Dark Web Analytics : A Comparative Study of Feature Selection and Prediction Algorithms

The value and size of information exchanged through dark-web pages are remarkable. Recently Many researches showed values and interests in using machine-learning methods to extract security-related useful knowledge from those dark-web pages. In this scope, our goals in this research focus on evaluating best prediction models while analyzing traffic level data coming from the dark web. Results and analysis showed that feature selection played an important role when trying to identify the best models. Sometimes the right combination of features would increase the model’s accuracy. For some feature set and classifier combinations, the Src Port and Dst Port both proved to be important features. When available, they were always selected over most other features. When absent, it resulted in many other features being selected to compensate for the information they provided. The Protocol feature was never selected as a feature, regardless of whether Src Port and Dst Port were available

Investigation of Nano-Bio Interactions within a Pancreatic Tumor Microenvironment for the Advancement of Nanomedicine in Cancer Treatment

Pancreatic cancer is one of the deadliest types of cancer, with a five-year survival rate of only 10%. Nanotechnology offers a novel perspective to treat such deadly cancers through their incorporation into radiotherapy and chemotherapy. However, the interaction of nanoparticles (NPs) with cancer cells and with other major cell types within the pancreatic tumor microenvironment (TME) is yet to be understood. Therefore, our goal is to shed light on the dynamics of NPs within a TME of pancreatic origin. In addition to cancer cells, normal fibroblasts (NFs) and cancer-associated fibroblasts (CAFs) were examined in this study due to their important yet opposite roles of suppressing tumor growth and promoting tumor growth, respectively. Gold nanoparticles were used as the model NP system due to their biocompatibility and physical and chemical proprieties, and their dynamics were studied both quantitatively and qualitatively in vitro and in vivo. The in vitro studies revealed that both cancer cells and CAFs take up 50% more NPs compared to NFs. Most importantly, they all managed to retain 70–80% of NPs over a 24-h time period. Uptake and retention of NPs within an in vivo environment was also consistent with in vitro results. This study shows the paradigm-changing potential of NPs to combat the disease.Medicine, Faculty ofScience, Irving K. Barber Faculty of (Okanagan)Non UBCComputer Science, Mathematics, Physics and Statistics, Department of (Okanagan)Pathology and Laboratory Medicine, Department ofReviewedFacultyResearche