Relationships Among Some Biochemical Parameters, Trace Elements and Lipid Peroxidation Levels in Women With Gestational Diabetes Mellitus

Aim:The aim of the present study was to determine levels of copper (Cu), zinc (Zn), iron (Fe), malondialdehyde and some biochemical parameters in women with gestational diabetes mellitus (GDM) compared with healthy pregnant women, and to evaluate the relationships among these parameters.Materials and Methods:The patients consisted of 56 pregnant with GDM. The control group consisted of 60 healthy pregnant women. Plasma malondialdehyde, blood glucose, insulin, glycosylated hemoglobin (HbA1c), total cholesterol, triacylglycerol and LDL-cholesterol were measured by biochemical methods. The concentrations of serum Fe, Cu and Zn were determined by flame atomic absorption spectrophotometer.Results:The levels of blood glucose, insulin, HOMA-IR, glycosylated hemoglobin (HbA1c), total cholesterol, triacylglycerol and LDL-cholesterol, levels of plasma malondialdehyde, levels of serum Fe and Cu in women with GDM group were found higher than those in healthy pregnant women. However, levels of serum Zn were significantly lower in GDM pregnants than those in the healthy pregnant women. There were significant negative correlations between LDL-cholesterol and Cu levels of GDM subjects. Additionally, there were significant negative correlation between LDL-cholesterol and plasma malondialdehyde levels. However, there were significant positive correlations between serum Fe and plasma malondialdehyde levels.Conclusion:Our findings emphasize the significant deficiencies of Zn levels and the significant elevation of malondialdehyde, hyperglycemia and hyperlipidemia in women with GDM. Therefore, supplementation with Zn element involved in the antioxidative system may increase antioxidative enzyme activities, and consequently, an improvement in fetal and maternal complications may be expected

Effect of different salt concentrations on the resistance of maize cultivars 1. Some morphological and yield characteristics in early growth

ABSTRACT Nine different maize cultivars Lr Armigo, Pollen, C-955, Frassino, Güneş-626, Goldeliza, Apache, LG-55 and Flash were grown in water culture (Hydroponics) salinized with 25, 50, 75 and 100 mMol NaCl and tested for salt tolerance during germination, emergence and early growing stage. Germination rate, coleoptile length and root lenght and plant height, number of leaves and stem diameter in addition to the leaf, stem and root dry matter yields were the investigated characteristics. There were significant variations among the cultivars in terms of salt resistance (or tolerance). Flash and Güneş-626 were the most resistant cultivars surviving even under 100 mMol salt concentrations. 25 mMol salt concentration was not harmful for any genotype, whereas 100 mMol salinity was highly detrimental, also lethal for some cultivars (Apache, LG-55). However, it should be pointed out that some cultivars such as Lr Armigo, Pollen, Flash and Güneş-626 had satisfactory growth rthym in above mentioned high salt concentrations.ABSTRACT Nine different maize cultivars Lr Armigo, Pollen, C-955, Frassino, Güneş-626, Goldeliza, Apache, LG-55 and Flash were grown in water culture (Hydroponics) salinized with 25, 50, 75 and 100 mMol NaCl and tested for salt tolerance during germination, emergence and early growing stage. Germination rate, coleoptile length and root lenght and plant height, number of leaves and stem diameter in addition to the leaf, stem and root dry matter yields were the investigated characteristics. There were significant variations among the cultivars in terms of salt resistance (or tolerance). Flash and Güneş-626 were the most resistant cultivars surviving even under 100 mMol salt concentrations. 25 mMol salt concentration was not harmful for any genotype, whereas 100 mMol salinity was highly detrimental, also lethal for some cultivars (Apache, LG-55). However, it should be pointed out that some cultivars such as Lr Armigo, Pollen, Flash and Güneş-626 had satisfactory growth rthym in above mentioned high salt concentrations

Ozmatik basıncının bazı kültür bitkilerinin erken gelişme dönemindeki etkileri I.Çimlenme ve büyüme özellikleri

In this study conducted under the (Hidroponic) RAF system conditions in physiology laboratory of Field Crops Department of Agriculture Faculty Ege University, effect of different osmotic pressures (0, 2,4, 6, 8, 10 m Bar NaCl) in growth medium on the speed and total rate of germination, lenght of root and seedling characteristics of different crop cultivars such as maise (Zea mays), alfalfa (Medicago sativa) and intermediate wheatgrass (Agropyron intermedium) at early growing stage. Results indicated that alfalfa reached the highest values and maise cultivars followed it and intermediate wheatgrass at this stage could not survive in osmotic pressures (NaCl concentrations) exceeding 4 mBar. Maize cultivars reached the highest values in terms of lenght of root and seedling, on the other hand there was not any growth record of intermediate wheatgrass with regard to any characteristic in osmotic pressures exceeding 4 mBar.Ege Üniversitesi Ziraat Fakültesi Tarla Bitkileri Bölümü Fizyoloji Laboratuvan Hidroponic RAF Sistemi koşullarında yürütülen bu çalışmada, büyüme ortamındaki 0,2,4, 6,8 ve l0 mBar'lık ozmotik basınçların mısır (Zea mays)., Yonca (Medicago sativa) ve Mavi ayrık (Agropyron intermedium) gibi bitkilere ait çeşitlerin erken gelişme döneminde çimlenme hızı ve gücü, kök uzunluğu ve fide boylarına etkisi incelenmiştir. Sonuçlar, çimlenme hızı ve gücü açısından yoncanın en yüksek değerlere ulaştığım, bunu mısır çeşitlerinin izlediği ve mavi ayrığın en düşük değerlere sahip olduğunu göstermiştir. Kök uzunluğu ve fide boyu bakımından ise mısır çeşitlerinin en yüksek değerlere sahip olduğu saptanmış, buna karşılık mavi ayrığın 6 mBar'dan sonraki tuz (NaCl) yoğunluğunda bu karakterler açısından herhangi bir gelişme kaydedilmemiştir

The relationship between subclinic atherosclerosis and red cell distribution width in patients with metabolic syndrome

Objectıve: We have investigated the possible associationbetween red cell distribution width (RDW) and subclinicatherosclerosis which can assessed by carotidintima-media thickness (CIMT) measurement in patientswith metabolic syndrome (MetS).Methods: 74 patients with MetS were enrolled to thestudy. Patients were divided into 2 groups according tocarotid intima-media thickness (CIMT) measurement: 35patients with CIMT≥1.0 mm were at group 1 and 39 patientswith CIMT<1.0 mm were at group 2. RDW weremeasured using an automated blood cell counter.Results: The RDW level was not statistically significantin patients with CIMT≥1,0 mm than in patients withCIMT<1,0 mm (13.73±0.79% vs. 13.77±1.04 %; p=0.85).Conclusion: In our study, we found that RDW was notdifferent in the MetS patients with CIMT≥1.0 mm comparedwith the MetS patients with CIMT<1.0 mm.Key words: red cell distribution width, metabolic syndrome,complete blood coun

Relation of left atrial volume index with subclinical atherosclerosis at patients with metabolic syndrome

Metabolik sendrom (MetS) ateroskleroza, sol ventrikül yapı ve fonksiyonlarında bozulmaya neden olur. Diyastolik disfonksiyon (DD) subklinik kardiyak hasarın erken dönem bulgusudur. Sol atriyal volüm DD’un ciddiyetini ve süresini göstermede bir belirteç olarak kullanılabilir. Çalışmamızda, MetS’lu hastalarda sol ventrikül DD ve derecesini, sol atriyal volüm indeksi (SAVİ) ile birlikte değerlendirdik ve bunun karotis intima media kalınlığı (KİMK) ile tespit edilen subklinik aterosklerozla ilişkisini araştırdık. Çalışmaya MetS’lu 82 hasta alındı. Hastalar KİMK ölçümüne göre, KİMK?1,0 mm olan 35 hasta grup 1, KİMK<1,0 mm olan 47 hasta ise grup 2 olarak ikiye ayrıldı. Gruplarda sol ventrikül sistolik ve diyastolik fonksiyonları değerlendirildi, SAVİ hesaplandı. Grup 1’de DD görülme oranı istatistiksel olarak anlamlı yüksek tespit edildi (p:0,001). Evre 1 DD ve evre 2 DD açısından gruplar arasında istatistiksel olarak anlamlı fark tespit edilmedi (p:0,079). SAVİ değerleri grup 1 ve grup 2’de sırasıyla 32,6±6,0 ml/m2 ve 26,6±4,7 ml/m2 olarak hesaplandı. İki grup arasında istatistiksel olarak anlamlı fark tespit edildi (p: 0,001). SAVİ ile korelasyon bakıldığında; KİMK ile pozitif korelasyon izlendi. Konvansiyonel ve doku Doppler görüntülemede elde edilen verilerle SAVİ arasında korelasyon bakıldığında; sol ventrikül kitle indeksi, septal ve lateral E/Em oranları arasında pozitif korelasyon, septal ve lateral Em/Am oranları ile negatif korelasyon izlendi. Çalışmamızda subklinik aterosklerozun noninvazif göstergesi olan KİMK’nın yüksek olduğu grupta SAVİ değerleri yüksek bulunmuştur. Buna ek olarak çalışmaya alınan tüm hastalar değerlendirildiğinde, diyastolik disfonksiyonun varlığı ve şiddetiyle ilişkili olarak SAVİ değerlerinin arttığı gözlenmiştir.Metabolic syndrome (MetS) increases the frequency of cardivovascular events by causing atherosclerosis and impairment at left ventricle structure and function. Diastolic dysfunction (DD) is an early finding of subclinical cardiac injury. Left atrial volume may be used as an indicator for demonstrating severity and duration of DD. With this study, we investigated the relationship between subclinical atherosclerosis ,evaluated by carotid intima-media thickness (CIMT) measurement and subclinical cardiac injury evaluated by diastolic functions and left atrial volume index (LAVI) in MetS patients. 82 patients with MetS were enrolled to the study. Patients were divided into 2 groups according to CIMT measurement: 35 patients with CIMT&#8805;1.0 mm were at group 1 and 47 patients with CIMT<1.0 mm were at group 2. Systolic and diastolic functions were evaluated, LAVI was calculated. Frequency of DD was found statistically significantly higher in group 1 (p=001). There was no difference between groups for grade I DD and grade (p=0079). LAVI values were calculated as 32.6±6.0 ml/m2 and 26.6±4.7 ml/m2 at group 1 and 2,respectively.There was a statistically significant difference between two groups.When correlation with LAVI was investigated,a positive correlation with CIMT was observed. When correlation between data from conventional and tissue Doppler imaging and LAVI was evaluated,there were positive correlations for left ventricle mass index, septal and lateral E/Em rates, and negative correlations for septal and lateral Em/Am rates. LAVI was found to be high in-patient with higher CIMT value which is non-invasive indicator of subclinical atherosclerosis. In addition, in all patients, a relation was observed between presence and severity of diastolic dysfunction and increase in LAVI value

Right heart thrombus entrapped in patent foramen ovale with pulmonary embolism in a patient with primary hypercoagulable state

Thromboembolic disease is a potentially severe pathology.When its clinical feature implies a massive occlusionof the arterial pulmonary tree and a cardiac failure is ensued,it can be seriously life threatening even for youngpatients. Less frequent features as right or left atriumthrombosis could increase morbidity and mortality of thisdisease.We report a case of massive right pulmonary embolism(PE) with entrapped thrombus in patent foramen ovaleand right heart failure in a 32- year-old man. Transthoracicechocardiography showed a right atrial thrombusattached to the inter-atrial septum. Following the diagnosisof right heart thrombosis with massive PE, infusion oftissue type plasminogen activator (100 mg in two hours)was administered. Echocardiography performed two daysafter thrombolysis showed a significant decrease in theright ventricular size and complete lysis of the thrombusin the right heart. By genetic examination, he proved tohave factor V ’Leiden’ gene and two thrombophilia genes,all of which were positive in the heterozygous state. Hehad also a high serum homocysteine.Key words: pulmonary embolism, hypercoagulable state,thrombolytic therapy, patent foramen oval