The rotation vs translation behavior during habitual opening and closing movements of the mandible and the relationship to movement paths of condylar points - evaluations of the associated project of the SHIP study

When recording condylar movement paths with the aid of electronic measuring systems, it is often found that, especially in jaw opening and closing movements, excursive and incursive paths of movement are not congruent but run separately, independently of one another to a greater or lesser degree. The objective of the study was to investigate this phenomenon in the context of rotation vs translation behavior, also taking into consideration additional side-specific condylar movement patterns. For this purpose, the electronic movement records of habitual jaw opening of 259 participants of the associated project of the population-representative basic study SHIP 0 were evaluated. The condylar movement path (condylar tracing, ConTrac) at the arbitrary axis point, the excursion vs incursion behavior in the condylar tracing grid (ExlnGrid), and the rotation vs translation behavior (RotTrans) were classified, and the translational condylar path and the maximum angle of rotation were determined metrically. Relationships between the parameters ConTrac, ExlnGrid, and RotTrans were statistically analyzed using cross tabulations and Spearman's correlation coefficient. Only about 18% of ConTrac showed congruence of excursive and incursive movement path components, while 39% demonstrated noncongruent paths, and 43% showed further conspicuous features in the movement path. For the parameter ExlnGrid, recognizable to highly pronounced loop formation patterns to a degree of 89% were observed in the condylar tracing grid. An average of 12.5 mm (min 2.1 mm, max 21.7 mm) was determined for the purely translational component of the condylar movement path, and 32.1 degrees (min 12 degrees, max 45 degrees) for the maximum angle of rotation. Concerning the rotation vs translation behavior, the linear basic pattern occurred at around 9%; the sigmoidal pattern at 28%; and the hysteretic, loopy or irregular pattern at 63%. The parameters RotTrans and ExlnGrid showed a strong correlation, whereas the strength of the correlation for ConTrac and ExlnGrid or RotTrans and ConTrac was evaluated as weak or very weak. The rotation vs translation behavior influences condylar movement paths in the positional relationship of excursive and incursive components. The visualization of several condylar movement paths in the form of a condylar tracing grid helps to capture complex rotational and translational motion components of the real condyles more effectively than the assessment of a single condylar movement path

Standard and limit values for the symmetry of articulation parameters in the temporomandibular joint area - evaluations of the associated project of the SHIP study

The articulation parameters, especially the horizontal condylar inclination angle (HCI), the Bennett angle (BA), and the immediate side shift (ISS) were determined in 259 subjects (100 males; 159 females) of the associated project with reference to the population-representative baseline study (Study of Health in Pomerania, SHIP 0). The evaluations were based on a clinical functional status and electronic motion recording with the ultrasonic measuring system Jaw Motion Analyser (JMA, Zebris, Isny, Germany). The reference plane, to which all measured values were represented and the HCI calculated, was the hinge axis infraorbital plane (HA-IOP). The HCI was determined after an excursive movement with a length of 4 mm to the HA-IOP in the sagittal view and the BA after a mediotrusive excursion movement of 6 mm in the horizontal view to the midsagittal plane. For the standard and limit values, the average value in addition to the standard deviation and the 10th and 90th percentile value (10th percentile value, 90th percentile value) were determined: HCI right 52.1 +/- 10.14 degrees (39.4 degrees, 64.0 degrees), HCI left 53.1 +/- 9.67 degrees (42.3 degrees, 67.0 degrees), BA right 15.2 +/- 7.53 degrees (6.7 degrees, 25.0 degrees), BA left 14.2 +/- 7.84 degrees (5.4 degrees, 24.1 degrees). The HCI was approximately 2 to 3 degrees larger in females (males: right 50.5 +/- 9.47 degrees, left 51.9 +/- 8.99 degrees; females: right 53.1 +/- 10.42 degrees, left 53.8 +/- 10.03 degrees). Likewise, the BA in the age group >= 40 years (males: right 14.4 +/- 6.62 degrees, left 13.1 +/- 7.14 degrees; females: right 17.0 +/- 9.02 degrees, left 16.9 +/- 8.72 degrees). The latter proved to be statistically significant in the t test for independent samples, assuming variance equivalence on the right, with P =0.009, and with rejection of the variant equivalence on the left, with P = 0.002. The right and left HCI and BA joint values showed highly significant linear dependence at P = 40 years with assumed variance equality than in the age group < 40 years (P = 0.002 right, P = 0.003 left). The groups relating to the Helkimo index (HI) did not differ significantly in all function-specific parameters. If it is assumed that there is no significant influence on the occlusion if the HCI values differ by 7 to 8 degrees from the average value, only approximately one third of all cases (35.1%) were characterized by a purely average value setting in the articulator. In 41.7% of cases, one joint value was situated outside the average value range; in 23.2% of the cases both values were outside the average value range. Without a measurement of the condylar path inclination, however, it is impossible to decide to what extent the HCI deviates from the average value, and which joint side is larger or smaller than the other and to what extent. These results suggest that in extensive and complex cases, the articulator should be adjusted according to individual, function-specific joint values

Transcutaneous auricular vagus nerve stimulation for the treatment of myoarthropatic symptoms in patients with craniomandibular dysfunction – a protocol for a randomized and controlled pilot trial

Abstract Background Temporomandibular disorders (TMD) are a collective term for pain and dysfunction of the masticatory muscles and the temporomandibular joints. The most common types of TMD are pain-related, which may impact the psychological behavior and quality of life. Currently, the most popular methods for the treatment of TMD patients are occlusal splint therapy, often in combination with physical- and/or pharmacotherapy. However, due to the complexity of etiology, the treatment of chronic TMD remains a challenge. Recently, CE-certified systems for non-invasive VNS (transcutaneous auricular vagus nerve stimulation, taVNS) have become available and show positive effects in the treatment of chronic pain conditions, like migraine or fibromyalgia, with which TMD shares similarities. Therefore, it is the main purpose of the study to evaluate the feasibility of daily taVNS against chronic TMD and to assess whether there is an improvement in pain severity, quality of life, and kinetic parameters. Methods This study is designed as a single-blinded, double-arm randomized controlled trial (RCT) in a 1:1 allocation ratio. Twenty adult patients with chronical TMD symptoms will be enrolled and randomized to stimulation or sham group. In the stimulation group, taVNS is performed on the left tragus (25 Hz, pulse width 250 µs, 28 s on/32 s off, 4 h/day). The sham group will receive no stimulation via a non-functional identical-looking electrode. Validated questionnaire data and clinical parameters will be collected at the beginning of the study and after 4 and 8 weeks. The compliance of a daily taVNS of patients with chronical TMD will be evaluated via a smartphone app recording daily stimulation time and average intensity. Additionally, the treatment impact on pain severity and quality of life will be assessed with different questionnaires, and the effect on the mandibular mobility and muscle activity will be analyzed. Discussion This is the first clinical trial to assess the feasibility of taVNS in patients with chronic TMD symptoms. If taVNS improves the symptoms of TMD, it will be a significant gain in quality of life for these chronic pain patients. The results of this pilot study will help to determine the feasibility of a large-scale RCT. Trial registration This study has been registered in the DRKS database (DRKS00029724)