Avances en tecnología farmacéutica

Avances en tecnología farmacéutica

Influence of the number of daily pills and doses on adherence to antiretroviral treatment: a 7-year study

[EN] What is known and objective: Antiretroviral treatment (ART) is hampered by complicated regimens, high pill burden, drug–drug interactions, and frequent short- and long-term adverse effects, leading to decreased adherence. Over recent years, considerable effort has been directed at developing regimens that are less burdening. We undertook a 7-year retrospective study of the records of 264 HIV-infected subjects enrolled in a pharmaceutical care programme to document the progress made and to study the influence of the number of ART pills and doses on the level of treatment adherence. Methods: Antiretroviral dispensing records were analysed for the number of pills and doses administered and the ART adherence rate estimated. Results and discussion: In 2005, the patients took a mean of 6 2 pills daily (CI 95%: 5 9–6 6), and 92 9% of them were on a twice-a-day (BID) dosage regimen. By 2012, the mean number of pills was reduced to 4 1 (CI 95%: 3 8–4 4), and only 50 9% were on a BID regimen. No statistically significant relation was observed between number of daily pills and doses and ART adherence reached by the patients in any of the analyses performed. What is new and conclusions: There has been a continuous reduction in the number of pills and doses of antiretrovirals taken by individual patients over the last 7 years due largely to the introduction of improved treatments and regimens. More daily pills or doses was not associated with worse ART adherence in our pharmaceutical care programme

Implementación de actividades de edición y construcción de contenidos de Wikipedia en diversas asignaturas del Grado en Farmacia

Memoria ID-0289. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015

Medicamentos en la senectud

Medicamentos en la senectud

Pulmonary versus Systemic Delivery of Antibiotics: Comparison of Vancomycin Dispositions in the Isolated Rat Lung▿

Vancomycin dispositions in the respiratory system were compared after systemic and inhalatory administration under two respiratory conditions using the isolated-lung model. Inhalatory delivery led to much higher drug levels in pulmonary tissue and fluids. The respiratory pattern affects vancomycin disposition in the pulmonary system regardless of the administration route

Wikipedia como herramienta de aprendizaje en el área de Farmacia y Tecnología Farmacéutica

Memoria ID-241. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2013-2014