Relational Resources for Emerging Markets\u27 Non-Technological Innovation: Insights from China and Taiwan

Carta del editor D. José Lazaro, a D. Pedro Dorado Montero, comunicándole haber pagado su cuota de la Unión Internacional de Derecho Penal

Questioning the Appropriateness of Examining Guanxi in a Wasta Environment: Why Context Should be Front and Center in Informal Network Research. A Commentary on “De-Linking From Western Epistemologies: Using Guanxi-Type Relationships to Attract and Retain Hotel Guests in the Middle East

n this commentary we reflect on Shaalan, Eid, and Tourky’s (2022)article in which they investigated the Chinese concept and practice of guanxi in the Middle East1, a region in which wasta represents the common way of informal networking. While we encourage and welcome research into informal networks, we have serious concerns about the conceptual and methodological approaches taken by Shaalan et al.(2022) in investigating informal networks in the Middle East and we explain herein why we do not believe guanxi should have been used in place of wasta. In this commentary, we commence by introducing wasta,the dominant concept in the Middle East, which Shaalan et al.(2022) disregarded. Then we reflect on the conceptual approach of researching an indigenous network construct in a foreign environment of a different culture which already has its own informal networks. In the commentary we also point out areas of concern in relation to research design and methodology. Finally, we provide suggestions for future research on informal networks, and we explicitly encourage further debate which draws on our commentary

Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment

Pancreatic cancer is one of the deadliest types of cancer, with a five-year survival rate of only 10%. Nanotechnology offers a novel perspective to treat such deadly cancers through their incorporation into radiotherapy and chemotherapy. However, the interaction of nanoparticles (NPs) with cancer cells and with other major cell types within the pancreatic tumor microenvironment (TME) is yet to be understood. Therefore, our goal is to shed light on the dynamics of NPs within a TME of pancreatic origin. In addition to cancer cells, normal fibroblasts (NFs) and cancer-associated fibroblasts (CAFs) were examined in this study due to their important yet opposite roles of suppressing tumor growth and promoting tumor growth, respectively. Gold nanoparticles were used as the model NP system due to their biocompatibility and physical and chemical proprieties, and their dynamics were studied both quantitatively and qualitatively in vitro and in vivo. The in vitro studies revealed that both cancer cells and CAFs take up 50% more NPs compared to NFs. Most importantly, they all managed to retain 70–80% of NPs over a 24-h time period. Uptake and retention of NPs within an in vivo environment was also consistent with in vitro results. This study shows the paradigm-changing potential of NPs to combat the disease.Medicine, Faculty ofScience, Irving K. Barber Faculty of (Okanagan)Non UBCComputer Science, Mathematics, Physics and Statistics, Department of (Okanagan)Pathology and Laboratory Medicine, Department ofReviewedFacultyResearche