2,780 research outputs found

    The Grizzly, September 8, 2005

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    Hurricane Katrina Devastates Louisiana • Constitution Stirs up Debate in Iraq • Music and Comedy Greet Class of 2009 • Acting Out Project • An Ursinus Freshman Excels at an Unlikely Sport • What\u27s New at the Berman? Preview of Ursinus\u27 Museum of Art • Stopping the Stork • Food Pyramid Overview • Opinions: Holloway Case Should Raise Awareness; Positives and Negatives of Freshman Orientation; My House Party Dreams; Changes Around Campus • Second Half Comeback Propels Crusaders Past Bears • Field Hockey Drops Season Openerhttps://digitalcommons.ursinus.edu/grizzlynews/1587/thumbnail.jp

    The Grizzly, September 15, 2005

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    Gas Prices Continue to Rise • Campus and Local Community Begin Relief Efforts • Students Share Study Abroad Experiences • The Deal with the Meal Deal • One of Ursinus\u27 Own Performs Professionally • Watch Out, Employers: You Could be Next! • How Much is Too Much? Your Guide to Avoiding Portion Distortion • Excitement Building in Kaleidoscope • Beyond the Condom: Guide to Safe Sex • Opinions: New Price of Driving; Ursinus, U are Worth it • Irony of Work Study • Things They Didn\u27t Teach You at Freshman Orientation • Who Says Division III Players Can\u27t Go Pro?https://digitalcommons.ursinus.edu/grizzlynews/1692/thumbnail.jp

    Heavy hadron spectroscopy and the bag model

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    Some time ago a slightly improved variant of bag model (the modified bag model) suitable for the unified description of light and heavy hadrons was developed. The main goal of the present work was to calculate the masses of the ground state baryons containing bottom quarks in the framework of this model. For completeness the predictions for other heavy hadrons are also given. The reasonable agreement of our results with other theoretical calculations and available experimental data suggests that our predictions could serve as a useful complementary tool for the interpretation of heavy hadron spectra.Comment: 18 pages, 9 tables, references to experiments updated, rms deviations given in some table

    The Grizzly, September 29, 2005

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    Fire Safety on Campus • UC Tuition Series Part I: An Overview • Study Abroad in Madrid Returns • Campus Drive Removal • Upcoming RHA Events • Backed Up Your Computer Lately? • Club Spotlight: Le Cercle Francais • Seven Day Itch • The Drift Away Cafe • Main Street Walks for STD Awareness • Sigma Gamma Rho Walks for Sickle Cell Anemia • Update from Mexico • Heefner Organ Recital Series at Ursinus College • Readjusting: Tulane Students at Ursinus • Oktoberfest: An Ursinus Tradition • How do You Take Your Caffeine? • Opinions: Activities Fair Helps Students Get Involved; Face Off; Gangsta Mentality; This Year\u27s Fringe Festival Lived Up to its Name • Just for Kicks, Lady Bears Win Six • Bears Strand Shorewomen • Breaking the Moldhttps://digitalcommons.ursinus.edu/grizzlynews/1694/thumbnail.jp

    Surface sensing for biofilm formation in Pseudomonas aeruginosa

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    YesAggregating and forming biofilms on biotic or abiotic surfaces are ubiquitous bacterial behaviors under various conditions. In clinical settings, persistent presence of biofilms increases the risks of healthcare-associated infections and imposes huge healthcare and economic burdens. Bacteria within biofilms are protected from external damage and attacks from the host immune system and can exchange genomic information including antibiotic-resistance genes. Dispersed bacterial cells from attached biofilms on medical devices or host tissues may also serve as the origin of further infections. Understanding how bacteria develop biofilms is pertinent to tackle biofilm-associated infections and transmission. Biofilms have been suggested as a continuum of growth modes for adapting to different environments, initiating from bacterial cells sensing their attachment to a surface and then switching cellular physiological status for mature biofilm development. It is crucial to understand bacterial gene regulatory networks and decision-making processes for biofilm formation upon initial surface attachment. Pseudomonas aeruginosa is one of the model microorganisms for studying bacterial population behaviors. Several hypotheses and studies have suggested that extracellular macromolecules and appendages play important roles in bacterial responses to the surface attachment. Here, I review recent studies on potential molecular mechanisms and signal transduction pathways for P. aeruginosa surface sensing.This work is supported by University of Bradfor

    Solulin reduces infarct volume and regulates gene-expression in transient middle cerebral artery occlusion in rats

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    <p>Abstract</p> <p>Background</p> <p>Thrombolysis after acute ischemic stroke has only proven to be beneficial in a subset of patients. The soluble recombinant analogue of human thrombomodulin, Solulin, was studied in an <it>in vivo </it>rat model of acute ischemic stroke.</p> <p>Methods</p> <p>Male SD rats were subjected to 2 hrs of transient middle cerebral artery occlusion (tMCAO). Rats treated with Solulin intravenously shortly before reperfusion were compared to rats receiving normal saline i.v. with respect to infarct volumes, neurological deficits and mortality. Gene expression of IL-6, IL-1β, TNF-α, MMP-9, CD11B and GFAP were semiquantitatively analyzed by rtPCR of the penumbra.</p> <p>Results</p> <p>24 hrs after reperfusion, rats were neurologically tested, euthanized and infarct volumes determined. Solulin significantly reduced mean total (p = 0.001), cortical (p = 0.002), and basal ganglia (p = 0.036) infarct volumes. Hippocampal infarct volumes (p = 0.191) were not significantly affected. Solulin significantly downregulated the expression of IL-1β (79%; p < 0.001), TNF-α (59%; p = 0.001), IL-6 (47%; p = 0.04), and CD11B (49%; p = 0.001) in the infarcted cortex compared to controls.</p> <p>Conclusions</p> <p>Solulin reduced mean total, cortical and basal ganglia infarct volumes and regulated a subset of cytokines and proteases after tMCAO suggesting the potency of this compound for therapeutic interventions.</p

    Phenomenology of Heavy Meson Chiral Lagrangians

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    The approximate symmetries of Quantum ChromoDynamics in the infinite heavy quark (Q=c,bQ=c,b) mass limit (mQm_Q \to \infty) and in the chiral limit for the light quarks (mq0,  q=u,d,sm_q \to 0,\;q=\,u,\,d,\,s) can be used together to build up an effective chiral lagrangian for heavy and light mesons describing strong interactions among effective meson fields as well as their couplings to electromagnetic and weak currents, including the relevant symmetry breaking terms. The effective theory includes heavy (QqˉQ \bar q) mesons of both negative and positive parity, light pseudoscalars, as well as light vector mesons. We summarize the estimates for the parameters entering the effective lagrangian and discuss in particular some phenomenologically important couplings, such as gBBπg_{B^* B \pi}. The hyperfine splitting of heavy mesons is discussed in detail. The effective lagrangian allows for the possibility to describe consistently weak couplings of heavy (B,DB,\, D) to light (π,ρ,K,\pi,\, \rho, \, K^*,\, etc.) mesons. The method has however its own limitations, due to the requirement that the light meson momenta should be small, and we discuss how such limitations can be circumvented through reasonable ansatz on the form factors. Flavour conserving (e. g. BBγB^* \to B\, \gamma) and flavour changing (e. g. BKγB \to K^* \, \gamma) radiative decays provide another field of applications of effective lagrangians; they are discussed together with their phenomenological implications. Finally we analyze effective lagrangians describing heavy charmonium- like (QˉQ\bar Q Q) mesons and their strong and electromagnetic interactions. The role of approximate heavy quark symmetries for this case and the phenomenological tests of these models are also discussed.Comment: 92 pages, LaTeX, 17 figures, to appear in Physics Reports, page size shortened to fit american forma

    An overview of NMR-based metabolomics to identify secondary plant compounds involved in host plant resistance

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    Secondary metabolites provide a potential source for the generation of host plant resistance and development of biopesticides. This is especially important in view of the rapid and vast spread of agricultural and horticultural pests worldwide. Multiple pests control tactics in the framework of an integrated pest management (IPM) programme are necessary. One important strategy of IPM is the use of chemical host plant resistance. Up to now the study of chemical host plant resistance has, for technical reasons, been restricted to the identification of single compounds applying specific chemical analyses adapted to the compound in question. In biological processes however, usually more than one compound is involved. Metabolomics allows the simultaneous detection of a wide range of compounds, providing an immediate image of the metabolome of a plant. One of the most universally used metabolomic approaches comprises nuclear magnetic resonance spectroscopy (NMR). It has been NMR which has been applied as a proof of principle to show that metabolomics can constitute a major advancement in the study of host plant resistance. Here we give an overview on the application of NMR to identify candidate compounds for host plant resistance. We focus on host plant resistance to western flower thrips (Frankliniella occidentalis) which has been used as a model for different plant species

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

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    This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good
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