an important role in protecting the fetus from infection, so the expression of these antimicrobial peptides in the respiratory tract in newborns is really important. In this regard, we set a task of studying the expression of the HBD-1 and HBD-2 genes in the epithelial cells of the mucous of the upper airway in newborns with pneumonia and in healthy newborns, depending on the causative agent. Also, the polymorphic marker G(-20) A in the DEFB1 gene was associated with infectious pathology of newborns (in particular pneumonia). Methods: The microflora and the factors of congenital immunity on the mucous membranes of the upper airway have been studied in two groups: newborns with ventilator-associated and congenital pneumonia. The biological material was scrapings of epithelial cells of the mucous membrane of the upper airway of newborns and puerperas and blood. Results: It was found that the expression of the HBD-2 gene increases 2.3-fold in children who have an infectious agent, but there are no clinical manifestations of pneumonia. A significant decrease in HBD-2 (3.2 times) in patients with pneumonia caused by K. pneumonia was shown. The frequencies of alleles of the DEFB1 gene in the fetal infection group and in the comparison group: allele G - 0.66, 0.79, allele A - 0.34, 0.21, respectively. The frequencies of the genotypes of the test marker in mothers in the ventilator-associated, congenital pneumonia and the comparison group were as follows: GG - 0.78, 0.58, 0.58; AA is 0, 0.25, 0; AG - 0.22, 0.17, 0.42, respectively. In newborns allele G dominated among alleles (frequency was higher than 0.73 in all groups) and genotype GG (frequency exceeded 0.52). Conclusion: In the course of the study, it was confirmed that β-defensins protect the mucous from infectious agents. The results indicate that the genetic marker G (-20) A of the DEFB1 gene is associated with the risk of developing the child's UTI
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